Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G55310 - ( TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA topoisomerase type I )
66 Proteins interacs with AT5G55310Locus | Method | FSW | Cellular Compartment Classification (C3) | Description |
---|---|---|---|---|
AT3G52140 | PredictedAffinity Capture-MS | FSW = 0.0117
| Unknown | TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN |
AT5G63110 | PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0800
| Unknown | HDA6 (HISTONE DEACETYLASE 6) HISTONE DEACETYLASE |
AT4G35830 | PredictedAffinity Capture-MS | FSW = 0.0171
| Unknown | ACONITATE HYDRATASE CYTOPLASMIC / CITRATE HYDRO-LYASE / ACONITASE (ACO) |
AT5G17770 | PredictedAffinity Capture-MS | FSW = 0.0237
| Unknown | ATCBR (ARABIDOPSIS THALIANA NADHCYTOCHROME B5 REDUCTASE 1) CYTOCHROME-B5 REDUCTASE |
AT1G11890 | PredictedPhenotypic Suppression | FSW = 0.0742
| Unknown | SEC22 TRANSPORTER |
AT2G44860 | PredictedAffinity Capture-MS | FSW = 0.0188
| Unknown | 60S RIBOSOMAL PROTEIN L24 PUTATIVE |
AT5G35910 | PredictedPhenotypic Suppression | FSW = 0.1630
| Unknown | 3-5 EXONUCLEASE DOMAIN-CONTAINING PROTEIN / HELICASE AND RNASE D C-TERMINAL DOMAIN-CONTAINING PROTEIN / HRDC DOMAIN-CONTAINING PROTEIN |
AT2G43810 | PredictedPhenotypic Enhancement | FSW = 0.0882
| Unknown | SMALL NUCLEAR RIBONUCLEOPROTEIN F PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE / SM PROTEIN F PUTATIVE |
AT1G19120 | PredictedPhenotypic Enhancement | FSW = 0.1218
| Unknown | SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE |
AT3G13940 | PredictedPhenotypic Enhancementinterologs mappingSynthetic Lethality | FSW = 0.0675
| Unknown | DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
AT4G10710 | PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0994
| Unknown | SPT16 (GLOBAL TRANSCRIPTION FACTOR C) |
AT1G48920 | PredictedAffinity Capture-Western | FSW = 0.0151
| Unknown | ATNUC-L1 NUCLEIC ACID BINDING / NUCLEOTIDE BINDING |
AT1G02840 | Predictedin vitroin vivo | FSW = 0.0061
| Unknown | SR1 RNA BINDING / NUCLEIC ACID BINDING / NUCLEOTIDE BINDING |
AT1G05055 | PredictedPhenotypic Enhancement | FSW = 0.0481
| Unknown | GTF2H2 (GENERAL TRANSCRIPTION FACTOR IIH 2) GENERAL RNA POLYMERASE II TRANSCRIPTION FACTOR |
AT1G07370 | PredictedPhenotypic Suppression | FSW = 0.1567
| Unknown | PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING |
AT4G14300 | Predictedsynthetic growth defect | FSW = 0.0224
| Unknown | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / HNRNP PUTATIVE |
AT3G18610 | Predictedin vivoin vivoin vitroin vitroin vitroin vivo | FSW = 0.0178
| Unknown | ATRANGAP1 (RAN GTPASE-ACTIVATING PROTEIN 1) NUCLEIC ACID BINDING / NUCLEOTIDE BINDING |
AT2G06210 | PredictedPhenotypic Enhancement | FSW = 0.0785
| Unknown | ELF8 (EARLY FLOWERING 8) BINDING |
AT5G41150 | PredictedPhenotypic Enhancement | FSW = 0.0819
| Unknown | UVH1 (ULTRAVIOLET HYPERSENSITIVE 1) SINGLE-STRANDED DNA SPECIFIC ENDODEOXYRIBONUCLEASE |
AT2G31970 | PredictedSynthetic Lethality | FSW = 0.1222
| Unknown | RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING |
