Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G20850 - ( ATRAD51 ATP binding / DNA binding / DNA-dependent ATPase/ damaged DNA binding / nucleoside-triphosphatase/ nucleotide binding / protein binding / sequence-specific DNA binding )

196 Proteins interacs with AT5G20850
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT5G01820

Experimental

FSW = 0.0106

Class D:

cytosol (p = 0.67)

ATSR1 (ARABIDOPSIS THALIANA SERINE/THREONINE PROTEIN KINASE 1) ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT5G63310

Experimental

FSW = 0.0058

Class D:

cytosol (p = 0.67)

NDPK2 (NUCLEOSIDE DIPHOSPHATE KINASE 2) ATP BINDING / NUCLEOSIDE DIPHOSPHATE KINASE/ PROTEIN BINDING
AT1G70310

Experimental

FSW = 0.0113

Class D:

cytosol (p = 0.67)

SPDS2 (SPERMIDINE SYNTHASE 2) SPERMIDINE SYNTHASE
AT1G22280

Experimental

FSW = 0.0134

Unknown

PROTEIN PHOSPHATASE 2C PUTATIVE / PP2C PUTATIVE
AT1G09530

Experimental

FSW = 0.0034

Unknown

PIF3 (PHYTOCHROME INTERACTING FACTOR 3) DNA BINDING / PROTEIN BINDING / TRANSCRIPTION FACTOR/ TRANSCRIPTION REGULATOR
AT3G19210

Experimental

two hybrid

one hybrid

two hybrid

FSW = 0.4024

Unknown

ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT5G01630

Experimental

Affinity Capture-Western

coimmunoprecipitation

FSW = 0.0273

Unknown

BRCA2B (BRCA2-LIKE B) PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
AT3G29350

Experimental

FSW = 0.0100

Unknown

AHP2 (HISTIDINE-CONTAINING PHOSPHOTRANSMITTER 2) HISTIDINE PHOSPHOTRANSFER KINASE/ PROTEIN BINDING / SIGNAL TRANSDUCER
AT3G22880

Experimental

Affinity Capture-Western

coimmunoprecipitation

FSW = 0.0328

Class D:

cytosol (p = 0.67)

DMC1 (DISRUPTION OF MEIOTIC CONTROL 1) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING
AT5G57450

Experimental

interaction detection method

FSW = 0.3936

Unknown

XRCC3 ATP BINDING / DAMAGED DNA BINDING / PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
AT5G25350

Experimental

two hybrid

FSW = 0.0280

Unknown

EBF2 (EIN3-BINDING F BOX PROTEIN 2) PROTEIN BINDING
AT5G45010

Experimental

FSW = 0.0245

Unknown

ATDSS1(V) (ARABIDOPSIS DSS1 HOMOLOG ON CHROMOSOME V)
AT3G21340

Experimental

FSW = 0.0101

Unknown

LEUCINE-RICH REPEAT PROTEIN KINASE PUTATIVE
AT3G49470

Experimental

FSW = 0.0215

Unknown

NACA2 (NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-LIKE PROTEIN 2)
AT3G16130

Experimental

FSW = 0.0134

Unknown

ROPGEF13 RHO GUANYL-NUCLEOTIDE EXCHANGE FACTOR
AT2G44540

Experimental

FSW = 0.0042

Unknown

ATGH9B9 (ARABIDOPSIS THALIANA GLYCOSYL HYDROLASE 9B9) CATALYTIC/ HYDROLASE HYDROLYZING O-GLYCOSYL COMPOUNDS
AT1G02990

Experimental

FSW = 0.0201

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS ZINC ION BINDING (TAIRAT3G629001) HAS 5071 BLAST HITS TO 3731 PROTEINS IN 313 SPECIES ARCHAE - 10 BACTERIA - 271 METAZOA - 2187 FUNGI - 266 PLANTS - 194 VIRUSES - 11 OTHER EUKARYOTES - 2132 (SOURCE NCBI BLINK)
AT1G64750

Experimental

FSW = 0.0364

Unknown

ATDSS1(I) (ARABIDOPSIS THALIANA DELETION OF SUV3 SUPRESSOR 1(I))
AT4G29170

Experimental

FSW = 0.0655

Unknown

ATMND1
AT4G17380

Experimental

confocal microscopy

FSW = 0.0163

Unknown

MSH4 (MUTS HOMOLOG 4) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING
AT4G09140

