Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G20320 - ( DCL4 (DICER-LIKE 4) RNA binding / protein binding / ribonuclease III )

7 Proteins interacs with AT5G20320
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G62800

Experimental

affinity technology

far western blotting

Affinity Capture-Western

Reconstituted Complex

FSW = 0.1025

Class A:

nucleus

Class D:

nucleus (p = 0.78)

 DRB4 (DOUBLE-STRANDED-RNA-BINDING PROTEIN 4) DOUBLE-STRANDED RNA BINDING / PROTEIN BINDING
AT3G03300

Predicted

Shared biological function

Enriched domain pair

Co-expression

FSW = 0.4635

Class C:

nucleus

 DCL2 (DICER-LIKE 2) ATP BINDING / ATP-DEPENDENT HELICASE/ RNA BINDING / DOUBLE-STRANDED RNA BINDING / HELICASE/ NUCLEIC ACID BINDING / RIBONUCLEASE III
AT3G43920

Predicted

Shared biological function

Co-expression

FSW = 0.1303

Class C:

nucleus

 RIBONUCLEASE III FAMILY PROTEIN
AT1G01040

Predicted

Shared biological function

Enriched domain pair

Co-expression

FSW = 0.2939

Class C:

nucleus

 DCL1 (DICER-LIKE 1) ATP-DEPENDENT HELICASE/ DOUBLE-STRANDED RNA BINDING / PROTEIN BINDING / RIBONUCLEASE III
AT5G47010

Predicted

Shared biological function

Co-expression

FSW = 0.1412

Unknown

 LBA1 (LOW-LEVEL BETA-AMYLASE 1) ATP BINDING / DNA BINDING / RNA HELICASE/ HYDROLASE
AT1G48410

Predicted

Shared biological function

Co-expression

FSW = 0.5414

Unknown

 AGO1 (ARGONAUTE 1) ENDORIBONUCLEASE/ MIRNA BINDING / PROTEIN BINDING / SIRNA BINDING
AT1G69440

Predicted

Shared biological function

Co-expression

FSW = 0.3401

Unknown

 AGO7 (ARGONAUTE7) NUCLEIC ACID BINDING

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454

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