Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT2G47510 - ( FUM1 (FUMARASE 1) catalytic/ fumarate hydratase )
58 Proteins interacs with AT2G47510| Locus | Method | FSW  | Cellular Compartment Classification (C3) | Description |
|---|---|---|---|---|
AT1G78300
   | Experimental | FSW = 0.0039
| Class B:vacuoleplasma membraneperoxisomenucleusmitochondrioncytosolcytoskeleton | GRF2 (GENERAL REGULATORY FACTOR 2) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING |
| AT3G16480
| PredictedAffinity Capture-MS | FSW = 0.0097
| Class C:mitochondrion | MPPALPHA (MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT) CATALYTIC/ METAL ION BINDING / METALLOENDOPEPTIDASE/ ZINC ION BINDING |
| AT3G47520
| Predictedinterologs mapping | FSW = 0.0353
| Class C:mitochondrion | MDH (MALATE DEHYDROGENASE) L-MALATE DEHYDROGENASE/ BINDING / CATALYTIC/ MALATE DEHYDROGENASE/ OXIDOREDUCTASE/ OXIDOREDUCTASE ACTING ON THE CH-OH GROUP OF DONORS NAD OR NADP AS ACCEPTOR |
| AT4G37910
| Predictedpull down | FSW = 0.0118
| Class C:mitochondrion | MTHSC70-1 (MITOCHONDRIAL HEAT SHOCK PROTEIN 70-1) ATP BINDING |
| AT4G28390
| PredictedAffinity Capture-MS | FSW = 0.0633
| Class C:mitochondrion | AAC3 (ADP/ATP CARRIER 3) ATPADP ANTIPORTER/ BINDING |
| AT4G33650
| PredictedAffinity Capture-MS | FSW = 0.0211
| Class C:mitochondrion | DRP3A (DYNAMIN-RELATED PROTEIN 3A) GTP BINDING / GTPASE/ PHOSPHOINOSITIDE BINDING |
| AT4G33760
| Predictedpull down | FSW = 0.0342
| Class C:mitochondrion | TRNA SYNTHETASE CLASS II (D K AND N) FAMILY PROTEIN |
| AT1G53530
| Predictedsynthetic growth defect | FSW = 0.1318
| Class C:mitochondrion | SIGNAL PEPTIDASE I FAMILY PROTEIN |
| AT1G53240
| Predictedin vitroAffinity Capture-MS | FSW = 0.0207
| Class C:mitochondrion | MALATE DEHYDROGENASE (NAD) MITOCHONDRIAL |
| AT5G50950
| PredictedPhylogenetic profile method | FSW = 0.0645
| Class C:mitochondrion | FUMARATE HYDRATASE PUTATIVE / FUMARASE PUTATIVE |
| AT5G66760
| Predictedpull down | FSW = 0.0062
| Class C:mitochondrion | SDH1-1 ATP BINDING / SUCCINATE DEHYDROGENASE |
| AT3G09630
| PredictedAffinity Capture-MS | FSW = 0.0185
| Unknown | 60S RIBOSOMAL PROTEIN L4/L1 (RPL4A) |
| AT2G37270
| PredictedSynthetic Lethality | FSW = 0.0622
| Unknown | ATRPS5B (RIBOSOMAL PROTEIN 5B) STRUCTURAL CONSTITUENT OF RIBOSOME |
| AT3G08710
| PredictedAffinity Capture-MS | FSW = 0.0079
| Unknown | ATH9 (THIOREDOXIN H-TYPE 9) |
| AT3G13080
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-Western | FSW = 0.0637
| Unknown | ATMRP3 ATPASE COUPLED TO TRANSMEMBRANE MOVEMENT OF SUBSTANCES / CHLOROPHYLL CATABOLITE TRANSPORTER/ GLUTATHIONE S-CONJUGATE-EXPORTING ATPASE |
| AT5G16150
| Predictedtwo hybrid | FSW = 0.0212
| Unknown | PGLCT (PLASTIDIC GLC TRANSLOCATOR) CARBOHYDRATE TRANSMEMBRANE TRANSPORTER/ SUGARHYDROGEN SYMPORTER |
| AT5G42270
| Predictedpull down | FSW = 0.0101
| Unknown | VAR1 (VARIEGATED 1) ATP-DEPENDENT PEPTIDASE/ ATPASE/ METALLOPEPTIDASE |
| AT1G19660
| PredictedAffinity Capture-MSAffinity Capture-MSSynthetic LethalityAffinity Capture-WesternAffinity Capture-MSAffinity Capture-Westerntwo hybridtwo hybridReconstituted ComplexAffinity Capture-MSAffinity Capture-Westerninterologs mapping | FSW = 0.1086
| Unknown | WOUND-RESPONSIVE FAMILY PROTEIN |
| AT5G53480
| PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.0464
| Unknown | IMPORTIN BETA-2 PUTATIVE |
| ATCG00830 | Predictedpull down | FSW = 0.0088
| Unknown | ENCODES A CHLOROPLAST RIBOSOMAL PROTEIN L2 A CONSTITUENT OF THE LARGE SUBUNIT OF THE RIBOSOMAL COMPLEX |