Experimental

confocal microscopy

FSW = 0.0829

Unknown

MLH1 (MUTL-HOMOLOGUE 1) PROTEIN BINDING BRIDGING
AT4G00020

Experimental

two hybrid

Affinity Capture-Western

two hybrid

coimmunoprecipitation

FSW = 0.0368

Unknown

PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
YGL163CExperimental

two hybrid

FSW = 0.0052

Unknown

PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
ETG5888Experimental

two hybrid

FSW = 0.0300

Unknown

PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
RP1-199H16.Experimental

two hybrid

FSW = 0.0201

Unknown

PROTEIN BINDING / SINGLE-STRANDED DNA BINDING
AT4G01100

Predicted

two hybrid

FSW = 0.0021

Unknown

ADNT1 (ADENINE NUCLEOTIDE TRANSPORTER 1) ADP TRANSMEMBRANE TRANSPORTER/ AMP TRANSMEMBRANE TRANSPORTER/ ATP TRANSMEMBRANE TRANSPORTER/ BINDING
AT2G33210

Predicted

Affinity Capture-MS

FSW = 0.0051

Unknown

HSP60-2 (HEAT SHOCK PROTEIN 60-2) ATP BINDING
AT3G04120

Predicted

Affinity Capture-MS

FSW = 0.0372

Unknown

GAPC1 (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE C SUBUNIT 1) GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (PHOSPHORYLATING)/ GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
AT1G56070

Predicted

Affinity Capture-MS

FSW = 0.0349

Unknown

LOS1 COPPER ION BINDING / TRANSLATION ELONGATION FACTOR/ TRANSLATION FACTOR NUCLEIC ACID BINDING
AT3G23990

Predicted

Affinity Capture-MS

FSW = 0.0171

Unknown

HSP60 (HEAT SHOCK PROTEIN 60) ATP BINDING
AT3G22110

Predicted

Phenotypic Enhancement

FSW = 0.0267

Unknown

PAC1 ENDOPEPTIDASE/ PEPTIDASE/ THREONINE-TYPE ENDOPEPTIDASE
AT2G06510

Predicted

Phenotypic Enhancement

Affinity Capture-MS

Affinity Capture-MS

Phenotypic Enhancement

Synthetic Rescue

interaction prediction

FSW = 0.1145

Unknown

RPA1A (REPLICATION PROTEIN A 1A) DNA BINDING / NUCLEIC ACID BINDING
AT1G76490

Predicted

Affinity Capture-MS

FSW = 0.0034

Unknown

HMG1 (HYDROXY METHYLGLUTARYL COA REDUCTASE 1) HYDROXYMETHYLGLUTARYL-COA REDUCTASE
AT3G52140Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0151

Unknown

TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN
AT5G43530

Predicted

synthetic growth defect

Phenotypic Enhancement

synthetic growth defect

Phenotypic Enhancement

FSW = 0.1807

Unknown

SNF2 DOMAIN-CONTAINING PROTEIN / HELICASE DOMAIN-CONTAINING PROTEIN / RING FINGER DOMAIN-CONTAINING PROTEIN
AT1G11870

Predicted

Synthetic Lethality

FSW = 0.0129

Unknown

SRS (SERYL-TRNA SYNTHETASE) SERINE-TRNA LIGASE
AT2G45300

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0478

Unknown

3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE / 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE / EPSP SYNTHASE
AT3G48190

Predicted

Affinity Capture-Western

FSW = 0.0507

Unknown

ATM (ATAXIA-TELANGIECTASIA MUTATED) 1-PHOSPHATIDYLINOSITOL-3-PHOSPHATE 5-KINASE
AT1G12520

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.1803

Unknown

ATCCS (COPPER CHAPERONE FOR SOD1) SUPEROXIDE DISMUTASE/ SUPEROXIDE DISMUTASE COPPER CHAPERONE
AT2G33340

Predicted

Synthetic Rescue

FSW = 0.0097

Unknown

NUCLEOTIDE BINDING / UBIQUITIN-PROTEIN LIGASE
AT4G14970Predicted

in vivo

FSW = 0.0443

Unknown

UNKNOWN PROTEIN
AT2G28190

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.1332

Unknown

CSD2 (COPPER/ZINC SUPEROXIDE DISMUTASE 2) SUPEROXIDE DISMUTASE
AT3G11630

Predicted

Synthetic Lethality

synthetic growth defect

Synthetic Lethality

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.1342

Unknown

2-CYS PEROXIREDOXIN CHLOROPLAST (BAS1)
AT3G10050

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0403

Unknown

OMR1 (L-O-METHYLTHREONINE RESISTANT 1) L-THREONINE AMMONIA-LYASE
AT1G48860

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0090

Unknown

3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE PUTATIVE / 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE PUTATIVE / EPSP SYNTHASE PUTATIVE
AT5G63110

