Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT4G34570 - ( THY-2 (thymidylate synthase 2) dihydrofolate reductase/ thymidylate synthase )

10 Proteins interacs with AT4G34570
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G02920

Predicted

Affinity Capture-MS

FSW = 0.0697

Unknown

GSTF7 COPPER ION BINDING / GLUTATHIONE BINDING / GLUTATHIONE TRANSFERASE
AT5G55400

Predicted

Phenotypic Enhancement

FSW = 0.0373

Unknown

FIMBRIN-LIKE PROTEIN PUTATIVE
ATCG00830Predicted

pull down

FSW = 0.0109

Unknown

ENCODES A CHLOROPLAST RIBOSOMAL PROTEIN L2 A CONSTITUENT OF THE LARGE SUBUNIT OF THE RIBOSOMAL COMPLEX
AT3G10330

Predicted

interaction prediction

FSW = 0.0157

Unknown

TRANSCRIPTION INITIATION FACTOR IIB-2 / GENERAL TRANSCRIPTION FACTOR TFIIB-2 (TFIIB2)
AT3G12810

Predicted

Synthetic Lethality

FSW = 0.0308

Unknown

PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT2G36740

Predicted

Synthetic Lethality

FSW = 0.0454

Unknown

SWC2 DNA BINDING / TRANSCRIPTION FACTOR
AT1G50920

Predicted

interaction prediction

FSW = 0.0122

Unknown

GTP-BINDING PROTEIN-RELATED
AT5G37530

Predicted

pull down

FSW = 0.0618

Unknown

THIF FAMILY PROTEIN
AT1G61040

Predicted

Affinity Capture-MS

FSW = 0.0429

Unknown

VIP5 (VERNALIZATION INDEPENDENCE 5) DNA BINDING
AT2G21550

Predicted

Enriched domain pair

Phylogenetic profile method

FSW = 0.0462

Unknown

BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE PUTATIVE / DHFR-TS PUTATIVE

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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454