Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT1G31230 - ( AK-HSDH I (ASPARTATE KINASE-HOMOSERINE DEHYDROGENASE I) aspartate kinase/ homoserine dehydrogenase )

12 Proteins interacs with AT1G31230
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G14810

Predicted

Synthetic Rescue

Gene neighbors method

Co-expression

FSW = 0.1324

Class C:

plastid

SEMIALDEHYDE DEHYDROGENASE FAMILY PROTEIN
AT4G19710

Predicted

Enriched domain pair

Phylogenetic profile method

Co-expression

FSW = 0.1778

Class C:

plastid

BIFUNCTIONAL ASPARTATE KINASE/HOMOSERINE DEHYDROGENASE PUTATIVE / AK-HSDH PUTATIVE
AT5G56030

Predicted

Affinity Capture-MS

FSW = 0.0448

Unknown

HSP81-2 (HEAT SHOCK PROTEIN 81-2) ATP BINDING
AT5G52640

Predicted

synthetic growth defect

Affinity Capture-MS

FSW = 0.0077

Unknown

ATHSP901 (HEAT SHOCK PROTEIN 901) ATP BINDING / UNFOLDED PROTEIN BINDING
AT1G20140

Predicted

synthetic growth defect

FSW = 0.0346

Unknown

ASK4 (ARABIDOPSIS SKP1-LIKE 4) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT2G30050

Predicted

Synthetic Lethality

FSW = 0.0662

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT1G80410

Predicted

synthetic growth defect

FSW = 0.0137

Unknown

EMB2753 (EMBRYO DEFECTIVE 2753) BINDING
AT3G01340

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0682

Unknown

PROTEIN TRANSPORT PROTEIN SEC13 FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G25230

Predicted

Synthetic Lethality

FSW = 0.1048

Unknown

ROF1 (ROTAMASE FKBP 1) FK506 BINDING / CALMODULIN BINDING / PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
AT5G13780

Predicted

synthetic growth defect

FSW = 0.0126

Unknown

GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE
AT5G42190

Predicted

synthetic growth defect

FSW = 0.0299

Unknown

ASK2 (ARABIDOPSIS SKP1-LIKE 2) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT3G02020

Predicted

Synthetic Rescue

FSW = 0.1381

Unknown

AK3 (ASPARTATE KINASE 3) ASPARTATE KINASE

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454