Predicted

Phenotypic Enhancement

FSW = 0.0632

Unknown

HDA6 (HISTONE DEACETYLASE 6) HISTONE DEACETYLASE
ATCG00830Predicted

synthetic growth defect

FSW = 0.0160

Unknown

ENCODES A CHLOROPLAST RIBOSOMAL PROTEIN L2 A CONSTITUENT OF THE LARGE SUBUNIT OF THE RIBOSOMAL COMPLEX
AT5G56030

Predicted

Affinity Capture-MS

FSW = 0.0215

Unknown

HSP81-2 (HEAT SHOCK PROTEIN 81-2) ATP BINDING
AT1G75950

Predicted

two hybrid

FSW = 0.0058

Unknown

SKP1 (S PHASE KINASE-ASSOCIATED PROTEIN 1) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT1G07670

Predicted

synthetic growth defect

FSW = 0.0338

Unknown

CALCIUM-TRANSPORTING ATPASE
AT5G52640

Predicted

Affinity Capture-MS

FSW = 0.0282

Unknown

ATHSP901 (HEAT SHOCK PROTEIN 901) ATP BINDING / UNFOLDED PROTEIN BINDING
AT3G18524

Predicted

Phenotypic Suppression

FSW = 0.1535

Unknown

MSH2 (MUTS HOMOLOG 2) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT4G17270

Predicted

Affinity Capture-MS

FSW = 0.0159

Unknown

MO25 FAMILY PROTEIN
AT3G17750

Predicted

two hybrid

FSW = 0.0291

Unknown

PROTEIN KINASE FAMILY PROTEIN
AT1G16970

Predicted

Synthetic Rescue

Synthetic Lethality

FSW = 0.0857

Unknown

KU70 (ARABIDOPSIS THALIANA KU70 HOMOLOG) DOUBLE-STRANDED DNA BINDING / PROTEIN BINDING
AT4G39850

Predicted

two hybrid

two hybrid

FSW = 0.0050

Unknown

PXA1 (PEROXISOMAL ABC TRANSPORTER 1) ATPASE COUPLED TO TRANSMEMBRANE MOVEMENT OF SUBSTANCES
AT1G48050

Predicted

Phenotypic Enhancement

FSW = 0.0273

Unknown

KU80 DOUBLE-STRANDED DNA BINDING / PROTEIN BINDING
AT5G57015

Predicted

two hybrid

interaction prediction

FSW = 0.0050

Unknown

CKL12 (CASEIN KINASE I-LIKE 12) ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT4G26720

Predicted

Synthetic Lethality

FSW = 0.1091

Unknown

PPX1 (PROTEIN PHOSPHATASE X 1) PROTEIN SERINE/THREONINE PHOSPHATASE
AT2G15240

Predicted

interologs mapping

FSW = 0.0500

Unknown

UNC-50 FAMILY PROTEIN
AT1G03930

Predicted

two hybrid

FSW = 0.0011

Unknown

ADK1 (DUAL SPECIFICITY KINASE 1) KINASE/ PROTEIN SERINE/THREONINE/TYROSINE KINASE
AT5G67270

Predicted

synthetic growth defect

synthetic growth defect

FSW = 0.1306

Unknown

ATEB1C (MICROTUBULE END BINDING PROTEIN 1) MICROTUBULE BINDING
AT1G13330

Predicted

interologs mapping

FSW = 0.0546

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 11 PLANT STRUCTURES EXPRESSED DURING 6 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S TAT BINDING PROTEIN 1-INTERACTING (INTERPROIPR010776) HAS 2425 BLAST HITS TO 2142 PROTEINS IN 283 SPECIES ARCHAE - 50 BACTERIA - 240 METAZOA - 929 FUNGI - 179 PLANTS - 47 VIRUSES - 23 OTHER EUKARYOTES - 957 (SOURCE NCBI BLINK)
AT2G43810

Predicted

synthetic growth defect

FSW = 0.0886

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN F PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE / SM PROTEIN F PUTATIVE
AT5G64630

Predicted

Phenotypic Enhancement

FSW = 0.0825

Unknown

FAS2 (FASCIATA 2) NUCLEOTIDE BINDING / PROTEIN BINDING
AT1G19120

Predicted

synthetic growth defect

FSW = 0.1272

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE
AT2G03870

Predicted

Synthetic Lethality

FSW = 0.1125

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE
AT5G22750

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.2323

Unknown

RAD5 ATP BINDING / ATP-DEPENDENT HELICASE/ DNA BINDING / HELICASE/ HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING / PROTEIN BINDING / ZINC ION BINDING
AT2G26150

