Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G27740 - ( EMB2775 (EMBRYO DEFECTIVE 2775) DNA binding / nucleoside-triphosphatase/ nucleotide binding )
59 Proteins interacs with AT5G27740Locus | Method | FSW | Cellular Compartment Classification (C3) | Description |
---|---|---|---|---|
AT5G06680 | PredictedSynthetic LethalityCo-expression | FSW = 0.0161
| Unknown | SPC98 (SPINDLE POLE BODY COMPONENT 98) TUBULIN BINDING |
AT3G18524 | PredictedPhenotypic Suppression | FSW = 0.0733
| Unknown | MSH2 (MUTS HOMOLOG 2) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING |
AT1G16970 | PredictedPhenotypic EnhancementCo-expression | FSW = 0.0509
| Unknown | KU70 (ARABIDOPSIS THALIANA KU70 HOMOLOG) DOUBLE-STRANDED DNA BINDING / PROTEIN BINDING |
AT1G08130 | PredictedSynthetic LethalityAffinity Capture-WesternCo-expression | FSW = 0.1587
| Unknown | ATLIG1 (ARABIDOPSIS THALIANA DNA LIGASE 1) ATP BINDING / DNA BINDING / DNA LIGASE (ATP) |
AT2G15240 | Predictedinterologs mapping | FSW = 0.0286
| Unknown | UNC-50 FAMILY PROTEIN |
AT4G16830 | PredictedAffinity Capture-MS | FSW = 0.0074
| Unknown | NUCLEAR RNA-BINDING PROTEIN (RGGA) |
AT5G67270 | PredictedPhenotypic Enhancement | FSW = 0.1278
| Unknown | ATEB1C (MICROTUBULE END BINDING PROTEIN 1) MICROTUBULE BINDING |
AT2G24490 | PredictedSynthetic LethalityCo-expression | FSW = 0.1111
| Unknown | RPA2 (REPLICON PROTEIN A2) PROTEIN BINDING |
AT1G21690 | Predictedinteraction predictiontwo hybridtwo hybridSynthetic LethalitySynthetic LethalityReconstituted Complexin vivoin vivoin vitroin vitrointerologs mappingCo-purificationCo-purificationCo-purificationCo-purificationAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSCo-expression | FSW = 0.1704
| Unknown | EMB1968 (EMBRYO DEFECTIVE 1968) ATP BINDING / ATPASE/ DNA BINDING / DNA CLAMP LOADER/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING |
AT3G20740 | Predictedtwo hybrid | FSW = 0.0092
| Unknown | FIE (FERTILIZATION-INDEPENDENT ENDOSPERM) NUCLEOTIDE BINDING / TRANSCRIPTION FACTOR/ TRANSCRIPTION REGULATOR |
AT3G54280 | PredictedSynthetic Lethality | FSW = 0.0054
| Unknown | RGD3 (ROOT GROWTH DEFECTIVE 3) ATP BINDING / DNA BINDING / BINDING / HELICASE/ NUCLEIC ACID BINDING |
AT2G29570 | Predictedin vitroin vitroAffinity Capture-WesternCo-expression | FSW = 0.1531
| Unknown | PCNA2 (PROLIFERATING CELL NUCLEAR ANTIGEN 2) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR |
AT1G07370 | Predictedinteraction predictionSynthetic LethalityReconstituted Complexinterologs mappinginterologs mappingReconstituted Complexinterologs mappinginterologs mappingCo-expression | FSW = 0.2548
| Unknown | PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING |
AT1G65470 | PredictedPhenotypic Enhancement | FSW = 0.2374
| Unknown | FAS1 (FASCIATA 1) HISTONE BINDING |
AT3G19210 | PredictedPhenotypic Enhancement | FSW = 0.1786
| Unknown | ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING |
AT4G22380 | PredictedAffinity Capture-MS | FSW = 0.0394
| Unknown | RIBOSOMAL PROTEIN L7AE/L30E/S12E/GADD45 FAMILY PROTEIN |
AT1G67630 | PredictedAffinity Capture-MSAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0752
| Unknown | POLA2 (DNA POLYMERASE ALPHA 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE |
