Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G59440 - ( ZEU1 (ZEUS1) ATP binding / thymidylate kinase )

42 Proteins interacs with AT5G59440
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT5G63400

Predicted

Synthetic Rescue

FSW = 0.0311

Unknown

ADK1 (ADENYLATE KINASE 1) ATP BINDING / ADENYLATE KINASE/ NUCLEOBASE NUCLEOSIDE NUCLEOTIDE KINASE/ NUCLEOTIDE KINASE/ PHOSPHOTRANSFERASE PHOSPHATE GROUP AS ACCEPTOR
AT2G30860

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0148

Unknown

ATGSTF9 (GLUTATHIONE S-TRANSFERASE PHI 9) COPPER ION BINDING / GLUTATHIONE BINDING / GLUTATHIONE PEROXIDASE/ GLUTATHIONE TRANSFERASE
AT5G12140

Predicted

Affinity Capture-MS

FSW = 0.5070

Unknown

ATCYS1 (A THALIANA CYSTATIN-1) CYSTEINE-TYPE ENDOPEPTIDASE INHIBITOR
AT2G34480

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.1784

Unknown

60S RIBOSOMAL PROTEIN L18A (RPL18AB)
AT4G01320

Predicted

Affinity Capture-MS

FSW = 0.1804

Unknown

ATSTE24 ENDOPEPTIDASE/ METALLOENDOPEPTIDASE
AT2G30390

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.3663

Unknown

FC2 (FERROCHELATASE 2) FERROCHELATASE
AT3G27850

Predicted

pull down

FSW = 0.0081

Unknown

RPL12-C (RIBOSOMAL PROTEIN L12-C) STRUCTURAL CONSTITUENT OF RIBOSOME
AT3G27300

Predicted

Synthetic Lethality

FSW = 0.0489

Unknown

G6PD5 (GLUCOSE-6-PHOSPHATE DEHYDROGENASE 5) GLUCOSE-6-PHOSPHATE DEHYDROGENASE
ATCG00830Predicted

pull down

FSW = 0.0069

Unknown

ENCODES A CHLOROPLAST RIBOSOMAL PROTEIN L2 A CONSTITUENT OF THE LARGE SUBUNIT OF THE RIBOSOMAL COMPLEX
AT1G11890

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0058

Unknown

SEC22 TRANSPORTER
AT1G75170

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Co-crystal Structure

two hybrid

Co-purification

FSW = 0.3541

Unknown

SEC14 CYTOSOLIC FACTOR FAMILY PROTEIN / PHOSPHOGLYCERIDE TRANSFER FAMILY PROTEIN
AT4G36640

Predicted

Synthetic Rescue

FSW = 0.0298

Unknown

SEC14 CYTOSOLIC FACTOR FAMILY PROTEIN / PHOSPHOGLYCERIDE TRANSFER FAMILY PROTEIN
AT4G35020

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.1907

Unknown

ARAC3 (ARABIDOPSIS RAC-LIKE 3) GTP BINDING / GTPASE
AT1G77210

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.2639

Unknown

SUGAR TRANSPORTER PUTATIVE
AT3G10540

Predicted

Synthetic Lethality

FSW = 0.0522

Unknown

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE PUTATIVE
AT4G33090

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.1610

Unknown

APM1 (AMINOPEPTIDASE M1) AMINOPEPTIDASE
AT3G60180

Predicted

interologs mapping

FSW = 0.0612

Unknown

URIDYLATE KINASE PUTATIVE / URIDINE MONOPHOSPHATE KINASE PUTATIVE / UMP KINASE PUTATIVE
AT4G36590

Predicted

Affinity Capture-MS

FSW = 0.3211

Unknown

MADS-BOX PROTEIN (AGL40)
AT2G40290

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.1293

Unknown

EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 PUTATIVE / EIF-2A PUTATIVE / EIF-2-ALPHA PUTATIVE
AT5G20730

Predicted

Synthetic Lethality

FSW = 0.0198

Unknown

NPH4 (NON-PHOTOTROPHIC HYPOCOTYL) DNA BINDING / TRANSCRIPTION ACTIVATOR/ TRANSCRIPTION FACTOR/ TRANSCRIPTION REGULATOR
AT5G18620

