Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G41880 - ( POLA3 DNA primase )

75 Proteins interacs with AT5G41880
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT5G63400

Predicted

biochemical

FSW = 0.0065

Unknown

ADK1 (ADENYLATE KINASE 1) ATP BINDING / ADENYLATE KINASE/ NUCLEOBASE NUCLEOSIDE NUCLEOTIDE KINASE/ NUCLEOTIDE KINASE/ PHOSPHOTRANSFERASE PHOSPHATE GROUP AS ACCEPTOR
AT1G30470Predicted

Phenotypic Enhancement

FSW = 0.0217

Unknown

SIT4 PHOSPHATASE-ASSOCIATED FAMILY PROTEIN
AT3G22110

Predicted

Phenotypic Suppression

FSW = 0.0158

Unknown

PAC1 ENDOPEPTIDASE/ PEPTIDASE/ THREONINE-TYPE ENDOPEPTIDASE
AT3G02520

Predicted

Phenotypic Enhancement

FSW = 0.0880

Unknown

GRF7 (GENERAL REGULATORY FACTOR 7) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING
AT1G48850

Predicted

Affinity Capture-Western

FSW = 0.0333

Unknown

EMB1144 (EMBRYO DEFECTIVE 1144) CHORISMATE SYNTHASE
AT5G59690Predicted

Phenotypic Suppression

FSW = 0.0882

Unknown

HISTONE H4
AT3G13560

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0031

Unknown

GLYCOSYL HYDROLASE FAMILY 17 PROTEIN
AT1G11890

Predicted

Phenotypic Enhancement

FSW = 0.0747

Unknown

SEC22 TRANSPORTER
AT4G26110

Predicted

Affinity Capture-MS

FSW = 0.0489

Unknown

NAP11 (NUCLEOSOME ASSEMBLY PROTEIN11) DNA BINDING
AT3G18524

Predicted

Phenotypic Enhancement

FSW = 0.0596

Unknown

MSH2 (MUTS HOMOLOG 2) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT2G19480

Predicted

Affinity Capture-MS

FSW = 0.0257

Unknown

NAP12 (NUCLEOSOME ASSEMBLY PROTEIN 12) DNA BINDING
AT2G44680

Predicted

Phenotypic Suppression

FSW = 0.0818

Unknown

CKB4 (CASEIN KINASE II BETA SUBUNIT 4) PROTEIN SERINE/THREONINE KINASE
AT4G26720

Predicted

Phenotypic Enhancement

FSW = 0.0455

Unknown

PPX1 (PROTEIN PHOSPHATASE X 1) PROTEIN SERINE/THREONINE PHOSPHATASE
AT2G24490

Predicted

Colocalization

Co-expression

FSW = 0.1969

Unknown

RPA2 (REPLICON PROTEIN A2) PROTEIN BINDING
AT3G12810

Predicted

Phenotypic Enhancement

FSW = 0.1299

Unknown

PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT5G37720

Predicted

Affinity Capture-MS

FSW = 0.0378

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT4G13980

Predicted

biochemical

FSW = 0.0104

Unknown

AT-HSFA5 DNA BINDING / TRANSCRIPTION FACTOR
AT5G35910

Predicted

Phenotypic Enhancement

FSW = 0.0586

Unknown

3-5 EXONUCLEASE DOMAIN-CONTAINING PROTEIN / HELICASE AND RNASE D C-TERMINAL DOMAIN-CONTAINING PROTEIN / HRDC DOMAIN-CONTAINING PROTEIN
AT1G19120

Predicted

Phenotypic Enhancement

FSW = 0.1013

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE
AT1G02740

Predicted

Phenotypic Suppression

FSW = 0.0517

Unknown

CHROMATIN BINDING
AT2G13370

Predicted

Phenotypic Enhancement

FSW = 0.0853

Unknown

CHR5 (CHROMATIN REMODELING 5) ATP BINDING / DNA BINDING / CHROMATIN BINDING / HELICASE/ NUCLEIC ACID BINDING
AT2G36740

Predicted

Phenotypic Enhancement

FSW = 0.1295

Unknown

SWC2 DNA BINDING / TRANSCRIPTION FACTOR
AT3G19210

Predicted

Phenotypic Enhancement

FSW = 0.1140

Unknown

ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT5G08630

Predicted

Phenotypic Suppression

FSW = 0.0781

Unknown

DDT DOMAIN-CONTAINING PROTEIN
AT1G65470

Predicted

Phenotypic Suppression

FSW = 0.1355

Unknown

FAS1 (FASCIATA 1) HISTONE BINDING
AT5G18620

Predicted

Phenotypic Suppression

FSW = 0.0508

Unknown

CHR17 (CHROMATIN REMODELING FACTOR17) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ HELICASE/ HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING / NUCLEOSOME BINDING
AT1G67630

