Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT3G61650 - ( TUBG1 (GAMMA-TUBULIN) GTP binding / GTPase/ structural molecule )

33 Proteins interacs with AT3G61650
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G12580

Predicted

Synthetic Lethality

FSW = 0.0257

Class C:

plasma membrane

mitochondrion

HSP70 (HEAT SHOCK PROTEIN 70) ATP BINDING
AT4G14960

Predicted

Phenotypic Suppression

Synthetic Rescue

FSW = 0.1498

Class C:

plasma membrane

cytoskeleton

TUA6 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT5G06680

Predicted

interaction prediction

two hybrid

two hybrid

two hybrid

Synthetic Lethality

interologs mapping

interologs mapping

interologs mapping

Co-purification

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

in vivo

FSW = 0.1800

Class C:

plasma membrane

cytoskeleton

SPC98 (SPINDLE POLE BODY COMPONENT 98) TUBULIN BINDING
AT5G12250

Predicted

Shared biological function

Enriched domain pair

Phylogenetic profile method

FSW = 0.3105

Class C:

plasma membrane

cytoskeleton

TUB6 (BETA-6 TUBULIN) STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT1G20010

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.2768

Class C:

plasma membrane

TUB5 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT2G29550

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.4386

Class C:

plasma membrane

TUB7 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT4G20890

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.4676

Class C:

plasma membrane

TUB9 GTP BINDING / GTPASE/ STRUCTURAL MOLECULE
AT5G62690

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.3478

Class C:

plasma membrane

TUB2 GTP BINDING / GTPASE/ STRUCTURAL MOLECULE
AT3G44110

Predicted

Synthetic Lethality

FSW = 0.0432

Class C:

plasma membrane

ATJ3 PROTEIN BINDING
AT1G16030

Predicted

Synthetic Lethality

FSW = 0.0419

Class C:

plasma membrane

HSP70B (HEAT SHOCK PROTEIN 70B) ATP BINDING
AT5G22060

Predicted

Synthetic Lethality

FSW = 0.0657

Class C:

plasma membrane

ATJ2 PROTEIN BINDING
AT5G23860

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.4676

Class C:

plasma membrane

TUB8 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT5G44340

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.4676

Class C:

plasma membrane

TUB4 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT3G43810

Predicted

Affinity Capture-Western

interologs mapping

FSW = 0.0161

Class C:

plasma membrane

CAM7 (CALMODULIN 7) CALCIUM ION BINDING
AT1G66410

Predicted

Affinity Capture-Western

interologs mapping

FSW = 0.0181

Class C:

plasma membrane

CAM4 (CALMODULIN 4) CALCIUM ION BINDING / SIGNAL TRANSDUCER
AT5G05620

Predicted

Shared biological function

Enriched domain pair

Gene fusion method

Phylogenetic profile method

FSW = 0.3827

Class C:

mitochondrion

cytoskeleton

GCP2 (GAMMA-TUBULIN COMPLEX PROTEIN 2) GTP BINDING / GTPASE/ STRUCTURAL MOLECULE
AT4G05190

Predicted

Reconstituted Complex

Enriched domain pair

FSW = 0.1346

Class C:

cytoskeleton

ATK5 (ARABIDOPSIS THALIANA KINESIN 5) MICROTUBULE MOTOR
AT5G67270

Predicted

Synthetic Lethality

interologs mapping

FSW = 0.1010

Class C:

cytoskeleton

ATEB1C (MICROTUBULE END BINDING PROTEIN 1) MICROTUBULE BINDING
AT1G75780

Predicted

Shared biological function

Enriched domain pair

Phylogenetic profile method

FSW = 0.4302

Unknown

TUB1 GTP BINDING / GTPASE/ STRUCTURAL MOLECULE
AT3G25980

Predicted

Synthetic Lethality

Colocalization

FSW = 0.1280

Unknown

MITOTIC SPINDLE CHECKPOINT PROTEIN PUTATIVE (MAD2)
AT1G08780

Predicted

interaction prediction

Synthetic Lethality

Affinity Capture-Western

interologs mapping

FSW = 0.0864

Unknown

AIP3 (ABI3-INTERACTING PROTEIN 3) UNFOLDED PROTEIN BINDING
AT1G29990

Predicted

interaction prediction

Synthetic Lethality

interologs mapping

Affinity Capture-Western

FSW = 0.1432

Unknown

PDF6 (PREFOLDIN 6) UNFOLDED PROTEIN BINDING
AT2G22480

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0583

Unknown

PFK5 (PHOSPHOFRUCTOKINASE 5) 6-PHOSPHOFRUCTOKINASE
AT1G30825

Predicted

interologs mapping

FSW = 0.0777

Unknown

DIS2 (DISTORTED TRICHOMES 2) STRUCTURAL MOLECULE
AT2G23070

Predicted

interologs mapping

FSW = 0.0316

Unknown

CASEIN KINASE II ALPHA CHAIN PUTATIVE
AT3G22480

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.1021

Unknown

PREFOLDIN-RELATED KE2 FAMILY PROTEIN
AT4G27180

Predicted

Reconstituted Complex

FSW = 0.2149

Unknown

ATK2 (ARABIDOPSIS THALIANA KINESIN 2) MICROTUBULE BINDING / MICROTUBULE MOTOR
AT5G17410

Predicted

two hybrid

two hybrid

Reconstituted Complex

interologs mapping

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-Western

two hybrid

two hybrid

Affinity Capture-MS

Synthetic Rescue

interaction prediction

FSW = 0.1810

Unknown

TUBULIN FAMILY PROTEIN
AT5G23290

Predicted

interaction prediction

Synthetic Lethality

Affinity Capture-Western

FSW = 0.1104

Unknown

PDF5 (PREFOLDIN 5) UNFOLDED PROTEIN BINDING
AT5G49510

Predicted

Synthetic Lethality

Affinity Capture-Western

interaction prediction

FSW = 0.0852

Unknown

PDF3 (PREFOLDIN 3) UNFOLDED PROTEIN BINDING
AT4G39050

Predicted

Synthetic Lethality

FSW = 0.3135

Unknown

KINESIN-RELATED PROTEIN (MKRP2)
AT3G49650

Predicted

Synthetic Lethality

FSW = 0.1241

Unknown

KINESIN MOTOR PROTEIN-RELATED
AT5G62700Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.2846

Unknown

TUB3 GTP BINDING / GTPASE/ STRUCTURAL MOLECULE

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454