Predicted

synthetic growth defect

FSW = 0.0864

Unknown

ATHSFA2 DNA BINDING / TRANSCRIPTION FACTOR
AT1G04510

Predicted

Synthetic Rescue

FSW = 0.0094

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G06720

Predicted

interaction prediction

FSW = 0.0141

Unknown

IMPA-1 (IMPORTIN ALPHA ISOFORM 1) BINDING / PROTEIN TRANSPORTER
AT2G24490

Predicted

Phenotypic Enhancement

two hybrid

FSW = 0.0954

Unknown

RPA2 (REPLICON PROTEIN A2) PROTEIN BINDING
AT3G02920

Predicted

two hybrid

FSW = 0.0203

Unknown

REPLICATION PROTEIN-RELATED
AT1G51060

Predicted

Phenotypic Enhancement

FSW = 0.0187

Unknown

HTA10 DNA BINDING
AT5G45400

Predicted

in vitro

in vivo

FSW = 0.0296

Unknown

REPLICATION PROTEIN PUTATIVE
AT5G61000

Predicted

in vitro

in vivo

FSW = 0.0291

Unknown

REPLICATION PROTEIN PUTATIVE
AT1G07370

Predicted

Phenotypic Enhancement

FSW = 0.2287

Unknown

PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING
AT1G65470

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1802

Unknown

FAS1 (FASCIATA 1) HISTONE BINDING
AT2G38560

Predicted

Phenotypic Enhancement

FSW = 0.0802

Unknown

TFIIS (TRANSCRIPT ELONGATION FACTOR IIS) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION ELONGATION FACTOR/ TRANSCRIPTION FACTOR
AT2G44950

Predicted

synthetic growth defect

FSW = 0.1591

Unknown

HUB1 (HISTONE MONO-UBIQUITINATION 1) PROTEIN BINDING / PROTEIN HOMODIMERIZATION/ UBIQUITIN-PROTEIN LIGASE/ ZINC ION BINDING
AT5G48030

Predicted

in vivo

in vitro

FSW = 0.0053

Unknown

GFA2 (GAMETOPHYTIC FACTOR 2) HEAT SHOCK PROTEIN BINDING / UNFOLDED PROTEIN BINDING
AT1G35940Predicted

synthetic growth defect

FSW = 0.1722

Unknown

GFA2 (GAMETOPHYTIC FACTOR 2) HEAT SHOCK PROTEIN BINDING / UNFOLDED PROTEIN BINDING
AT1G61570

Predicted

Affinity Capture-MS

FSW = 0.0318

Unknown

TIM13 (TRANSLOCASE OF THE INNER MITOCHONDRIAL MEMBRANE 13) P-P-BOND-HYDROLYSIS-DRIVEN PROTEIN TRANSMEMBRANE TRANSPORTER
AT5G26710

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0286

Unknown

GLUTAMATE-TRNA LIGASE PUTATIVE / GLUTAMYL-TRNA SYNTHETASE PUTATUVE / GLURS PUTATIVE
AT1G10130

Predicted

synthetic growth defect

FSW = 0.0313

Unknown

ECA3 (ENDOPLASMIC RETICULUM-TYPE CALCIUM-TRANSPORTING ATPASE 3) CALCIUM-TRANSPORTING ATPASE/ CALMODULIN BINDING / MANGANESE-TRANSPORTING ATPASE/ PEROXIDASE
AT3G08730

Predicted

two hybrid

FSW = 0.0017

Unknown

PK1 (PROTEIN-SERINE KINASE 1) KINASE/ PROTEIN BINDING / PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT3G47690

Predicted

synthetic growth defect

synthetic growth defect

FSW = 0.0965

Unknown

ATEB1A MICROTUBULE BINDING
AT2G31970

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.4144

Unknown

RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING
AT2G45280

Predicted

Colocalization

Phylogenetic profile method

Co-expression

FSW = 0.0476

Unknown

ATRAD51C ATP BINDING / DAMAGED DNA BINDING / PROTEIN BINDING / RECOMBINASE/ SINGLE-STRANDED DNA BINDING
AT5G40820

Predicted

Phenotypic Enhancement

synthetic growth defect

FSW = 0.2092

Unknown

ATRAD3 BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR / PROTEIN SERINE/THREONINE KINASE
AT1G07745

Predicted

Colocalization

FSW = 0.0780

Unknown

RAD51D (ARABIDOPSIS HOMOLOG OF RAD51 D) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE
AT2G28560

