Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G22010 - ( AtRFC1 (replication factor C 1) ATP binding / DNA binding / DNA clamp loader/ nucleoside-triphosphatase/ nucleotide binding )

36 Proteins interacs with AT5G22010
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G07660Predicted

Affinity Capture-MS

FSW = 0.0555

Unknown

HISTONE H4
AT4G01370

Predicted

Phenotypic Enhancement

FSW = 0.0316

Unknown

ATMPK4 (ARABIDOPSIS THALIANA MAP KINASE 4) MAP KINASE/ KINASE
AT3G02520

Predicted

Phenotypic Enhancement

FSW = 0.0175

Unknown

GRF7 (GENERAL REGULATORY FACTOR 7) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING
AT5G59690Predicted

Affinity Capture-MS

FSW = 0.0635

Unknown

HISTONE H4
AT3G48190

Predicted

Co-purification

FSW = 0.2660

Unknown

ATM (ATAXIA-TELANGIECTASIA MUTATED) 1-PHOSPHATIDYLINOSITOL-3-PHOSPHATE 5-KINASE
AT3G18524

Predicted

Phenotypic Enhancement

Co-purification

FSW = 0.2519

Unknown

MSH2 (MUTS HOMOLOG 2) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT1G08130

Predicted

Affinity Capture-Western

FSW = 0.3467

Unknown

ATLIG1 (ARABIDOPSIS THALIANA DNA LIGASE 1) ATP BINDING / DNA BINDING / DNA LIGASE (ATP)
AT4G02070

Predicted

Co-purification

FSW = 0.2900

Unknown

MSH6 (MUTS HOMOLOG 6) DAMAGED DNA BINDING
AT1G21690

Predicted

two hybrid

Synthetic Lethality

Co-purification

Co-purification

Co-purification

Co-purification

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.3575

Unknown

EMB1968 (EMBRYO DEFECTIVE 1968) ATP BINDING / ATPASE/ DNA BINDING / DNA CLAMP LOADER/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT4G38130

Predicted

Affinity Capture-Western

Reconstituted Complex

in vitro

in vivo

FSW = 0.0349

Unknown

HD1 (HISTONE DEACETYLASE 1) BASAL TRANSCRIPTION REPRESSOR/ HISTONE DEACETYLASE/ PROTEIN BINDING
AT2G29570

Predicted

in vivo

in vivo

in vivo

in vitro

in vitro

in vitro

two hybrid

FSW = 0.1788

Unknown

PCNA2 (PROLIFERATING CELL NUCLEAR ANTIGEN 2) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR
AT1G07370

Predicted

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Lethality

Synthetic Lethality

Synthetic Lethality

Reconstituted Complex

two hybrid

interaction prediction

FSW = 0.2653

Unknown

PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING
AT2G13370

Predicted

Phenotypic Enhancement

FSW = 0.0677

Unknown

CHR5 (CHROMATIN REMODELING 5) ATP BINDING / DNA BINDING / CHROMATIN BINDING / HELICASE/ NUCLEIC ACID BINDING
AT4G08350

Predicted

Affinity Capture-MS

FSW = 0.0163

Unknown

GTA2 (GLOBAL TRANSCRIPTION FACTOR GROUP A2) STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION FACTOR
AT2G34210

Predicted

Affinity Capture-MS

FSW = 0.0159

Unknown

STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION INITIATION FACTOR
AT1G06230

Predicted

in vitro

in vivo

FSW = 0.1015

Unknown

GTE4 (GLOBAL TRANSCRIPTION FACTOR GROUP E 4) DNA BINDING
AT1G67630

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0850

Unknown

POLA2 (DNA POLYMERASE ALPHA 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE
AT2G31970

Predicted

Co-purification

FSW = 0.1464

Unknown

RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING
AT5G66130

Predicted

Phenotypic Enhancement

Affinity Capture-Western

interologs mapping

FSW = 0.2039

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT5G63960

Predicted

Synthetic Lethality

in vivo

in vitro

FSW = 0.1321

Unknown

EMB2780 (EMBRYO DEFECTIVE 2780) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING
AT4G26840

Predicted

Affinity Capture-MS

FSW = 0.0035

Unknown

SUMO1 (SMALL UBIQUITIN-LIKE MODIFIER 1) PROTEIN BINDING / PROTEIN TAG
AT5G54260

Predicted

Co-purification

Phenotypic Enhancement

FSW = 0.1498

Unknown

MRE11 (MEIOTIC RECOMBINATION 11) ENDONUCLEASE/ EXONUCLEASE/ HYDROLASE/ MANGANESE ION BINDING / PROTEIN SERINE/THREONINE PHOSPHATASE
AT5G27740

Predicted

two hybrid

Synthetic Rescue

in vivo

in vivo

in vitro

in vitro

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Synthetic Rescue

Affinity Capture-MS

interaction prediction

FSW = 0.1852

Unknown

EMB2775 (EMBRYO DEFECTIVE 2775) DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT1G10930

Predicted

Phenotypic Enhancement

Co-purification

FSW = 0.0847

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT3G02680

Predicted

Co-purification

FSW = 0.3202

Unknown

NBS1 (NIJMEGEN BREAKAGE SYNDROME 1)
AT3G05740

Predicted

Co-purification

FSW = 0.2300

Unknown

RECQI1 (ARABIDOPSIS RECQ HELICASE L1) ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT4G09140

Predicted

Co-purification

FSW = 0.2458

Unknown

MLH1 (MUTL-HOMOLOGUE 1) PROTEIN BINDING BRIDGING
AT1G08880

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0527

Unknown

H2AXA DNA BINDING
AT1G63160

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.2760

Unknown

REPLICATION FACTOR C 40 KDA PUTATIVE
AT1G77470

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.2799

Unknown

REPLICATION FACTOR C 36 KDA PUTATIVE
AT2G44150

Predicted

Phenotypic Enhancement

FSW = 0.0374

Unknown

ASHH3 (HISTONE-LYSINE N-METHYLTRANSFERASE ASHH3) HISTONE-LYSINE N-METHYLTRANSFERASE
AT3G21060

Predicted

Phenotypic Enhancement

FSW = 0.0290

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT4G02460

Predicted

Phenotypic Enhancement

FSW = 0.2107

Unknown

PMS1 (POSTMEIOTIC SEGREGATION 1) ATP BINDING / MISMATCHED DNA BINDING
AT1G52740

Predicted

synthetic growth defect

FSW = 0.0856

Unknown

HTA9 (HISTONE H2A PROTEIN 9) DNA BINDING
AT1G66740

Predicted

synthetic growth defect

Affinity Capture-Western

FSW = 0.1329

Unknown

SGA2
AT5G26680

Predicted

Synthetic Lethality

FSW = 0.1176

Unknown

ENDONUCLEASE PUTATIVE

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454