Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G22750 - ( RAD5 ATP binding / ATP-dependent helicase/ DNA binding / helicase/ hydrolase acting on acid anhydrides in phosphorus-containing anhydrides / nucleic acid binding / protein binding / zinc ion binding )

44 Proteins interacs with AT5G22750
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT2G15240

Predicted

synthetic growth defect

FSW = 0.0622

Class C:

nucleus

UNC-50 FAMILY PROTEIN
AT1G05120

Predicted

Phenotypic Enhancement

FSW = 0.0261

Class C:

nucleus

SNF2 DOMAIN-CONTAINING PROTEIN / HELICASE DOMAIN-CONTAINING PROTEIN / RING FINGER DOMAIN-CONTAINING PROTEIN
AT2G26150

Predicted

synthetic growth defect

FSW = 0.2775

Class C:

nucleus

ATHSFA2 DNA BINDING / TRANSCRIPTION FACTOR
AT1G07370

Predicted

two hybrid

Phenotypic Enhancement

interologs mapping

Phenotypic Enhancement

two hybrid

FSW = 0.2211

Class C:

nucleus

PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING
AT3G19210

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.3053

Class C:

nucleus

ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT2G46340

Predicted

Gene fusion method

FSW = 0.0450

Class C:

nucleus

SPA1 (SUPPRESSOR OF PHYA-105 1) PROTEIN BINDING / SIGNAL TRANSDUCER
AT1G12520

Predicted

synthetic growth defect

FSW = 0.2350

Unknown

ATCCS (COPPER CHAPERONE FOR SOD1) SUPEROXIDE DISMUTASE/ SUPEROXIDE DISMUTASE COPPER CHAPERONE
AT3G11630

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.1445

Unknown

2-CYS PEROXIREDOXIN CHLOROPLAST (BAS1)
AT1G16890

Predicted

two hybrid

two hybrid

two hybrid

Affinity Capture-Western

Enriched domain pair

FSW = 0.0857

Unknown

UBIQUITIN-CONJUGATING ENZYME PUTATIVE
AT1G35940Predicted

synthetic growth defect

FSW = 0.3659

Unknown

UBIQUITIN-CONJUGATING ENZYME PUTATIVE
AT2G31970

Predicted

synthetic growth defect

Synthetic Lethality

FSW = 0.2643

Unknown

RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING
AT5G41150

Predicted

Phenotypic Enhancement

FSW = 0.1460

Unknown

UVH1 (ULTRAVIOLET HYPERSENSITIVE 1) SINGLE-STRANDED DNA SPECIFIC ENDODEOXYRIBONUCLEASE
AT5G05490

Predicted

synthetic growth defect

FSW = 0.0933

Unknown

SYN1 (SYNAPTIC 1)
AT5G57450

Predicted

synthetic growth defect

FSW = 0.3042

Unknown

XRCC3 ATP BINDING / DAMAGED DNA BINDING / PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
AT3G28030

Predicted

synthetic growth defect

FSW = 0.1463

Unknown

UVH3 (ULTRAVIOLET HYPERSENSITIVE 3) DNA BINDING / CATALYTIC/ ENDONUCLEASE/ NUCLEASE/ SINGLE-STRANDED DNA BINDING
AT3G05210

Predicted

Phenotypic Enhancement

FSW = 0.0919

Unknown

ERCC1 5-FLAP ENDONUCLEASE
AT5G54260

Predicted

synthetic growth defect

FSW = 0.2893

Unknown

MRE11 (MEIOTIC RECOMBINATION 11) ENDONUCLEASE/ EXONUCLEASE/ HYDROLASE/ MANGANESE ION BINDING / PROTEIN SERINE/THREONINE PHOSPHATASE
AT5G20850

