Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G66020 - ( ATSAC1B (SUPPRESSOR OF ACTIN 1B) phosphatidylinositol-45-bisphosphate 5-phosphatase )

72 Proteins interacs with AT5G66020
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT5G23630

Predicted

Phenotypic Enhancement

FSW = 0.1330

Class C:

endoplasmic reticulum

ATPASE E1-E2 TYPE FAMILY PROTEIN / HALOACID DEHALOGENASE-LIKE HYDROLASE FAMILIY PROTEIN
AT3G51460

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.3691

Class C:

endoplasmic reticulum

RHD4 (ROOT HAIR DEFECTIVE4) PHOSPHATIDYLINOSITOL-45-BISPHOSPHATE 5-PHOSPHATASE/ PHOSPHATIDYLINOSITOL-4-PHOSPHATE PHOSPHATASE
AT4G21180

Predicted

Phenotypic Enhancement

FSW = 0.0244

Class C:

endoplasmic reticulum

ATERDJ2B HEAT SHOCK PROTEIN BINDING / UNFOLDED PROTEIN BINDING
AT5G05670

Predicted

two hybrid

FSW = 0.0675

Class C:

endoplasmic reticulum

SIGNAL RECOGNITION PARTICLE BINDING
AT3G51830

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.0272

Class C:

endoplasmic reticulum

ATG5 PHOSPHATIDYLINOSITOL-45-BISPHOSPHATE 5-PHOSPHATASE
AT1G22200

Predicted

Phenotypic Enhancement

FSW = 0.0297

Class C:

endoplasmic reticulum

UNKNOWN PROTEIN
AT3G05710

Predicted

Phenotypic Enhancement

FSW = 0.0980

Class C:

endoplasmic reticulum

SYP43 (SYNTAXIN OF PLANTS 43) SNAP RECEPTOR
AT1G67730

Predicted

two hybrid

FSW = 0.0518

Class C:

endoplasmic reticulum

YBR159 KETOREDUCTASE/ OXIDOREDUCTASE
AT5G09590

Predicted

Phenotypic Enhancement

FSW = 0.0243

Unknown

MTHSC70-2 (MITOCHONDRIAL HSP70 2) ATP BINDING
AT3G56190

Predicted

synthetic growth defect

FSW = 0.0042

Unknown

ALPHA-SNAP2 (ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN 2) BINDING / SOLUBLE NSF ATTACHMENT PROTEIN
AT1G12360

Predicted

Synthetic Rescue

FSW = 0.0247

Unknown

KEU (KEULE) PROTEIN TRANSPORTER
AT1G31780

Predicted

Phenotypic Enhancement

FSW = 0.1121

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 24 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S CONSERVED OLIGOMERIC COMPLEX COG6 (INTERPROIPR010490) HAS 281 BLAST HITS TO 279 PROTEINS IN 131 SPECIES ARCHAE - 0 BACTERIA - 2 METAZOA - 132 FUNGI - 106 PLANTS - 21 VIRUSES - 0 OTHER EUKARYOTES - 20 (SOURCE NCBI BLINK)
AT2G30710

Predicted

Phenotypic Enhancement

FSW = 0.1099

Unknown

RABGAP/TBC DOMAIN-CONTAINING PROTEIN
AT3G62870

Predicted

synthetic growth defect

FSW = 0.0120

Unknown

60S RIBOSOMAL PROTEIN L7A (RPL7AB)
AT5G26030

Predicted

two hybrid

FSW = 0.0035

Unknown

FC1 (FERROCHELATASE 1) FERROCHELATASE
AT1G32470

Predicted

Phenotypic Enhancement

FSW = 0.0308

Unknown

GLYCINE CLEAVAGE SYSTEM H PROTEIN MITOCHONDRIAL PUTATIVE
AT3G23940

Predicted

Affinity Capture-MS

FSW = 0.0146

Unknown

DEHYDRATASE FAMILY
AT1G07420

Predicted

Phenotypic Enhancement

FSW = 0.0590

Unknown

SMO2-1 (STEROL 4-ALPHA-METHYL-OXIDASE 2-1) 4-ALPHA-METHYL-DELTA7-STEROL-4ALPHA-METHYL OXIDASE/ C-4 METHYLSTEROL OXIDASE
AT1G49340