AT3G23890 | PredictedPhenotypic Enhancementsynthetic growth defectPhenotypic EnhancementSynthetic Lethalitysynthetic growth defect | FSW = 0.0880
| Unknown | TOPII (TOPOISOMERASE II) ATP BINDING / DNA BINDING / DNA TOPOISOMERASE (ATP-HYDROLYZING)/ DNA TOPOISOMERASE/ DNA-DEPENDENT ATPASE |
AT3G28730 | PredictedAffinity Capture-MS | FSW = 0.0854
| Unknown | ATHMG (ARABIDOPSIS THALIANA HIGH MOBILITY GROUP) TRANSCRIPTION FACTOR |
AT4G26840 | PredictedAffinity Capture-MS | FSW = 0.0365
| Unknown | SUMO1 (SMALL UBIQUITIN-LIKE MODIFIER 1) PROTEIN BINDING / PROTEIN TAG |
AT5G54260 | PredictedSynthetic LethalityPhenotypic Enhancement | FSW = 0.1383
| Unknown | MRE11 (MEIOTIC RECOMBINATION 11) ENDONUCLEASE/ EXONUCLEASE/ HYDROLASE/ MANGANESE ION BINDING / PROTEIN SERINE/THREONINE PHOSPHATASE |
AT5G37340 | Predictedtwo hybrid | FSW = 0.0257
| Unknown | ZINC FINGER (ZPR1-TYPE) FAMILY PROTEIN |
AT1G09020 | PredictedPhenotypic Enhancement | FSW = 0.0135
| Unknown | SNF4 (HOMOLOG OF YEAST SUCROSE NONFERMENTING 4) PROTEIN KINASE ACTIVATOR |
AT1G10930 | Predictedsynthetic growth defectsynthetic growth defectSynthetic Lethalitysynthetic growth defectSynthetic LethalitySynthetic Lethalitysynthetic growth defectPhenotypic Enhancement | FSW = 0.1101
| Unknown | RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING |
AT1G18090 | PredictedSynthetic Lethality | FSW = 0.1320
| Unknown | EXONUCLEASE PUTATIVE |
AT1G24706 | PredictedPhenotypic Enhancement | FSW = 0.0046
| Unknown | UNKNOWN PROTEIN |
AT1G49520 | Predictedtwo hybridtwo hybrid | FSW = 0.0105
| Unknown | SWIB COMPLEX BAF60B DOMAIN-CONTAINING PROTEIN |
AT1G66740 | PredictedSynthetic Lethality | FSW = 0.0943
| Unknown | SGA2 |
AT1G79730 | PredictedPhenotypic Enhancement | FSW = 0.0618
| Unknown | ELF7 (EARLY FLOWERING 7) |
AT2G27600 | PredictedSynthetic Rescue | FSW = 0.0192
| Unknown | SKD1 (SUPPRESSOR OF K+ TRANSPORT GROWTH DEFECT1) ATP BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING |
AT2G34770 | PredictedPhenotypic Enhancement | FSW = 0.0153
| Unknown | FAH1 (FATTY ACID HYDROXYLASE 1) CATALYTIC/ FATTY ACID ALPHA-HYDROXYLASE |
AT3G10070 | PredictedPhenotypic Suppression | FSW = 0.0210
| Unknown | TAF12 (TBP-ASSOCIATED FACTOR 12) DNA BINDING / TRANSCRIPTION INITIATION FACTOR |
AT3G18520 | PredictedPhenotypic Suppression | FSW = 0.0699
| Unknown | HDA15 HISTONE DEACETYLASE |
AT3G20630 | PredictedAffinity Capture-MS | FSW = 0.0479
| Unknown | UBP14 (UBIQUITIN-SPECIFIC PROTEASE 14) UBIQUITIN-SPECIFIC PROTEASE |
AT3G22480 | PredictedPhenotypic Suppression | FSW = 0.0930
| Unknown | PREFOLDIN-RELATED KE2 FAMILY PROTEIN |
AT3G46960 | PredictedPhenotypic Suppression | FSW = 0.0448
| Unknown | ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING |
AT3G54380 | PredictedPhenotypic Enhancement | FSW = 0.0896
| Unknown | SAC3/GANP FAMILY PROTEIN |
AT4G22140 | PredictedPhenotypic Enhancement | FSW = 0.0848
| Unknown | DNA BINDING / PROTEIN BINDING / ZINC ION BINDING |
AT4G30870 | PredictedPhenotypic Enhancement | FSW = 0.0918
| Unknown | MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING |
AT4G33100 | PredictedPhenotypic Suppression | FSW = 0.0981