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.2323

Unknown

ATRAD51 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING / SEQUENCE-SPECIFIC DNA BINDING
AT1G08830

Predicted

Synthetic Lethality

FSW = 0.3167

Unknown

CSD1 (COPPER/ZINC SUPEROXIDE DISMUTASE 1) SUPEROXIDE DISMUTASE
AT3G05480

Predicted

synthetic growth defect

FSW = 0.0594

Unknown

RAD9
AT5G50680Predicted

Phenotypic Enhancement

FSW = 0.0759

Unknown

SAE1B (SUMO ACTIVATING ENZYME 1B) SUMO ACTIVATING ENZYME
AT5G61460

Predicted

synthetic growth defect

FSW = 0.0417

Unknown

MIM (HYPERSENSITIVE TO MMS IRRADIATION AND MMC) ATP BINDING
AT1G23260

Predicted

Phenotypic Enhancement

Enriched domain pair

Co-expression

FSW = 0.1764

Unknown

MMZ1 (MMS ZWEI HOMOLOGUE 1) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT5G44740

Predicted

Phenotypic Enhancement

FSW = 0.0779

Unknown

POLH (Y-FAMILT DNA POLYMERASE H) DNA-DIRECTED DNA POLYMERASE
AT1G55915

Predicted

Phenotypic Enhancement

FSW = 0.1396

Unknown

ZINC ION BINDING
AT5G26680

Predicted

synthetic growth defect

FSW = 0.2226

Unknown

ENDONUCLEASE PUTATIVE
AT5G13780

Predicted

synthetic growth defect

FSW = 0.1060

Unknown

GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE
AT1G55255Predicted

synthetic growth defect

FSW = 0.1304

Unknown

GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE
AT3G02820

Predicted

synthetic growth defect

Synthetic Lethality

FSW = 0.1743

Unknown

ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN
AT1G04730Predicted

synthetic growth defect

Synthetic Lethality

FSW = 0.1841

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT3G42660

Predicted

synthetic growth defect

Synthetic Lethality

FSW = 0.2440

Unknown

NUCLEOTIDE BINDING
AT2G44580

Predicted

synthetic growth defect

FSW = 0.2035

Unknown

PROTEIN BINDING / ZINC ION BINDING
AT1G24290

Predicted

synthetic growth defect

FSW = 0.1073

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT4G30870

Predicted

synthetic growth defect

FSW = 0.2121

Unknown

MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING
AT1G80410

Predicted

synthetic growth defect

FSW = 0.0948

Unknown

EMB2753 (EMBRYO DEFECTIVE 2753) BINDING
AT5G40490

Predicted

synthetic growth defect

FSW = 0.2013

Unknown

RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN
AT2G23420

Predicted

synthetic growth defect

FSW = 0.2743

Unknown

NAPRT2 (NICOTINATE PHOSPHORIBOSYLTRANSFERASE 2) NICOTINATE PHOSPHORIBOSYLTRANSFERASE
AT1G10930

Predicted

synthetic growth defect

Enriched domain pair

FSW = 0.3318

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT1G66740

Predicted

synthetic growth defect

FSW = 0.1364

Unknown

SGA2
AT4G25120Predicted

Synthetic Rescue

Synthetic Rescue

two hybrid

FSW = 0.3346

Unknown

ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING / HYDROLASE
AT1G67500

Predicted

Synthetic Rescue

FSW = 0.1604

Unknown

ATREV3 (ARABIDOPSIS THALIANA RECOVERY PROTEIN 3) DNA BINDING / DNA-DIRECTED DNA POLYMERASE
AT3G57870

Predicted

two hybrid

Enriched domain pair

Co-expression

FSW = 0.0362

Unknown

SCE1 (SUMO CONJUGATION ENZYME 1) SUMO LIGASE
AT1G08590

Predicted

Gene fusion method

FSW = 0.0703

Unknown

CLAVATA1 RECEPTOR KINASE (CLV1)
AT1G63300

Predicted

Gene fusion method

FSW = 0.0690

Unknown

UNKNOWN PROTEIN

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454