Predicted

Phenotypic Suppression

Synthetic Rescue

FSW = 0.0701

Unknown

ATPI4K ALPHA 1-PHOSPHATIDYLINOSITOL 4-KINASE/ INOSITOL OR PHOSPHATIDYLINOSITOL KINASE
AT3G12110

Predicted

Synthetic Rescue

FSW = 0.0344

Unknown

ACT11 (ACTIN-11) STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT5G52640

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.0299

Unknown

ATHSP901 (HEAT SHOCK PROTEIN 901) ATP BINDING / UNFOLDED PROTEIN BINDING
AT4G34580

Predicted

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

FSW = 0.0557

Unknown

COW1 (CAN OF WORMS1) PHOSPHATIDYLINOSITOL TRANSPORTER/ TRANSPORTER
AT2G19830

Predicted

Synthetic Lethality

FSW = 0.0346

Unknown

SNF72
AT1G08820

Predicted

two hybrid

Phenotypic Enhancement

FSW = 0.0645

Unknown

VAP27-2 (VAMP/SYNAPTOBREVIN-ASSOCIATED PROTEIN 27-2) STRUCTURAL MOLECULE
AT1G71820

Predicted

Synthetic Rescue

FSW = 0.0414

Unknown

SEC6
AT2G44680

Predicted

Phenotypic Enhancement

FSW = 0.0591

Unknown

CKB4 (CASEIN KINASE II BETA SUBUNIT 4) PROTEIN SERINE/THREONINE KINASE
AT3G57660

Predicted

Phenotypic Enhancement

FSW = 0.0048

Unknown

NRPA1 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ ZINC ION BINDING
AT2G06210

Predicted

Phenotypic Enhancement

FSW = 0.0729

Unknown

ELF8 (EARLY FLOWERING 8) BINDING
AT5G37720

Predicted

Affinity Capture-MS

FSW = 0.0171

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT2G24500

Predicted

Phenotypic Enhancement

FSW = 0.0396

Unknown

FZF TRANSCRIPTION FACTOR
AT2G38560

Predicted

Phenotypic Enhancement

FSW = 0.0661

Unknown

TFIIS (TRANSCRIPT ELONGATION FACTOR IIS) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION ELONGATION FACTOR/ TRANSCRIPTION FACTOR
AT2G44950

Predicted

synthetic growth defect

FSW = 0.1203

Unknown

HUB1 (HISTONE MONO-UBIQUITINATION 1) PROTEIN BINDING / PROTEIN HOMODIMERIZATION/ UBIQUITIN-PROTEIN LIGASE/ ZINC ION BINDING
AT5G38460

Predicted

Phenotypic Enhancement

FSW = 0.1303

Unknown

ALG6 ALG8 GLYCOSYLTRANSFERASE FAMILY PROTEIN
AT5G50720

Predicted

two hybrid

FSW = 0.0675

Unknown

ATHVA22E
AT1G07430

Predicted

Synthetic Lethality

FSW = 0.0832

Unknown

PROTEIN PHOSPHATASE 2C PUTATIVE / PP2C PUTATIVE
AT1G20575

Predicted

Colocalization

FSW = 0.0771

Unknown

DOLICHYL-PHOSPHATE BETA-D-MANNOSYLTRANSFERASE PUTATIVE / DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE PUTATIVE / MANNOSE-P-DOLICHOL SYNTHASE PUTATIVE
AT1G49540

Predicted

Phenotypic Enhancement

FSW = 0.0686

Unknown

NUCLEOTIDE BINDING
AT1G60490

Predicted

Synthetic Lethality

FSW = 0.0414

Unknown

ATVPS34 1-PHOSPHATIDYLINOSITOL-3-KINASE/ BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR
AT1G69640

Predicted

Phenotypic Enhancement

FSW = 0.1372

Unknown

SBH1 (SPHINGOID BASE HYDROXYLASE 1) CATALYTIC/ SPHINGOSINE HYDROXYLASE
AT1G79730

Predicted

Phenotypic Enhancement

FSW = 0.1149

Unknown

ELF7 (EARLY FLOWERING 7)
AT1G80500

Predicted

Phenotypic Enhancement

FSW = 0.0581

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN TRANSPORT ER TO GOLGI VESICLE-MEDIATED TRANSPORT LOCATED IN INTRACELLULAR EXPRESSED IN 24 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S SEDLIN (INTERPROIPR006722) LONGIN-LIKE (INTERPROIPR011012) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT2G209301) HAS 437 BLAST HITS TO 435 PROTEINS IN 138 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 248 FUNGI - 75 PLANTS - 53 VIRUSES - 0 OTHER EUKARYOTES - 61 (SOURCE NCBI BLINK)
AT2G15230