| AT2G45710
| PredictedAffinity Capture-WesternAffinity Capture-MSSynthetic LethalityAffinity Capture-WesternAffinity Capture-MSAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSAffinity Capture-WesternAffinity Capture-MSinterologs mapping | FSW = 0.3068
| Unknown | 40S RIBOSOMAL PROTEIN S27 (RPS27A) |
| AT5G63680
| Predictedpull down | FSW = 0.0167
| Unknown | PYRUVATE KINASE PUTATIVE |
| AT1G55690
| Predictedtwo hybrid | FSW = 0.0382
| Unknown | SEC14 CYTOSOLIC FACTOR FAMILY PROTEIN / PHOSPHOGLYCERIDE TRANSFER FAMILY PROTEIN |
| AT2G36380
| PredictedAffinity Capture-MS | FSW = 0.0085
| Unknown | PDR6 ATPASE COUPLED TO TRANSMEMBRANE MOVEMENT OF SUBSTANCES |
| AT3G19930
| PredictedAffinity Capture-MS | FSW = 0.0054
| Unknown | STP4 (SUGAR TRANSPORTER 4) CARBOHYDRATE TRANSMEMBRANE TRANSPORTER/ MONOSACCHARIDE TRANSMEMBRANE TRANSPORTER/ SUCROSEHYDROGEN SYMPORTER/ SUGARHYDROGEN SYMPORTER |
| AT1G13320
| PredictedAffinity Capture-MS | FSW = 0.0182
| Unknown | PP2AA3 (PROTEIN PHOSPHATASE 2A SUBUNIT A3) BINDING / PROTEIN PHOSPHATASE TYPE 2A REGULATOR |
| AT5G22770
| PredictedAffinity Capture-MS | FSW = 0.0161
| Unknown | ALPHA-ADR (ALPHA-ADAPTIN) BINDING / PROTEIN BINDING / PROTEIN TRANSPORTER |
| AT2G43810
| PredictedAffinity Capture-MS | FSW = 0.0071
| Unknown | SMALL NUCLEAR RIBONUCLEOPROTEIN F PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE / SM PROTEIN F PUTATIVE |
| AT4G34430
| PredictedAffinity Capture-MS | FSW = 0.0145
| Unknown | CHB3 DNA BINDING / TRANSCRIPTION FACTOR/ ZINC ION BINDING |
| AT3G52250
| Predictedinterologs mappingSynthetic Rescue | FSW = 0.0252
| Unknown | DNA BINDING / TRANSCRIPTION FACTOR |
| AT2G14610
| PredictedAffinity Capture-MSAffinity Capture-MSSynthetic LethalityAffinity Capture-MSAffinity Capture-MSReconstituted Complextwo hybridco-fractionationCo-fractionationinterologs mapping | FSW = 0.1690
| Unknown | PR1 (PATHOGENESIS-RELATED GENE 1) |
| AT2G03120
| PredictedAffinity Capture-MS | FSW = 0.0216
| Unknown | ATSPP (ARABIDOPSIS SIGNAL PEPTIDE PEPTIDASE) ASPARTIC-TYPE ENDOPEPTIDASE |
| AT3G05210
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0073
| Unknown | ERCC1 5-FLAP ENDONUCLEASE |
| AT3G22880
| PredictedAffinity Capture-MS | FSW = 0.0077
| Unknown | DMC1 (DISRUPTION OF MEIOTIC CONTROL 1) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING |
| AT1G32380
| Predictedpull down | FSW = 0.0142
| Unknown | RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 / PHOSPHORIBOSYL DIPHOSPHATE SYNTHETASE 2 (PRS2) |
| AT1G01560
| PredictedAffinity Capture-MS | FSW = 0.0219
| Unknown | ATMPK11 MAP KINASE/ KINASE |
| AT1G12340
| PredictedAffinity Capture-MS | FSW = 0.0254
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN INTRACELLULAR SIGNALING CASCADE LOCATED IN MEMBRANE EXPRESSED IN MALE GAMETOPHYTE POLLEN TUBE EXPRESSED DURING L MATURE POLLEN STAGE M GERMINATED POLLEN STAGE CONTAINS INTERPRO DOMAIN/S CORNICHON (INTERPROIPR003377) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS CORNICHON FAMILY PROTEIN (TAIRAT1G123901) HAS 463 BLAST HITS TO 463 PROTEINS IN 125 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 278 FUNGI - 110 PLANTS - 41 VIRUSES - 0 OTHER EUKARYOTES - 34 (SOURCE NCBI BLINK) |
| AT1G15440
| PredictedAffinity Capture-MS | FSW = 0.0417
| Unknown | TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN |
| AT1G26140
| PredictedAffinity Capture-MS | FSW = 0.0516
| Unknown | UNKNOWN PROTEIN |
| AT1G30220
| PredictedAffinity Capture-MS | FSW = 0.0275
