Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G45970 - ( ARAC2 (ARABIDOPSIS RAC-LIKE 2) GTP binding )

65 Proteins interacs with AT5G45970
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT2G38440

Experimental

FSW = 0.0741

Class A:

plasma membrane

SCAR2 (SCAR HOMOLOG 2)
AT4G38430

Experimental

biochemical

FSW = 0.0981

Class A:

plasma membrane

ROPGEF1 RHO GUANYL-NUCLEOTIDE EXCHANGE FACTOR/ PROTEIN BINDING
AT5G15090

Predicted

Affinity Capture-Western

Affinity Capture-MS

FSW = 0.0070

Class C:

plasma membrane

VDAC3 (VOLTAGE DEPENDENT ANION CHANNEL 3) VOLTAGE-GATED ANION CHANNEL
AT4G14960

Predicted

Affinity Capture-MS

in vivo

FSW = 0.0024

Class C:

plasma membrane

TUA6 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT5G10450

Predicted

Affinity Capture-MS

FSW = 0.0442

Class C:

plasma membrane

GRF6 (G-BOX REGULATING FACTOR 6) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING
AT5G62880

Predicted

Gene neighbors method

Phylogenetic profile method

Co-expression

FSW = 0.0961

Class C:

plasma membrane

ARAC10 GTP BINDING
AT1G71860

Predicted

Phenotypic Enhancement

FSW = 0.0449

Class C:

plasma membrane

PTP1 (PROTEIN TYROSINE PHOSPHATASE 1) PROTEIN TYROSINE PHOSPHATASE
AT1G75840

Predicted

Phenotypic Enhancement

Phylogenetic profile method

Co-expression

FSW = 0.1420

Class C:

plasma membrane

ARAC5 (RAC-LIKE GTP BINDING PROTEIN 5) GTP BINDING / GTPASE
AT3G47370

Predicted

Affinity Capture-MS

FSW = 0.0166

Class C:

plasma membrane

40S RIBOSOMAL PROTEIN S20 (RPS20B)
AT1G12310

Predicted

Phenotypic Suppression

Phenotypic Enhancement

FSW = 0.0497

Class C:

plasma membrane

CALMODULIN PUTATIVE
AT4G28950

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.0935

Class C:

plasma membrane

ROP9 (RHO-RELATED PROTEIN FROM PLANTS 9) GTP BINDING
AT1G20090

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.1111

Class C:

plasma membrane

ROP2 (RHO-RELATED PROTEIN FROM PLANTS 2) GTP BINDING
AT1G50360

Predicted

Phenotypic Suppression

FSW = 0.0373

Class C:

plasma membrane

VIIIA MOTOR
AT2G44690

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.1641

Class C:

plasma membrane

ARAC9 GTP BINDING
AT4G35020

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.0972

Class C:

plasma membrane

ARAC3 (ARABIDOPSIS RAC-LIKE 3) GTP BINDING / GTPASE
AT4G35950

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.1893

Class C:

plasma membrane

ARAC6 (ARABIDOPSIS RAC-LIKE 6) GTP BINDING
AT3G48040

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.2970

Class C:

plasma membrane

ROP10 (RHO-RELATED PROTEIN FROM PLANTS 10) GTP BINDING / GTPASE
AT4G02450

Predicted

in vivo

FSW = 0.0153

Class C:

plasma membrane

GLYCINE-RICH PROTEIN
AT5G54280

Predicted

Phenotypic Suppression

FSW = 0.1167

Class C:

plasma membrane

ATM2 (ARABIDOPSIS THALIANA MYOSIN 2) MOTOR
AT3G05630

Predicted

in vivo

in vitro

in vivo

in vitro

biochemical

Reconstituted Complex

FSW = 0.0381

Unknown

PLDP2 PHOSPHOLIPASE D
AT2G39290

Predicted

Affinity Capture-MS

FSW = 0.0100

Unknown

PGP1 (PHOSPHATIDYLGLYCEROLPHOSPHATE SYNTHASE 1) CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE/ CDP-DIACYLGLYCEROL-GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE
AT5G19390

