Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT1G21690 - ( emb1968 (embryo defective 1968) ATP binding / ATPase/ DNA binding / DNA clamp loader/ nucleoside-triphosphatase/ nucleotide binding )

28 Proteins interacs with AT1G21690
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT2G33040

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0166

Class C:

nucleus

ATP SYNTHASE GAMMA CHAIN MITOCHONDRIAL (ATPC)
AT1G20960

Predicted

Affinity Capture-MS

interaction prediction

Co-expression

FSW = 0.0065

Class C:

nucleus

EMB1507 (EMBRYO DEFECTIVE 1507) ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT1G08130

Predicted

Affinity Capture-Western

FSW = 0.2849

Class C:

nucleus

ATLIG1 (ARABIDOPSIS THALIANA DNA LIGASE 1) ATP BINDING / DNA BINDING / DNA LIGASE (ATP)
AT3G06720

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0087

Class C:

nucleus

IMPA-1 (IMPORTIN ALPHA ISOFORM 1) BINDING / PROTEIN TRANSPORTER
AT4G38130

Predicted

Affinity Capture-MS

in vivo

Co-expression

FSW = 0.0310

Class C:

nucleus

HD1 (HISTONE DEACETYLASE 1) BASAL TRANSCRIPTION REPRESSOR/ HISTONE DEACETYLASE/ PROTEIN BINDING
AT2G29570

Predicted

in vivo

in vivo

in vitro

in vitro

Affinity Capture-MS

Co-expression

FSW = 0.2120

Class C:

nucleus

PCNA2 (PROLIFERATING CELL NUCLEAR ANTIGEN 2) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR
AT1G07370

Predicted

Synthetic Rescue

Reconstituted Complex

Reconstituted Complex

interaction prediction

Co-expression

FSW = 0.1293

Class C:

nucleus

PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING
AT1G06230

Predicted

in vitro

FSW = 0.0919

Class C:

nucleus

GTE4 (GLOBAL TRANSCRIPTION FACTOR GROUP E 4) DNA BINDING
AT1G23190

Predicted

Affinity Capture-MS

FSW = 0.0462

Unknown

PHOSPHOGLUCOMUTASE CYTOPLASMIC PUTATIVE / GLUCOSE PHOSPHOMUTASE PUTATIVE
AT1G18080

Predicted

Gene fusion method

FSW = 0.0176

Unknown

ATARCA NUCLEOTIDE BINDING
AT1G09830

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0662

Unknown

PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (PUR2)
AT5G51820

Predicted

Affinity Capture-MS

FSW = 0.0143

Unknown

PGM (PHOSPHOGLUCOMUTASE) PHOSPHOGLUCOMUTASE
AT1G70730

Predicted

interaction prediction

FSW = 0.0693

Unknown

PHOSPHOGLUCOMUTASE CYTOPLASMIC PUTATIVE / GLUCOSE PHOSPHOMUTASE PUTATIVE
AT5G19330

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0194

Unknown

ARMADILLO/BETA-CATENIN REPEAT FAMILY PROTEIN / BTB/POZ DOMAIN-CONTAINING PROTEIN
AT5G48970

Predicted

Gene fusion method

FSW = 0.0246

Unknown

MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN
AT2G31970

Predicted

Synthetic Lethality

Co-expression

FSW = 0.0561

Unknown

RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING
AT5G66130

Predicted

two hybrid

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Reconstituted Complex

Reconstituted Complex

Affinity Capture-MS

Affinity Capture-MS

Reconstituted Complex

in vivo

Co-purification

Co-expression

FSW = 0.1986

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT5G63960

Predicted

Synthetic Lethality

interaction prediction

Co-expression

FSW = 0.1179

Unknown

EMB2780 (EMBRYO DEFECTIVE 2780) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING
AT5G22010

Predicted

two hybrid

Synthetic Lethality

Co-purification

Co-purification

Co-purification

Co-purification

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.3575

Unknown

ATRFC1 (REPLICATION FACTOR C 1) ATP BINDING / DNA BINDING / DNA CLAMP LOADER/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT5G27740

Predicted

interaction prediction

two hybrid

two hybrid

Synthetic Lethality

Synthetic Lethality

Reconstituted Complex

in vivo

in vivo

in vitro

in vitro

interologs mapping

Co-purification

Co-purification

Co-purification

Co-purification

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Co-expression

FSW = 0.1704

Unknown

EMB2775 (EMBRYO DEFECTIVE 2775) DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT1G77470

Predicted

two hybrid

two hybrid

Reconstituted Complex

in vivo

in vitro

Co-purification

Co-purification

Co-purification

Co-purification

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

two hybrid

interaction prediction

Gene neighbors method

Phylogenetic profile method

Co-expression

FSW = 0.2951

Unknown

REPLICATION FACTOR C 36 KDA PUTATIVE
AT1G04730Predicted

Reconstituted Complex

Affinity Capture-Western

Affinity Capture-Western

in vivo

Affinity Capture-MS

Reconstituted Complex

Co-purification

interaction prediction

Co-expression

FSW = 0.1270

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT1G08260

Predicted

Synthetic Lethality

Co-expression

FSW = 0.0824

Unknown

TIL1 (TILTED 1) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING
AT1G63160

Predicted

Co-purification

Co-purification

Co-purification

Co-purification

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

Gene neighbors method

Phylogenetic profile method

Co-expression

FSW = 0.2129

Unknown

REPLICATION FACTOR C 40 KDA PUTATIVE
AT1G66740

Predicted

Affinity Capture-Western

FSW = 0.0751

Unknown

SGA2
AT5G13060

Predicted

Affinity Capture-MS

FSW = 0.0363

Unknown

ABAP1 (ARMADILLO BTB ARABIDOPSIS PROTEIN 1) PROTEIN BINDING
AT1G02690

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0094

Unknown

IMPA-6 (IMPORTIN ALPHA ISOFORM 6) BINDING / PROTEIN TRANSPORTER
AT2G27120

Predicted

interaction prediction

FSW = 0.1815

Unknown

TIL2 (TILTED 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454