Predicted

Phenotypic Enhancement

FSW = 0.0442

Unknown

ATLIP1 (ARABIDOPSIS THALIANA LIPASE 1) GALACTOLIPASE/ HYDROLASE/ PHOSPHOLIPASE/ TRIACYLGLYCEROL LIPASE
AT2G22530

Predicted

Phenotypic Enhancement

FSW = 0.0960

Unknown

CATALYTIC/ TRANSFERASE
AT3G06460

Predicted

two hybrid

FSW = 0.0753

Unknown

GNS1/SUR4 MEMBRANE FAMILY PROTEIN
AT3G21060

Predicted

Phenotypic Enhancement

FSW = 0.0873

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G54380

Predicted

Phenotypic Suppression

FSW = 0.0735

Unknown

SAC3/GANP FAMILY PROTEIN
AT4G12460

Predicted

Phenotypic Enhancement

FSW = 0.0427

Unknown

ORP2B (OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 2B) OXYSTEROL BINDING
AT4G33240

Predicted

Synthetic Lethality

FSW = 0.1173

Unknown

1-PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE/ ATP BINDING / PHOSPHATIDYLINOSITOL PHOSPHATE KINASE/ PROTEIN BINDING / ZINC ION BINDING
AT5G01770

Predicted

Phenotypic Enhancement

FSW = 0.0073

Unknown

RAPTOR2 (RAPTOR2) BINDING / NUCLEOTIDE BINDING
AT5G27970Predicted

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1217

Unknown

BINDING
AT1G08750

Predicted

two hybrid

FSW = 0.1252

Unknown

GPI-ANCHOR TRANSAMIDASE PUTATIVE
AT1G80410

Predicted

synthetic growth defect

FSW = 0.0581

Unknown

EMB2753 (EMBRYO DEFECTIVE 2753) BINDING
AT2G02760

Predicted

synthetic growth defect

FSW = 0.0843

Unknown

ATUBC2 (UBIQUITING-CONJUGATING ENZYME 2) UBIQUITIN-PROTEIN LIGASE
AT2G16950

Predicted

Affinity Capture-MS

FSW = 0.0049

Unknown

TRN1 (TRANSPORTIN 1) PROTEIN TRANSPORTER
AT2G23070

Predicted

Phenotypic Enhancement

FSW = 0.0408

Unknown

CASEIN KINASE II ALPHA CHAIN PUTATIVE
AT3G01340

Predicted

Synthetic Lethality

FSW = 0.0366

Unknown

PROTEIN TRANSPORT PROTEIN SEC13 FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G18430

Predicted

Synthetic Lethality

FSW = 0.0247

Unknown

CALCIUM-BINDING EF HAND FAMILY PROTEIN
AT3G25900

Predicted

Phenotypic Enhancement

FSW = 0.0108

Unknown

HMT-1 HOMOCYSTEINE S-METHYLTRANSFERASE
AT3G58560

Predicted

Synthetic Lethality

FSW = 0.0597

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT4G14160

Predicted

synthetic growth defect

FSW = 0.0298

Unknown

TRANSPORT PROTEIN PUTATIVE
AT4G35620

Predicted

Affinity Capture-MS

FSW = 0.0135

Unknown

CYCB22 (CYCLIN B22) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT5G10260

Predicted

Phenotypic Enhancement

FSW = 0.1327

Unknown

ATRABH1E (ARABIDOPSIS RAB GTPASE HOMOLOG H1E) GTP BINDING
AT5G10960

Predicted

Synthetic Lethality

FSW = 0.0438

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT5G13780

Predicted

synthetic growth defect

FSW = 0.0953

Unknown

GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE
AT5G16040

Predicted

two hybrid

FSW = 0.0043

Unknown

REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY PROTEIN
AT5G23290

Predicted

Phenotypic Suppression

FSW = 0.0609

Unknown

PDF5 (PREFOLDIN 5) UNFOLDED PROTEIN BINDING
AT5G26680

Predicted

synthetic growth defect

FSW = 0.0568

Unknown

ENDONUCLEASE PUTATIVE
AT5G45600

Predicted

Phenotypic Enhancement

FSW = 0.1646

Unknown

GAS41 PROTEIN BINDING
AT5G50320

Predicted

Phenotypic Enhancement

FSW = 0.0588

Unknown

ELO3 (ELONGATA 3) HISTONE ACETYLTRANSFERASE
AT5G52210

Predicted

Phenotypic Enhancement

FSW = 0.0819

Unknown

ATGB1 (ARABIDOPSIS THALIANA GTP-BINDING PROTEIN 1) GTP BINDING
AT5G61150

Predicted

Phenotypic Enhancement

FSW = 0.0507

Unknown

VIP4 (VERNALIZATION INDEPENDENCE 4) PROTEIN BINDING
AT5G67320

Predicted

Phenotypic Enhancement

FSW = 0.0240

Unknown

HOS15 (HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 15)

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454