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY FAMILY 35/APOPTOSIS (INTERPROIPR007918) HAS 160 BLAST HITS TO 160 PROTEINS IN 70 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 95 FUNGI - 46 PLANTS - 13 VIRUSES - 0 OTHER EUKARYOTES - 6 (SOURCE NCBI BLINK) |
AT5G10260 | PredictedPhenotypic Enhancement | FSW = 0.0883
| Unknown | ATRABH1E (ARABIDOPSIS RAB GTPASE HOMOLOG H1E) GTP BINDING |
AT5G10390 | PredictedPhenotypic Enhancement | FSW = 0.0634
| Unknown | HISTONE H3 |
AT5G23290 | PredictedPhenotypic Suppression | FSW = 0.0188
| Unknown | PDF5 (PREFOLDIN 5) UNFOLDED PROTEIN BINDING |
AT5G38890 | PredictedPhenotypic Suppression | FSW = 0.0173
| Unknown | EXORIBONUCLEASE-RELATED |
AT5G53770 | PredictedPhenotypic EnhancementSynthetic LethalityPhenotypic EnhancementSynthetic Lethality | FSW = 0.0940
| Unknown | NUCLEOTIDYLTRANSFERASE FAMILY PROTEIN |
AT1G07430 | PredictedDosage Growth Defect | FSW = 0.0397
| Unknown | PROTEIN PHOSPHATASE 2C PUTATIVE / PP2C PUTATIVE |
AT1G50490 | PredictedPhenotypic Enhancement | FSW = 0.0155
| Unknown | UBC20 (UBIQUITIN-CONJUGATING ENZYME 20) UBIQUITIN-PROTEIN LIGASE |
AT1G54390 | PredictedPhenotypic Enhancement | FSW = 0.0378
| Unknown | PHD FINGER PROTEIN-RELATED |
AT2G13680 | PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.0352
| Unknown | CALS5 (CALLOSE SYNTHASE 5) 13-BETA-GLUCAN SYNTHASE |
AT3G06910 | PredictedSynthetic Rescue | FSW = 0.0828
| Unknown | ULP1A (UB-LIKE PROTEASE 1A) SUMO-SPECIFIC PROTEASE/ CYSTEINE-TYPE PEPTIDASE |
AT3G25100 | PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.1168
| Unknown | CDC45 (CELL DIVISION CYCLE 45) |
AT3G42660 | PredictedPhenotypic Suppression | FSW = 0.1657
| Unknown | NUCLEOTIDE BINDING |
AT3G57870 | PredictedSynthetic Lethality | FSW = 0.0253
| Unknown | SCE1 (SUMO CONJUGATION ENZYME 1) SUMO LIGASE |
AT3G60240 | PredictedAffinity Capture-MS | FSW = 0.0126
| Unknown | EIF4G (EUKARYOTIC TRANSLATION INITIATION FACTOR 4G) TRANSLATION INITIATION FACTOR |
AT4G33620 | PredictedPhenotypic Enhancement | FSW = 0.0986
| Unknown | ULP1 PROTEASE FAMILY PROTEIN |
AT5G26680 | PredictedSynthetic Rescue | FSW = 0.1163
| Unknown | ENDONUCLEASE PUTATIVE |
AT5G43500 | PredictedPhenotypic Suppression | FSW = 0.1322
| Unknown | ATARP9 (ACTIN-RELATED PROTEIN 9) DNA BINDING / PROTEIN BINDING |
AT5G49010 | PredictedAffinity Capture-MS | FSW = 0.0616
| Unknown | SLD5 (SYNTHETIC LETHALITY WITH DPB11-1 5) |
AT5G61770 | PredictedPhenotypic Suppression | FSW = 0.0308
| Unknown | PPAN (PETER PAN-LIKE PROTEIN) |
AT5G63920 | PredictedSynthetic LethalityPhenotypic Enhancement | FSW = 0.1591
| Unknown | DNA TOPOISOMERASE III ALPHA PUTATIVE |
AT5G66100 | PredictedPhenotypic Suppression | FSW = 0.1030
| Unknown | LA DOMAIN-CONTAINING PROTEIN |
AT3G05250 | Predictedin vitroin vivotwo hybrid | FSW = 0.0580
| Unknown | ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN |
AT5G55300 | PredictedEnriched domain pairPhylogenetic profile methodCo-expression | FSW = 0.4246
| Unknown | TOP1ALPHA (DNA TOPOISOMERASE I ALPHA) DNA TOPOISOMERASE TYPE I |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454