AT4G31180 | PredictedSynthetic Lethality | FSW = 0.0220
| Unknown | ASPARTYL-TRNA SYNTHETASE PUTATIVE / ASPARTATE--TRNA LIGASE PUTATIVE |
AT5G66130 | PredictedAffinity Capture-WesternAffinity Capture-WesternReconstituted ComplexReconstituted Complexin vivoAffinity Capture-MSCo-purificationco-fractionationCo-fractionationinterologs mapping | FSW = 0.2603
| Unknown | ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE) |
AT3G23890 | PredictedAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0285
| Unknown | TOPII (TOPOISOMERASE II) ATP BINDING / DNA BINDING / DNA TOPOISOMERASE (ATP-HYDROLYZING)/ DNA TOPOISOMERASE/ DNA-DEPENDENT ATPASE |
AT5G57450 | PredictedPhenotypic Enhancement | FSW = 0.1668
| Unknown | XRCC3 ATP BINDING / DAMAGED DNA BINDING / PROTEIN BINDING / SINGLE-STRANDED DNA BINDING |
AT1G48160 | PredictedAffinity Capture-MS | FSW = 0.0092
| Unknown | SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN PUTATIVE / SRP19 PUTATIVE |
AT5G20850 | PredictedPhenotypic Enhancement | FSW = 0.1241
| Unknown | ATRAD51 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING / SEQUENCE-SPECIFIC DNA BINDING |
AT5G22010 | Predictedtwo hybridSynthetic Rescuein vivoin vivoin vitroin vitroAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSSynthetic RescueAffinity Capture-MSinteraction prediction | FSW = 0.1852
| Unknown | ATRFC1 (REPLICATION FACTOR C 1) ATP BINDING / DNA BINDING / DNA CLAMP LOADER/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING |
AT1G04730 | PredictedReconstituted ComplexPhenotypic EnhancementAffinity Capture-WesternAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSPhenotypic EnhancementAffinity Capture-WesternAffinity Capture-MSReconstituted ComplexCo-purificationinteraction predictionCo-expression | FSW = 0.1720
| Unknown | AAA-TYPE ATPASE FAMILY PROTEIN |
AT1G04160 | PredictedSynthetic Lethality | FSW = 0.0037
| Unknown | XIB (MYOSIN XI B) MOTOR |
AT1G24290 | Predictedinterologs mapping | FSW = 0.0507
| Unknown | AAA-TYPE ATPASE FAMILY PROTEIN |
AT1G63160 | PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.3311
| Unknown | REPLICATION FACTOR C 40 KDA PUTATIVE |
AT1G66740 | PredictedPhenotypic EnhancementAffinity Capture-WesternPhenotypic Enhancement | FSW = 0.1471
| Unknown | SGA2 |
AT1G68310 | PredictedSynthetic Lethality | FSW = 0.0179
| Unknown | VACUOLAR SORTING SIGNAL BINDING |
AT1G69070 | PredictedSynthetic LethalityCo-expression | FSW = 0.0039
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S NOP14-LIKE PROTEIN (INTERPROIPR007276) HAS 64668 BLAST HITS TO 30830 PROTEINS IN 1152 SPECIES ARCHAE - 207 BACTERIA - 18692 METAZOA - 20758 FUNGI - 6782 PLANTS - 2177 VIRUSES - 523 OTHER EUKARYOTES - 15529 (SOURCE NCBI BLINK) |
AT1G77470 | PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.2408
| Unknown | REPLICATION FACTOR C 36 KDA PUTATIVE |
AT1G78800 | PredictedSynthetic Lethality | FSW = 0.0369
| Unknown | GLYCOSYL TRANSFERASE FAMILY 1 PROTEIN |
AT2G20000 | PredictedSynthetic LethalityCo-expression | FSW = 0.0110
| Unknown | HBT (HOBBIT) BINDING |
AT2G44580 | PredictedAffinity Capture-MS | FSW = 0.1663
| Unknown | PROTEIN BINDING / ZINC ION BINDING |
