Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G55300 - ( TOP1ALPHA (DNA TOPOISOMERASE I ALPHA) DNA topoisomerase type I )
38 Proteins interacs with AT5G55300Locus | Method | FSW | Cellular Compartment Classification (C3) | Description |
---|---|---|---|---|
AT1G78300 | Experimental | FSW = 0.0027
| Unknown | GRF2 (GENERAL REGULATORY FACTOR 2) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING |
AT2G05710 | PredictedAffinity Capture-MS | FSW = 0.0357
| Unknown | ACONITATE HYDRATASE CYTOPLASMIC PUTATIVE / CITRATE HYDRO-LYASE/ACONITASE PUTATIVE |
AT3G52140 | PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0195
| Unknown | TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN |
AT1G07790 | PredictedAffinity Capture-MSCo-expression | FSW = 0.0361
| Unknown | HTB1 DNA BINDING |
AT4G26970 | Predictedinteraction prediction | FSW = 0.0090
| Unknown | ACONITATE HYDRATASE/ COPPER ION BINDING |
AT5G17770 | PredictedAffinity Capture-MS | FSW = 0.0392
| Unknown | ATCBR (ARABIDOPSIS THALIANA NADHCYTOCHROME B5 REDUCTASE 1) CYTOCHROME-B5 REDUCTASE |
AT1G05570 | Predictedinteraction prediction | FSW = 0.0245
| Unknown | CALS1 (CALLOSE SYNTHASE 1) 13-BETA-GLUCAN SYNTHASE/ TRANSFERASE TRANSFERRING GLYCOSYL GROUPS |
AT2G44860 | PredictedAffinity Capture-MS | FSW = 0.0119
| Unknown | 60S RIBOSOMAL PROTEIN L24 PUTATIVE |
AT4G10670 | PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0525
| Unknown | GTC2 |
AT5G09860 | Predictedsynthetic growth defectsynthetic growth defectsynthetic growth defectSynthetic Lethalityinteraction prediction | FSW = 0.0947
| Unknown | NUCLEAR MATRIX PROTEIN-RELATED |
AT4G10710 | Predictedinteraction predictionCo-expression | FSW = 0.0295
| Unknown | SPT16 (GLOBAL TRANSCRIPTION FACTOR C) |
AT1G48920 | PredictedAffinity Capture-Western | FSW = 0.0252
| Unknown | ATNUC-L1 NUCLEIC ACID BINDING / NUCLEOTIDE BINDING |
AT4G38130 | PredictedAffinity Capture-MSAffinity Capture-MSinteraction prediction | FSW = 0.0556
| Unknown | HD1 (HISTONE DEACETYLASE 1) BASAL TRANSCRIPTION REPRESSOR/ HISTONE DEACETYLASE/ PROTEIN BINDING |
AT5G60410 | Predictedbiochemical | FSW = 0.1231
| Unknown | SIZ1 DNA BINDING / SUMO LIGASE |
AT5G41150 | PredictedPhenotypic Enhancement | FSW = 0.0938
| Unknown | UVH1 (ULTRAVIOLET HYPERSENSITIVE 1) SINGLE-STRANDED DNA SPECIFIC ENDODEOXYRIBONUCLEASE |
AT2G31970 | Predictedinteraction predictionSynthetic LethalityCo-expression | FSW = 0.1055
| Unknown | RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING |
AT3G23890 | PredictedSynthetic Lethalitysynthetic growth defectsynthetic growth defectPhenotypic EnhancementPhenotypic EnhancementPhenotypic EnhancementPhenotypic EnhancementSynthetic Lethalitysynthetic growth defectCo-expression | FSW = 0.2097
| Unknown | TOPII (TOPOISOMERASE II) ATP BINDING / DNA BINDING / DNA TOPOISOMERASE (ATP-HYDROLYZING)/ DNA TOPOISOMERASE/ DNA-DEPENDENT ATPASE |
AT3G28730 | PredictedAffinity Capture-MSCo-expression | FSW = 0.0711
| Unknown | ATHMG (ARABIDOPSIS THALIANA HIGH MOBILITY GROUP) TRANSCRIPTION FACTOR |