Predicted

Affinity Capture-MS

in vivo

Reconstituted Complex

FSW = 0.0471

Unknown

PLECKSTRIN HOMOLOGY (PH) DOMAIN-CONTAINING PROTEIN / RHOGAP DOMAIN-CONTAINING PROTEIN
AT5G25400

Predicted

Affinity Capture-MS

FSW = 0.0035

Unknown

PHOSPHATE TRANSLOCATOR-RELATED
AT5G60980

Predicted

Phenotypic Enhancement

FSW = 0.0041

Unknown

NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN / RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN
AT4G34390

Predicted

Phenotypic Enhancement

FSW = 0.0571

Unknown

XLG2 (EXTRA-LARGE GTP-BINDING PROTEIN 2) GUANYL NUCLEOTIDE BINDING / SIGNAL TRANSDUCER
AT1G69220

Predicted

Reconstituted Complex

in vitro

in vitro

in vitro

in vivo

two hybrid

Reconstituted Complex

FSW = 0.0721

Unknown

SIK1 ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT5G23320

Predicted

in vitro

in vivo

FSW = 0.0235

Unknown

ATSTE14A (ARABIDOPSIS HOMOLOG OF YEAST STE14 A) CARBOXYL-O-METHYLTRANSFERASE/ PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE
AT3G51300

Predicted

Phenotypic Enhancement

Phylogenetic profile method

Co-expression

FSW = 0.1400

Unknown

ROP1 (RHO-RELATED PROTEIN FROM PLANTS 1) GTP BINDING / GTPASE ACTIVATING PROTEIN BINDING / GTPASE/ PROTEIN BINDING
AT5G56600

Predicted

Phenotypic Suppression

FSW = 0.0671

Unknown

PRF3 (PROFILIN 3) ACTIN BINDING
AT2G17800

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.2072

Unknown

ARAC1 GTP BINDING
AT4G02570

Predicted

two hybrid

Affinity Capture-MS

FSW = 0.0055

Unknown

ATCUL1 (ARABIDOPSIS THALIANA CULLIN 1) PROTEIN BINDING
AT5G03730

Predicted

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.1122

Unknown

CTR1 (CONSTITUTIVE TRIPLE RESPONSE 1) KINASE/ PROTEIN BINDING / PROTEIN SERINE/THREONINE KINASE/ PROTEIN SERINE/THREONINE/TYROSINE KINASE
AT2G19770

Predicted

Phenotypic Suppression

FSW = 0.0315

Unknown

PRF5 (PROFILIN5) ACTIN BINDING / ACTIN MONOMER BINDING
AT2G29900

Predicted

Phenotypic Enhancement

FSW = 0.0752

Unknown

PRESENILIN FAMILY PROTEIN
AT3G07880

Predicted

Affinity Capture-MS

Affinity Capture-MS

in vitro

two hybrid

in vivo

in vivo

in vivo

in vitro

two hybrid

in vivo

in vitro

Co-purification

FSW = 0.0961

Unknown

RHO GDP-DISSOCIATION INHIBITOR FAMILY PROTEIN
AT2G35110

Predicted

Phenotypic Suppression

Phenotypic Suppression

Phenotypic Enhancement

in vivo

in vitro

FSW = 0.1176

Unknown

GRL (GNARLED) TRANSCRIPTION ACTIVATOR
AT4G36080Predicted

Phenotypic Enhancement

FSW = 0.0247

Unknown

FAT DOMAIN-CONTAINING PROTEIN / PHOSPHATIDYLINOSITOL 3- AND 4-KINASE FAMILY PROTEIN
AT5G09740

Predicted

Phenotypic Enhancement

FSW = 0.0145

Unknown

HAM2 (HISTONE ACETYLTRANSFERASE OF THE MYST FAMILY 2) H3/H4 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE/ NUCLEIC ACID BINDING / ZINC ION BINDING
AT5G23420

Predicted

Phenotypic Enhancement

FSW = 0.0522

Unknown

HMGB6 TRANSCRIPTION FACTOR
AT3G12280

Predicted

Phenotypic Enhancement

FSW = 0.0178

Unknown

RBR1 (RETINOBLASTOMA-RELATED 1) TRANSCRIPTION FACTOR BINDING
AT4G17760

Predicted

two hybrid

FSW = 0.0305

Unknown

DAMAGED DNA BINDING / EXODEOXYRIBONUCLEASE III
AT2G31320

Predicted

Phenotypic Suppression

FSW = 0.0196

Unknown

PARP2 (POLY(ADP-RIBOSE) POLYMERASE 2) DNA BINDING / NAD OR NADH BINDING / NAD+ ADP-RIBOSYLTRANSFERASE/ ZINC ION BINDING
AT4G11330