Predicted

in vitro

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

interaction prediction

Co-expression

FSW = 0.0787

Unknown

POLA2 (DNA POLYMERASE ALPHA 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE
AT5G57450

Predicted

Phenotypic Enhancement

FSW = 0.1124

Unknown

XRCC3 ATP BINDING / DAMAGED DNA BINDING / PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
AT5G66130

Predicted

Phenotypic Enhancement

FSW = 0.1421

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT5G40820

Predicted

Synthetic Lethality

FSW = 0.1134

Unknown

ATRAD3 BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR / PROTEIN SERINE/THREONINE KINASE
AT5G19910

Predicted

Phenotypic Enhancement

FSW = 0.1009

Unknown

SOH1 FAMILY PROTEIN
AT5G20850

Predicted

Phenotypic Enhancement

FSW = 0.0972

Unknown

ATRAD51 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING / SEQUENCE-SPECIFIC DNA BINDING
AT3G57490

Predicted

two hybrid

Co-expression

FSW = 0.0108

Unknown

40S RIBOSOMAL PROTEIN S2 (RPS2D)
AT4G34110

Predicted

two hybrid

FSW = 0.0127

Unknown

PAB2 (POLY(A) BINDING 2) RNA BINDING / TRANSLATION INITIATION FACTOR
AT3G12280

Predicted

Phenotypic Enhancement

FSW = 0.0081

Unknown

RBR1 (RETINOBLASTOMA-RELATED 1) TRANSCRIPTION FACTOR BINDING
AT1G34370

Predicted

two hybrid

FSW = 0.0138

Unknown

STOP1 (SENSITIVE TO PROTON RHIZOTOXICITY 1) NUCLEIC ACID BINDING / TRANSCRIPTION FACTOR/ ZINC ION BINDING
AT1G08260

Predicted

Reconstituted Complex

Co-purification

Co-expression

FSW = 0.0285

Unknown

TIL1 (TILTED 1) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING
AT1G09020

