Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G46210 - ( CUL4 (CULLIN4) protein binding / ubiquitin-protein ligase )

20 Proteins interacs with AT5G46210
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT2G02560

Experimental

two hybrid

Affinity Capture-Western

affinity technology

FSW = 0.1214

Unknown

CAND1 (CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED) BINDING
AT2G32950

Experimental

Affinity Capture-Western

Affinity Capture-Western

affinity technology

FSW = 0.1576

Unknown

COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT4G10180

Experimental

Affinity Capture-Western

Reconstituted Complex

Affinity Capture-Western

co-fractionation

Co-fractionation

in vitro

affinity technology

FSW = 0.5193

Unknown

DET1 (DE-ETIOLATED 1) CATALYTIC
AT4G21100

Experimental

Affinity Capture-Western

pull down

Reconstituted Complex

Affinity Capture-Western

in vitro

FSW = 0.3600

Unknown

DDB1B (DAMAGED DNA BINDING PROTEIN 1 B) DAMAGED DNA BINDING / PROTEIN BINDING
AT4G05420

Experimental

two hybrid

in vitro

two hybrid

Reconstituted Complex

pull down

pull down

pull down

Affinity Capture-Western

FSW = 0.3584

Unknown

DDB1A (DAMAGED DNA BINDING PROTEIN 1A) DNA BINDING / PROTEIN BINDING
AT3G13550

Experimental

molecular sieving

two hybrid

Affinity Capture-Western

affinity technology

FSW = 0.2077

Unknown

FUS9 (FUSCA 9) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT5G20570

Experimental

two hybrid

two hybrid

pull down

Affinity Capture-Western

affinity technology

two hybrid

FSW = 0.0874

Unknown

RBX1 (RING-BOX 1) PROTEIN BINDING
AT5G42970

Experimental

Affinity Capture-Western

affinity technology

FSW = 0.2348

Unknown

COP8 (CONSTITUTIVE PHOTOMORPHOGENIC 8) PROTEIN BINDING
AT1G71230

Experimental

FSW = 0.1441

Unknown

CSN5B (COP9-SIGNALOSOME 5B) PROTEIN BINDING
AT4G15900

Experimental

Affinity Capture-Western

FSW = 0.0229

Unknown

PRL1 (PLEIOTROPIC REGULATORY LOCUS 1) BASAL TRANSCRIPTION REPRESSOR/ NUCLEOTIDE BINDING / PROTEIN BINDING
AT5G14250

Experimental

Affinity Capture-Western

affinity technology

FSW = 0.2258

Unknown

COP13 (CONSTITUTIVE PHOTOMORPHOGENIC 13) PROTEIN BINDING
AT4G14110

Experimental

FSW = 0.2424

Unknown

COP9 (CONSTITUTIVE PHOTOMORPHOGENIC 9) METALLOENDOPEPTIDASE/ PROTEIN BINDING
AT5G58760

Experimental

FSW = 0.2844

Unknown

DDB2 (DAMAGED DNA-BINDING 2) NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING
AT4G31160

Experimental

FSW = 0.0683

Unknown

DCAF1 (DDB1-CUL4 ASSOCIATED FACTOR 1) NUCLEOTIDE BINDING
AT1G02980

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.1254

Unknown

CUL2 (CULLIN 2) UBIQUITIN PROTEIN LIGASE BINDING
AT3G27640

Predicted

Affinity Capture-MS

FSW = 0.1219

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT4G13460

Predicted

Colocalization

Affinity Capture-Western

FSW = 0.0696

Unknown

SUVH9 HISTONE-LYSINE N-METHYLTRANSFERASE/ ZINC ION BINDING
AT4G02570

Predicted

Shared biological function

Phylogenetic profile method

Co-expression

FSW = 0.0707

Unknown

ATCUL1 (ARABIDOPSIS THALIANA CULLIN 1) PROTEIN BINDING
AT4G11110

Predicted

Affinity Capture-Western

FSW = 0.2963

Unknown

SPA2 (SPA1-RELATED 2) PROTEIN BINDING / SIGNAL TRANSDUCER
AT1G26830

Predicted

Shared biological function

Phylogenetic profile method

Co-expression

FSW = 0.1318

Unknown

ATCUL3 (ARABIDOPSIS THALIANA CULLIN 3) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE

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Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454