Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT2G19770 - ( PRF5 (PROFILIN5) actin binding / actin monomer binding )

24 Proteins interacs with AT2G19770
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G12360

Predicted

Synthetic Lethality

FSW = 0.0641

Unknown

KEU (KEULE) PROTEIN TRANSPORTER
AT4G04910

Predicted

Synthetic Lethality

FSW = 0.0287

Unknown

NSF (N-ETHYLMALEIMIDE SENSITIVE FACTOR) ATP BINDING / BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT4G29350

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.2207

Unknown

PFN2 (PROFILIN 2) ACTIN BINDING / PROTEIN BINDING
AT3G12110

Predicted

interaction prediction

two hybrid

two hybrid

two hybrid

Phenotypic Suppression

Synthetic Lethality

Phenotypic Enhancement

Affinity Capture-Western

Reconstituted Complex

Synthetic Rescue

biochemical

interologs mapping

Enriched domain pair

Co-expression

FSW = 0.0247

Unknown

ACT11 (ACTIN-11) STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT1G11680

Predicted

Synthetic Lethality

FSW = 0.0266

Unknown

CYP51G1 (CYTOCHROME P450 51G1) OXYGEN BINDING / STEROL 14-DEMETHYLASE
AT5G45970

Predicted

Phenotypic Suppression

FSW = 0.0315

Unknown

ARAC2 (ARABIDOPSIS RAC-LIKE 2) GTP BINDING
AT2G19760

Predicted

Gene neighbors method

Phylogenetic profile method

Co-expression

FSW = 0.3841

Unknown

PRF1 (PROFILIN 1) ACTIN BINDING
AT3G09900

Predicted

interaction prediction

FSW = 0.0581

Unknown

ATRABE1E (ARABIDOPSIS RAB GTPASE HOMOLOG E1E) GTP BINDING
AT1G20970Predicted

interaction prediction

FSW = 0.1191

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN PLASMA MEMBRANE VACUOLE EXPRESSED IN GUARD CELL CULTURED CELL BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS PPI1 (PROTON PUMP INTERACTOR 1) PROTEIN BINDING (TAIRAT4G275001) HAS 53409 BLAST HITS TO 33585 PROTEINS IN 1572 SPECIES ARCHAE - 464 BACTERIA - 7066 METAZOA - 25076 FUNGI - 5173 PLANTS - 1740 VIRUSES - 257 OTHER EUKARYOTES - 13633 (SOURCE NCBI BLINK)
AT2G17800

Predicted

Phenotypic Suppression

FSW = 0.0329

Unknown

ARAC1 GTP BINDING
AT4G29340

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.2759

Unknown

PRF4 (PROFILIN 4) ACTIN BINDING
AT1G31810

Predicted

Phenotypic Enhancement

FSW = 0.1071

Unknown

ACTIN BINDING
AT1G13180

Predicted

two hybrid

two hybrid

Enriched domain pair

Co-expression

FSW = 0.0299

Unknown

DIS1 (DISTORTED TRICHOMES 1) ATP BINDING / ACTIN BINDING / PROTEIN BINDING / STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT4G28820

Predicted

two hybrid

two hybrid

FSW = 0.0395

Unknown

ZINC FINGER (HIT TYPE) FAMILY PROTEIN
AT5G06150

Predicted

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.0184

Unknown

CYC1BAT CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT3G27000

Predicted

Synthetic Lethality

FSW = 0.0298

Unknown

ARP2 (ACTIN RELATED PROTEIN 2) PROTEIN BINDING / STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT3G56640

Predicted

Synthetic Lethality

FSW = 0.0729

Unknown

EXOCYST COMPLEX SUBUNIT SEC15-LIKE FAMILY PROTEIN
AT3G60860

Predicted

Synthetic Lethality

FSW = 0.0165

Unknown

GUANINE NUCLEOTIDE EXCHANGE FAMILY PROTEIN
AT4G34490

Predicted

interaction prediction

interologs mapping

Affinity Capture-Western

two hybrid

Synthetic Rescue

FSW = 0.0855

Unknown

ATCAP1 (ARABIDOPSIS THALIANA CYCLASE ASSOCIATED PROTEIN 1) ACTIN BINDING
AT5G07760Predicted

two hybrid

interologs mapping

two hybrid

FSW = 0.0584

Unknown

FORMIN HOMOLOGY 2 DOMAIN-CONTAINING PROTEIN / FH2 DOMAIN-CONTAINING PROTEIN
AT5G09350

Predicted

Synthetic Lethality

FSW = 0.1763

Unknown

PI-4KBETA2 (PHOSPHATIDYLINOSITOL 4-OH KINASE BETA2) BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR
AT5G19610

Predicted

interologs mapping

FSW = 0.0312

Unknown

SEC7 DOMAIN-CONTAINING PROTEIN
AT4G38470Predicted

Phenotypic Enhancement

FSW = 0.0324

Unknown

PROTEIN KINASE FAMILY PROTEIN
AT5G07780

Predicted

interaction prediction

FSW = 0.0315

Unknown

FORMIN HOMOLOGY 2 DOMAIN-CONTAINING PROTEIN / FH2 DOMAIN-CONTAINING PROTEIN

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454