Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G59880 - ( ADF3 (ACTIN DEPOLYMERIZING FACTOR 3) actin binding )

16 Proteins interacs with AT5G59880
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G35670

Experimental

two hybrid

FSW = 0.0183

Class A:

plasma membrane

Class B:

nucleus

mitochondrion

cytosol

Class D:

cytosol (p = 0.67)

ATCDPK2 (CALCIUM-DEPENDENT PROTEIN KINASE 2) CALMODULIN-DEPENDENT PROTEIN KINASE/ KINASE
AT3G05420

Experimental

FSW = 0.0526

Class A:

plasma membrane

Class B:

mitochondrion

cytosol

ACBP4 (ACYL-COA BINDING PROTEIN 4) ACYL-COA BINDING
AT3G58730

Predicted

interologs mapping

FSW = 0.0211

Class C:

plasma membrane

VACUOLAR ATP SYNTHASE SUBUNIT D (VATD) / V-ATPASE D SUBUNIT / VACUOLAR PROTON PUMP D SUBUNIT (VATPD)
AT3G46000

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.7878

Class C:

plasma membrane

ADF2 (ACTIN DEPOLYMERIZING FACTOR 2) ACTIN BINDING
AT3G47520

Predicted

Phenotypic Suppression

FSW = 0.0140

Class C:

mitochondrion

MDH (MALATE DEHYDROGENASE) L-MALATE DEHYDROGENASE/ BINDING / CATALYTIC/ MALATE DEHYDROGENASE/ OXIDOREDUCTASE/ OXIDOREDUCTASE ACTING ON THE CH-OH GROUP OF DONORS NAD OR NADP AS ACCEPTOR
AT2G31200

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.3748

Unknown

ADF6 (ACTIN DEPOLYMERIZING FACTOR 6) ACTIN BINDING
AT2G16700

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.7356

Unknown

ADF5 (ACTIN DEPOLYMERIZING FACTOR 5) ACTIN BINDING
AT3G46010

Predicted

Gene fusion method

Phylogenetic profile method

Co-expression

FSW = 0.5675

Unknown

ADF1 (ACTIN DEPOLYMERIZING FACTOR 1) ACTIN BINDING
AT1G61670

Predicted

Phenotypic Suppression

FSW = 0.0321

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN LOCATED IN ENDOMEMBRANE SYSTEM INTEGRAL TO MEMBRANE CONTAINS INTERPRO DOMAIN/S TRANSMEMBRANE RECEPTOR EUKARYOTA (INTERPROIPR009637) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT1G109801) HAS 473 BLAST HITS TO 471 PROTEINS IN 125 SPECIES ARCHAE - 0 BACTERIA - 2 METAZOA - 242 FUNGI - 99 PLANTS - 92 VIRUSES - 0 OTHER EUKARYOTES - 38 (SOURCE NCBI BLINK)
AT5G59890

Predicted

Gene fusion method

Gene neighbors method

Phylogenetic profile method

Co-expression

FSW = 0.2837

Unknown

ADF4 (ACTIN DEPOLYMERIZING FACTOR 4) ACTIN BINDING
AT5G52360

Predicted

Gene neighbors method

Phylogenetic profile method

Co-expression

FSW = 0.7878

Unknown

ADF10 (ACTIN DEPOLYMERIZING FACTOR 10) ACTIN BINDING
AT4G25590

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.7878

Unknown

ADF7 (ACTIN DEPOLYMERIZING FACTOR 7) ACTIN BINDING
AT4G34970

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.7878

Unknown

ADF9 (ACTIN DEPOLYMERIZING FACTOR 9) ACTIN BINDING
AT4G00680

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.7878

Unknown

ADF8 (ACTIN DEPOLYMERIZING FACTOR 8) ACTIN BINDING
AT1G01750

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.4619

Unknown

ADF11 (ACTIN DEPOLYMERIZING FACTOR 11) ACTIN BINDING
AT3G45990

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.7878

Unknown

ACTIN-DEPOLYMERIZING FACTOR PUTATIVE

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Fasta sequences:

Proteins

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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454