Predicted

Phenotypic Suppression

Phenotypic Suppression

Co-purification

FSW = 0.0501

Unknown

ATMPK5 (MAP KINASE 5) MAP KINASE/ KINASE
AT5G06150

Predicted

Phenotypic Suppression

FSW = 0.0346

Unknown

CYC1BAT CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT1G54380

Predicted

two hybrid

FSW = 0.0181

Unknown

SPLICEOSOME PROTEIN-RELATED
AT5G56580

Predicted

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.1144

Unknown

MKK6 (MAP KINASE KINASE 6) MAP KINASE KINASE/ KINASE
AT5G57610

Predicted

in vitro

Phenotypic Suppression

in vitro

FSW = 0.0909

Unknown

PROTEIN KINASE FAMILY PROTEIN
AT2G27600

Predicted

in vivo

in vitro

two hybrid

FSW = 0.0052

Unknown

SKD1 (SUPPRESSOR OF K+ TRANSPORT GROWTH DEFECT1) ATP BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT3G60260

Predicted

Reconstituted Complex

Affinity Capture-Western

FSW = 0.0294

Unknown

PHAGOCYTOSIS AND CELL MOTILITY PROTEIN ELMO1-RELATED
AT4G35750

Predicted

in vitro

two hybrid

Affinity Capture-MS

in vitro

FSW = 0.0217

Unknown

RHO-GTPASE-ACTIVATING PROTEIN-RELATED
AT5G07110

Predicted

Affinity Capture-MS

in vivo

two hybrid

FSW = 0.0138

Unknown

PRA1B6 (PRENYLATED RAB ACCEPTOR 1B6)
AT5G18410

Predicted

Affinity Capture-MS

in vivo

in vitro

FSW = 0.1174

Unknown

PIR121 TRANSCRIPTION ACTIVATOR
AT4G31480

Predicted

in vivo

FSW = 0.0295

Unknown

COATOMER BETA SUBUNIT PUTATIVE / BETA-COAT PROTEIN PUTATIVE / BETA-COP PUTATIVE
AT4G34450

Predicted

in vivo

FSW = 0.0282

Unknown

COATOMER GAMMA-2 SUBUNIT PUTATIVE / GAMMA-2 COAT PROTEIN PUTATIVE / GAMMA-2 COP PUTATIVE
AT4G34540

Predicted

Affinity Capture-MS

far western blotting

FSW = 0.0333

Unknown

ISOFLAVONE REDUCTASE FAMILY PROTEIN
AT5G22400

Predicted

biochemical

FSW = 0.1504

Unknown

RAC GTPASE ACTIVATING PROTEIN PUTATIVE
AT5G52350

Predicted

Affinity Capture-Western

two hybrid

FSW = 0.0159

Unknown

ATEXO70A3 (EXOCYST SUBUNIT EXO70 FAMILY PROTEIN A3) PROTEIN BINDING
AT5G58690

Predicted

in vivo

in vitro

FSW = 0.1137

Unknown

PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN
AT5G63770

Predicted

in vivo

in vitro

FSW = 0.0536

Unknown

ATDGK2 (DIACYLGLYCEROL KINASE 2) DIACYLGLYCEROL KINASE
AT5G61530

Predicted

two hybrid

FSW = 0.0102

Unknown

SMALL G PROTEIN FAMILY PROTEIN / RHOGAP FAMILY PROTEIN
AT1G05000

Predicted

Affinity Capture-MS

FSW = 0.0261

Unknown

TYROSINE SPECIFIC PROTEIN PHOSPHATASE FAMILY PROTEIN
AT1G60730

Predicted

Protein-RNA

FSW = 0.0090

Unknown

ALDO/KETO REDUCTASE FAMILY PROTEIN
AT2G44820

Predicted

Protein-RNA

FSW = 0.0163

Unknown

UNKNOWN PROTEIN
AT4G29140

Predicted

Affinity Capture-MS

FSW = 0.0163

Unknown

MATE EFFLUX PROTEIN-RELATED
AT4G31170

Predicted

Phenotypic Suppression

FSW = 0.0914

Unknown

PROTEIN KINASE FAMILY PROTEIN

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

Learn more

How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454