Predicted

Synthetic Lethality

FSW = 0.0243

Unknown

CHR17 (CHROMATIN REMODELING FACTOR17) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ HELICASE/ HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING / NUCLEOSOME BINDING
AT3G06400

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0602

Unknown

CHR11 (CHROMATIN-REMODELING PROTEIN 11) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ HELICASE/ HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING / NUCLEOSOME BINDING
AT5G47630

Predicted

Affinity Capture-MS

FSW = 0.1633

Unknown

MTACP3 (MITOCHONDRIAL ACYL CARRIER PROTEIN 3) ACYL CARRIER/ COFACTOR BINDING
AT4G02930

Predicted

pull down

FSW = 0.0044

Unknown

ELONGATION FACTOR TU PUTATIVE / EF-TU PUTATIVE
AT5G66130

Predicted

Synthetic Lethality

FSW = 0.0313

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT5G40760

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0326

Unknown

G6PD6 (GLUCOSE-6-PHOSPHATE DEHYDROGENASE 6) GLUCOSE-6-PHOSPHATE DEHYDROGENASE
AT5G20850

Predicted

Phenotypic Enhancement

FSW = 0.0245

Unknown

ATRAD51 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING / SEQUENCE-SPECIFIC DNA BINDING
AT3G12280

Predicted

Phenotypic Enhancement

FSW = 0.0072

Unknown

RBR1 (RETINOBLASTOMA-RELATED 1) TRANSCRIPTION FACTOR BINDING
AT1G10600

Predicted

Affinity Capture-MS

Affinity Capture-MS

Co-crystal Structure

FSW = 0.3979

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS LOCATED IN CHLOROPLAST EXPRESSED IN CULTURED CELL CONTAINS INTERPRO DOMAIN/S MOV34/MPN/PAD-1 (INTERPROIPR000555) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT4G161441) HAS 753 BLAST HITS TO 752 PROTEINS IN 167 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 359 FUNGI - 199 PLANTS - 115 VIRUSES - 0 OTHER EUKARYOTES - 80 (SOURCE NCBI BLINK)
AT1G10930

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0341

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT1G24290

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0496

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT1G43080

Predicted

Affinity Capture-MS

Affinity Capture-MS

Co-crystal Structure

FSW = 0.4281

Unknown

GLYCOSIDE HYDROLASE FAMILY 28 PROTEIN / POLYGALACTURONASE (PECTINASE) FAMILY PROTEIN
AT3G30842

Predicted

Affinity Capture-MS

two hybrid

Affinity Capture-MS

Co-crystal Structure

synthetic growth defect

FSW = 0.1345

Unknown

PDR10 (PLEIOTROPIC DRUG RESISTANCE 10) ATP BINDING / ATPASE/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT5G04510

Predicted

Synthetic Lethality

FSW = 0.0290

Unknown

PDK1 (3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1) 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE/ KINASE/ PHOSPHOINOSITIDE BINDING / PROTEIN BINDING / PROTEIN KINASE
AT5G26667

Predicted

interologs mapping

FSW = 0.0973

Unknown

PYR6 CYTIDYLATE KINASE/ URIDYLATE KINASE
AT5G26680

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0172

Unknown

ENDONUCLEASE PUTATIVE
AT1G54390

Predicted

Phenotypic Enhancement

FSW = 0.0119

Unknown

PHD FINGER PROTEIN-RELATED
AT2G47970

Predicted

Affinity Capture-MS

FSW = 0.2501

Unknown

NPL4 FAMILY PROTEIN
AT3G18660

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0582

Unknown

PGSIP1 (PLANT GLYCOGENIN-LIKE STARCH INITIATION PROTEIN 1) TRANSFERASE TRANSFERRING GLYCOSYL GROUPS
AT5G66610

Predicted

two hybrid

FSW = 0.0201

Unknown

DAR7 (DA1-RELATED PROTEIN 7) ZINC ION BINDING
AT5G63920

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0643

Unknown

DNA TOPOISOMERASE III ALPHA PUTATIVE
AT4G11080

Predicted

Synthetic Lethality

interaction prediction

FSW = 0.0489

Unknown

HIGH MOBILITY GROUP (HMG1/2) FAMILY PROTEIN

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454