| Unknown | INT2 (INOSITOL TRANSPORTER 2) CARBOHYDRATE TRANSMEMBRANE TRANSPORTER/ SUGARHYDROGEN SYMPORTER |
| AT2G32220
| Predictedsynthetic growth defectinterologs mappingsynthetic growth defect | FSW = 0.0955
| Unknown | 60S RIBOSOMAL PROTEIN L27 (RPL27A) |
| AT2G39590
| PredictedAffinity Capture-MS | FSW = 0.0142
| Unknown | 40S RIBOSOMAL PROTEIN S15A (RPS15AC) |
| AT3G62770
| PredictedSynthetic LethalitySynthetic LethalitySynthetic Lethality | FSW = 0.0429
| Unknown | ATATG18A |
| AT4G19880
| PredictedAffinity Capture-MSAffinity Capture-WesternAffinity Capture-MSSynthetic LethalityAffinity Capture-MSinterologs mappingAffinity Capture-MSAffinity Capture-Western | FSW = 0.0725
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN RESPONSE TO CADMIUM ION LOCATED IN CHLOROPLAST EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S GLUTATHIONE S-TRANSFERASE PREDICTED (INTERPROIPR016639) GLUTATHIONE S-TRANSFERASE C-TERMINAL (INTERPROIPR004046) GLUTATHIONE S-TRANSFERASE C-TERMINAL-LIKE (INTERPROIPR010987) GLUTATHIONE S-TRANSFERASE/CHLORIDE CHANNEL C-TERMINAL (INTERPROIPR017933) THIOREDOXIN-LIKE FOLD (INTERPROIPR012336) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT5G450201) HAS 1635 BLAST HITS TO 1635 PROTEINS IN 489 SPECIES ARCHAE - 12 BACTERIA - 905 METAZOA - 23 FUNGI - 158 PLANTS - 57 VIRUSES - 0 OTHER EUKARYOTES - 480 (SOURCE NCBI BLINK) |
| AT3G06470
| Predictedinterologs mapping | FSW = 0.0152
| Unknown | GNS1/SUR4 MEMBRANE FAMILY PROTEIN |
| AT3G09640
| PredictedAffinity Capture-MS | FSW = 0.0200
| Unknown | APX2 (ASCORBATE PEROXIDASE 2) L-ASCORBATE PEROXIDASE |
| AT3G15470
| PredictedAffinity Capture-MS | FSW = 0.0391
| Unknown | WD-40 REPEAT FAMILY PROTEIN |
| AT3G22860
| PredictedAffinity Capture-MS | FSW = 0.0057
| Unknown | TIF3C2 TRANSLATION INITIATION FACTOR |
| AT3G24830
| PredictedAffinity Capture-MS | FSW = 0.0145
| Unknown | 60S RIBOSOMAL PROTEIN L13A (RPL13AB) |
| AT3G60245
| PredictedSynthetic Lethality | FSW = 0.1233
| Unknown | 60S RIBOSOMAL PROTEIN L37A (RPL37AC) |
| AT4G04210
| PredictedAffinity Capture-MS | FSW = 0.0203
| Unknown | PUX4 PROTEIN BINDING |
| AT4G04955
| PredictedAffinity Capture-MS | FSW = 0.0131
| Unknown | ATALN (ARABIDOPSIS ALLANTOINASE) ALLANTOINASE/ HYDROLASE |
| AT4G10360
| PredictedAffinity Capture-MS | FSW = 0.0363
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN INTEGRAL TO MEMBRANE EXPRESSED IN 24 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S TRAM LAG1 AND CLN8 HOMOLOGY (INTERPROIPR006634) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT1G313002) HAS 453 BLAST HITS TO 451 PROTEINS IN 101 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 225 FUNGI - 97 PLANTS - 91 VIRUSES - 3 OTHER EUKARYOTES - 37 (SOURCE NCBI BLINK) |
| AT4G13020
| PredictedAffinity Capture-MS | FSW = 0.0092
| Unknown | MHK ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE |
| AT4G22753
| PredictedAffinity Capture-MS | FSW = 0.0164
| Unknown | SMO1-3 (STEROL 4-ALPHA METHYL OXIDASE 1-3) 44-DIMETHYL-9BETA19-CYCLOPROPYLSTEROL-4ALPHA-METHYL OXIDASE/ CATALYTIC |
| AT4G24160
| PredictedAffinity Capture-MS | FSW = 0.0124
| Unknown | HYDROLASE ALPHA/BETA FOLD FAMILY PROTEIN |
| AT5G24840
| PredictedAffinity Capture-MS | FSW = 0.0311
| Unknown | TRNA (GUANINE-N7-)-METHYLTRANSFERASE |
| AT5G39400
| PredictedAffinity Capture-MS | FSW = 0.0299
| Unknown | PTEN1 PHOSPHATASE |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
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