Predicted

Phenotypic Suppression

FSW = 0.0337

Unknown

SNF4 (HOMOLOG OF YEAST SUCROSE NONFERMENTING 4) PROTEIN KINASE ACTIVATOR
AT1G51310

Predicted

Phenotypic Suppression

FSW = 0.0866

Unknown

TRNA (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE
AT1G51710

Predicted

Phenotypic Enhancement

FSW = 0.0511

Unknown

UBP6 (UBIQUITIN-SPECIFIC PROTEASE 6) CALMODULIN BINDING / UBIQUITIN-SPECIFIC PROTEASE
AT1G67320

Predicted

Synthetic Lethality

Co-purification

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

Co-expression

FSW = 0.2234

Unknown

DNA PRIMASE LARGE SUBUNIT FAMILY
AT2G28390

Predicted

Phenotypic Enhancement

FSW = 0.0138

Unknown

SAND FAMILY PROTEIN
AT3G04710

Predicted

Phenotypic Suppression

FSW = 0.0381

Unknown

ANKYRIN REPEAT FAMILY PROTEIN
AT3G24010

Predicted

Affinity Capture-MS

FSW = 0.0062

Unknown

ING1 (INHIBITOR OF GROWTH 1) DNA BINDING / METHYLATED HISTONE RESIDUE BINDING
AT4G04210

Predicted

Phenotypic Suppression

FSW = 0.1013

Unknown

PUX4 PROTEIN BINDING
AT4G30870

Predicted

Phenotypic Enhancement

FSW = 0.1172

Unknown

MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING
AT1G10930

Predicted

Phenotypic Enhancement

FSW = 0.1094

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT1G15780

Predicted

Phenotypic Suppression

FSW = 0.0508

Unknown

UNKNOWN PROTEIN
AT1G52740

Predicted

Phenotypic Enhancement

FSW = 0.0927

Unknown

HTA9 (HISTONE H2A PROTEIN 9) DNA BINDING
AT1G54320

Predicted

Phenotypic Suppression

FSW = 0.0285

Unknown

LEM3 (LIGAND-EFFECT MODULATOR 3) FAMILY PROTEIN / CDC50 FAMILY PROTEIN
AT1G59890

Predicted

Phenotypic Suppression

FSW = 0.2313

Unknown

SNL5 (SIN3-LIKE 5)
AT1G79890

Predicted

Phenotypic Enhancement

FSW = 0.0268

Unknown

HELICASE-RELATED
AT2G23070

Predicted

Phenotypic Suppression

FSW = 0.0263

Unknown

CASEIN KINASE II ALPHA CHAIN PUTATIVE
AT2G44150

Predicted

Phenotypic Suppression

FSW = 0.0964

Unknown

ASHH3 (HISTONE-LYSINE N-METHYLTRANSFERASE ASHH3) HISTONE-LYSINE N-METHYLTRANSFERASE
AT3G02820

Predicted

Phenotypic Enhancement

FSW = 0.0838

Unknown

ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN
AT3G18630

Predicted

Phenotypic Suppression

FSW = 0.0475

Unknown

URACIL DNA GLYCOSYLASE FAMILY PROTEIN
AT3G18860

Predicted

Phenotypic Enhancement

FSW = 0.1196

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G58560

Predicted

Phenotypic Enhancement

FSW = 0.0889

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT3G62040

Predicted

two hybrid

FSW = 0.0410

Unknown

CATALYTIC/ HYDROLASE
AT4G25120Predicted

Phenotypic Enhancement

FSW = 0.1229

Unknown

ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING / HYDROLASE
AT4G33100

Predicted

Phenotypic Suppression

FSW = 0.0494

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY FAMILY 35/APOPTOSIS (INTERPROIPR007918) HAS 160 BLAST HITS TO 160 PROTEINS IN 70 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 95 FUNGI - 46 PLANTS - 13 VIRUSES - 0 OTHER EUKARYOTES - 6 (SOURCE NCBI BLINK)
AT5G02310

Predicted

Phenotypic Suppression

FSW = 0.0169

Unknown

PRT6 (PROTEOLYSIS 6) UBIQUITIN-PROTEIN LIGASE
AT5G10960

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.1389

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT5G42000

Predicted

Phenotypic Suppression

FSW = 0.0808

Unknown

ORMDL FAMILY PROTEIN
AT5G61150

Predicted

Phenotypic Suppression

FSW = 0.1219

Unknown

VIP4 (VERNALIZATION INDEPENDENCE 4) PROTEIN BINDING
AT5G63920

Predicted

Phenotypic Enhancement

FSW = 0.0856

Unknown

DNA TOPOISOMERASE III ALPHA PUTATIVE
AT5G67100

Predicted

Co-purification

Colocalization

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

interaction prediction

Co-expression

FSW = 0.1319

Unknown

ICU2 (INCURVATA2) DNA-DIRECTED DNA POLYMERASE
AT5G61770

Predicted

Phenotypic Suppression

FSW = 0.0147

Unknown

PPAN (PETER PAN-LIKE PROTEIN)
AT5G66620

Predicted

Affinity Capture-Western

FSW = 0.0198

Unknown

DAR6 (DA1-RELATED PROTEIN 6) ZINC ION BINDING
AT5G67320

Predicted

Phenotypic Suppression

FSW = 0.0687

Unknown

HOS15 (HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 15)
AT5G02530

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0198

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT1G15920

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0942

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT1G49760

Predicted

two hybrid

Co-expression

FSW = 0.0246

Unknown

PAB8 (POLY(A) BINDING PROTEIN 8) RNA BINDING / TRANSLATION INITIATION FACTOR
AT2G32070

Predicted

interaction prediction

FSW = 0.1051

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT2G27120

Predicted

interaction prediction

FSW = 0.0787

Unknown

TIL2 (TILTED 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454