AT4G26840 | PredictedAffinity Capture-MS | FSW = 0.0210
| Unknown | SUMO1 (SMALL UBIQUITIN-LIKE MODIFIER 1) PROTEIN BINDING / PROTEIN TAG |
AT5G54260 | PredictedSynthetic Lethalityinteraction prediction | FSW = 0.0904
| Unknown | MRE11 (MEIOTIC RECOMBINATION 11) ENDONUCLEASE/ EXONUCLEASE/ HYDROLASE/ MANGANESE ION BINDING / PROTEIN SERINE/THREONINE PHOSPHATASE |
AT5G22480 | Predictedtwo hybridtwo hybrid | FSW = 0.0195
| Unknown | ZINC FINGER (ZPR1-TYPE) FAMILY PROTEIN |
AT4G30870 | PredictedSynthetic Rescue | FSW = 0.0767
| Unknown | MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING |
AT3G20630 | PredictedAffinity Capture-MS | FSW = 0.0317
| Unknown | UBP14 (UBIQUITIN-SPECIFIC PROTEASE 14) UBIQUITIN-SPECIFIC PROTEASE |
AT3G60240 | PredictedAffinity Capture-MS | FSW = 0.0079
| Unknown | EIF4G (EUKARYOTIC TRANSLATION INITIATION FACTOR 4G) TRANSLATION INITIATION FACTOR |
AT1G54390 | PredictedPhenotypic Enhancement | FSW = 0.0464
| Unknown | PHD FINGER PROTEIN-RELATED |
AT5G53770 | PredictedSynthetic LethalityPhenotypic EnhancementSynthetic Lethalityinteraction prediction | FSW = 0.0562
| Unknown | NUCLEOTIDYLTRANSFERASE FAMILY PROTEIN |
AT1G10930 | Predictedinteraction predictionSynthetic LethalitySynthetic LethalitySynthetic Lethalitysynthetic growth defectsynthetic growth defectsynthetic growth defectSynthetic Rescue | FSW = 0.0941
| Unknown | RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING |
AT3G13224 | Predictedsynthetic growth defect | FSW = 0.0373
| Unknown | RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN |
AT1G66740 | PredictedSynthetic Lethalityinteraction prediction | FSW = 0.0441
| Unknown | SGA2 |
AT5G63920 | PredictedSynthetic Lethalityinteraction predictionCo-expression | FSW = 0.1711
| Unknown | DNA TOPOISOMERASE III ALPHA PUTATIVE |
AT1G29630 | PredictedSynthetic Lethalityinteraction prediction | FSW = 0.0582
| Unknown | NUCLEASE |
AT3G25100 | PredictedSynthetic LethalitySynthetic LethalityCo-expression | FSW = 0.0495
| Unknown | CDC45 (CELL DIVISION CYCLE 45) |
AT3G57870 | PredictedSynthetic Lethality | FSW = 0.0295
| Unknown | SCE1 (SUMO CONJUGATION ENZYME 1) SUMO LIGASE |
AT2G27600 | PredictedSynthetic Rescue | FSW = 0.0186
| Unknown | SKD1 (SUPPRESSOR OF K+ TRANSPORT GROWTH DEFECT1) ATP BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING |
AT1G49520 | Predictedtwo hybridtwo hybrid | FSW = 0.0261
| Unknown | SWIB COMPLEX BAF60B DOMAIN-CONTAINING PROTEIN |
AT5G15770 | Predictedinteraction prediction | FSW = 0.0232
| Unknown | ATGNA1 (ARABIDOPSIS THALIANA GLUCOSE-6-PHOSPHATE ACETYLTRANSFERASE 1) N-ACETYLTRANSFERASE/ GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE |
AT3G53650 | Predictedinteraction predictionCo-expression | FSW = 0.0199
| Unknown | HISTONE H2B PUTATIVE |
AT5G55310 | PredictedEnriched domain pairPhylogenetic profile methodCo-expression | FSW = 0.4246
| Unknown | TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA TOPOISOMERASE TYPE I |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454