AT3G25100 | PredictedSynthetic LethalityCo-expression | FSW = 0.1007
| Unknown | CDC45 (CELL DIVISION CYCLE 45) |
AT3G46940 | PredictedSynthetic LethalityCo-expression | FSW = 0.0123
| Unknown | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE FAMILY |
AT5G10400 | PredictedAffinity Capture-MS | FSW = 0.0733
| Unknown | HISTONE H3 |
AT5G20600 | PredictedAffinity Capture-MS | FSW = 0.0100
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN RRNA PROCESSING LOCATED IN PRERIBOSOME SMALL SUBUNIT PRECURSOR EXPRESSED IN 22 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S NUCLEOLAR NOP52 (INTERPROIPR010301) HAS 444 BLAST HITS TO 431 PROTEINS IN 151 SPECIES ARCHAE - 0 BACTERIA - 10 METAZOA - 196 FUNGI - 114 PLANTS - 27 VIRUSES - 0 OTHER EUKARYOTES - 97 (SOURCE NCBI BLINK) |
AT1G05910 | PredictedPhenotypic Enhancement | FSW = 0.0395
| Unknown | CELL DIVISION CYCLE PROTEIN 48-RELATED / CDC48-RELATED |
AT1G79890 | PredictedPhenotypic Enhancement | FSW = 0.1715
| Unknown | HELICASE-RELATED |
AT3G02820 | PredictedPhenotypic Enhancement | FSW = 0.1818
| Unknown | ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN |
AT3G26020 | PredictedPhenotypic Enhancement | FSW = 0.0810
| Unknown | SERINE/THREONINE PROTEIN PHOSPHATASE 2A (PP2A) REGULATORY SUBUNIT B PUTATIVE |
AT3G42660 | PredictedPhenotypic Enhancement | FSW = 0.1793
| Unknown | NUCLEOTIDE BINDING |
AT4G27180 | PredictedPhenotypic Enhancement | FSW = 0.1081
| Unknown | ATK2 (ARABIDOPSIS THALIANA KINESIN 2) MICROTUBULE BINDING / MICROTUBULE MOTOR |
AT4G30870 | PredictedPhenotypic Enhancement | FSW = 0.0757
| Unknown | MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING |
AT4G38630 | PredictedPhenotypic Enhancement | FSW = 0.0752
| Unknown | RPN10 (REGULATORY PARTICLE NON-ATPASE 10) PEPTIDE RECEPTOR |
AT5G10390 | PredictedPhenotypic Enhancement | FSW = 0.0697
| Unknown | HISTONE H3 |
AT5G26680 | PredictedPhenotypic Enhancement | FSW = 0.1646
| Unknown | ENDONUCLEASE PUTATIVE |
AT5G43500 | PredictedPhenotypic Suppression | FSW = 0.1446
| Unknown | ATARP9 (ACTIN-RELATED PROTEIN 9) DNA BINDING / PROTEIN BINDING |
AT5G48120 | PredictedPhenotypic Enhancement | FSW = 0.0885
| Unknown | BINDING |
AT5G49010 | PredictedSynthetic LethalityCo-expression | FSW = 0.0519
| Unknown | SLD5 (SYNTHETIC LETHALITY WITH DPB11-1 5) |
AT5G61460 | PredictedSynthetic Lethality | FSW = 0.0317
| Unknown | MIM (HYPERSENSITIVE TO MMS IRRADIATION AND MMC) ATP BINDING |
AT5G67100 | PredictedSynthetic LethalityCo-expression | FSW = 0.0960
| Unknown | ICU2 (INCURVATA2) DNA-DIRECTED DNA POLYMERASE |
AT1G09200 | PredictedAffinity Capture-MSCo-expression | FSW = 0.0480
| Unknown | HISTONE H3 |
AT4G12600 | PredictedAffinity Capture-MS | FSW = 0.0212
| Unknown | RIBOSOMAL PROTEIN L7AE/L30E/S12E/GADD45 FAMILY PROTEIN |
AT4G26870 | PredictedSynthetic LethalityCo-expression | FSW = 0.0301
| Unknown | ASPARTYL-TRNA SYNTHETASE PUTATIVE / ASPARTATE--TRNA LIGASE PUTATIVE |
AT5G07660 | PredictedSynthetic Lethality | FSW = 0.0258
| Unknown | STRUCTURAL MAINTENANCE OF CHROMOSOMES (SMC) FAMILY PROTEIN |
AT5G42190 | Predictedinteraction prediction | FSW = 0.0083
| Unknown | ASK2 (ARABIDOPSIS SKP1-LIKE 2) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454