Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT4G26070 - ( MEK1 (MAP KINASE/ ERK KINASE 1) MAP kinase kinase/ kinase/ protein binding )

24 Proteins interacs with AT4G26070
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT4G01370

Experimental

two hybrid

protein kinase assay

protein complementation assay

split-reporter assay

two hybrid

FSW = 0.0718

Unknown

ATMPK4 (ARABIDOPSIS THALIANA MAP KINASE 4) MAP KINASE/ KINASE
AT1G35160

Experimental

pull down

FSW = 0.0257

Unknown

GF14 PHI (GF14 PROTEIN PHI CHAIN) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING
AT4G08500

Experimental

two hybrid

two hybrid

coimmunoprecipitation

two hybrid

protein complementation assay

coimmunoprecipitation

split-reporter assay

FSW = 0.0320

Unknown

MEKK1 (MAP KINASE KINASE KINASE 1) DNA BINDING / MAP KINASE KINASE KINASE/ KINASE/ KINASE BINDING / PROTEIN BINDING
AT2G46070

Experimental

protein kinase assay

FSW = 0.0913

Unknown

MPK12 (MITOGEN-ACTIVATED PROTEIN KINASE 12) MAP KINASE/ KINASE
AT1G01560

Experimental

protein kinase assay

FSW = 0.1576

Unknown

ATMPK11 MAP KINASE/ KINASE
AT4G37930

Predicted

Affinity Capture-MS

FSW = 0.0228

Unknown

SHM1 (SERINE TRANSHYDROXYMETHYLTRANSFERASE 1) GLYCINE HYDROXYMETHYLTRANSFERASE/ POLY(U) BINDING
AT4G29810

Predicted

Shared biological function

Phylogenetic profile method

Co-expression

FSW = 0.3350

Unknown

ATMKK2 (ARABIDOPSIS THALIANA MAP KINASE KINASE 2) MAP KINASE KINASE/ KINASE
AT1G10900

Predicted

interologs mapping

FSW = 0.0228

Unknown

PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE FAMILY PROTEIN
AT2G19480

Predicted

Affinity Capture-MS

FSW = 0.0280

Unknown

NAP12 (NUCLEOSOME ASSEMBLY PROTEIN 12) DNA BINDING
AT1G24180

Predicted

Affinity Capture-MS

FSW = 0.0247

Unknown

IAR4 OXIDOREDUCTASE ACTING ON THE ALDEHYDE OR OXO GROUP OF DONORS DISULFIDE AS ACCEPTOR / PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)
AT1G43900

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

FSW = 0.0883

Unknown

PROTEIN PHOSPHATASE 2C PUTATIVE / PP2C PUTATIVE
AT5G02530

Predicted

Affinity Capture-MS

FSW = 0.0190

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT4G12600

Predicted

Affinity Capture-MS

FSW = 0.0476

Unknown

RIBOSOMAL PROTEIN L7AE/L30E/S12E/GADD45 FAMILY PROTEIN
AT2G43790

Predicted

in vivo

in vivo

in vitro

in vitro

Affinity Capture-Western

in vitro

in vivo

Shared biological function

Co-expression

FSW = 0.1528

Unknown

ATMPK6 (ARABIDOPSIS THALIANA MAP KINASE 6) MAP KINASE/ KINASE
AT5G17930

Predicted

interologs mapping

FSW = 0.1254

Unknown

BINDING / PROTEIN BINDING
AT3G45640

Predicted

two hybrid

two hybrid

in vivo

in vivo

in vitro

in vitro

in vitro

in vivo

two hybrid

Shared biological function

Co-expression

FSW = 0.1408

Unknown

ATMPK3 (ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE 3) MAP KINASE/ KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT4G08470

Predicted

in vitro

in vivo

Co-expression

FSW = 0.0298

Unknown

MAPKKK10 ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT1G66620

Predicted

in vitro

in vivo

FSW = 0.1607

Unknown

SEVEN IN ABSENTIA (SINA) PROTEIN PUTATIVE
AT3G01090

Predicted

Phenotypic Enhancement

FSW = 0.0278

Unknown

AKIN10 (ARABIDOPSIS SNF1 KINASE HOMOLOG 10) PROTEIN BINDING / PROTEIN KINASE
AT1G27320

Predicted

Phenotypic Suppression

FSW = 0.0347

Unknown

AHK3 (ARABIDOPSIS HISTIDINE KINASE 3) CYTOKININ RECEPTOR/ OSMOSENSOR/ PROTEIN HISTIDINE KINASE
AT1G67070

Predicted

synthetic growth defect

FSW = 0.0756

Unknown

DIN9 (DARK INDUCIBLE 9) MANNOSE-6-PHOSPHATE ISOMERASE
AT1G18350

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.2294

Unknown

ATMKK7 MAP KINASE KINASE/ KINASE
AT3G06230

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.1589

Unknown

ATMKK8 MAP KINASE KINASE/ KINASE
AT5G56580

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.2118

Unknown

MKK6 (MAP KINASE KINASE 6) MAP KINASE KINASE/ KINASE

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454