Predicted

Colocalization

FSW = 0.0354

Unknown

RAD51B RECOMBINASE
AT5G58290

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

Gene neighbors method

Co-expression

FSW = 0.0274

Unknown

RPT3 (REGULATORY PARTICLE TRIPLE-A ATPASE 3) ATPASE
AT5G38470

Predicted

Affinity Capture-MS

FSW = 0.0602

Unknown

DNA REPAIR PROTEIN RAD23 PUTATIVE
AT1G08830

Predicted

Synthetic Lethality

FSW = 0.1194

Unknown

CSD1 (COPPER/ZINC SUPEROXIDE DISMUTASE 1) SUPEROXIDE DISMUTASE
AT5G41150

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1327

Unknown

UVH1 (ULTRAVIOLET HYPERSENSITIVE 1) SINGLE-STRANDED DNA SPECIFIC ENDODEOXYRIBONUCLEASE
AT5G66130

Predicted

interologs mapping

interologs mapping

Synthetic Lethality

Phenotypic Suppression

synthetic growth defect

FSW = 0.2434

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT1G16190

Predicted

Affinity Capture-MS

FSW = 0.0284

Unknown

DNA REPAIR PROTEIN RAD23 PUTATIVE
AT5G64520

Predicted

Colocalization

FSW = 0.0270

Unknown

XRCC2
AT4G21710

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0296

Unknown

NRPB2 DNA BINDING / DNA-DIRECTED RNA POLYMERASE
AT5G63960

Predicted

Synthetic Lethality

FSW = 0.0826

Unknown

EMB2780 (EMBRYO DEFECTIVE 2780) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING
AT3G28030

Predicted

Phenotypic Suppression

FSW = 0.0808

Unknown

UVH3 (ULTRAVIOLET HYPERSENSITIVE 3) DNA BINDING / CATALYTIC/ ENDONUCLEASE/ NUCLEASE/ SINGLE-STRANDED DNA BINDING
AT3G48470

Predicted

Phenotypic Enhancement

FSW = 0.0074

Unknown

EMB2423 (EMBRYO DEFECTIVE 2423)
AT4G20920

Predicted

two hybrid

FSW = 0.0201

Unknown

DOUBLE-STRANDED RNA BINDING
AT1G26830

Predicted

two hybrid

two hybrid

FSW = 0.0051

Unknown

ATCUL3 (ARABIDOPSIS THALIANA CULLIN 3) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT1G27880

Predicted

two hybrid

two hybrid

FSW = 0.0054

Unknown

ATP-DEPENDENT DNA HELICASE PUTATIVE
AT1G53710

Predicted

two hybrid

two hybrid

FSW = 0.0103

Unknown

HYDROLASE/ PROTEIN SERINE/THREONINE PHOSPHATASE
AT1G67320

Predicted

two hybrid

two hybrid

FSW = 0.0524

Unknown

DNA PRIMASE LARGE SUBUNIT FAMILY
AT1G77720

Predicted

two hybrid

FSW = 0.0169

Unknown

PROTEIN KINASE FAMILY PROTEIN
AT1G79000

Predicted

two hybrid

two hybrid

FSW = 0.0080

Unknown

HAC1 (HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 1) H3/H4 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE/ TRANSCRIPTION COFACTOR
AT2G01120

Predicted

two hybrid

FSW = 0.0118

Unknown

ORC4 (ORIGIN RECOGNITION COMPLEX SUBUNIT 4) PROTEIN BINDING
AT2G27960

Predicted

two hybrid

two hybrid

FSW = 0.0178

Unknown

CKS1 (CYCLIN-DEPENDENT KINASE-SUBUNIT 1) CYCLIN-DEPENDENT PROTEIN KINASE/ PROTEIN BINDING
AT2G27970

Predicted

two hybrid

Phenotypic Enhancement

FSW = 0.0500

Unknown

CKS2 (CDK-SUBUNIT 2) CYCLIN-DEPENDENT PROTEIN KINASE/ CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT3G12980

Predicted

two hybrid

FSW = 0.0078

Unknown

HAC5 H3/H4 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE
AT3G54180

Predicted

two hybrid

FSW = 0.0227

Unknown

CDKB11 (CYCLIN-DEPENDENT KINASE B11) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING
AT4G24740

Predicted

two hybrid

FSW = 0.0267

Unknown

AFC2 (ARABIDOPSIS FUS3-COMPLEMENTING GENE 2) KINASE/ PROTEIN KINASE
AT4G32660

Predicted

two hybrid

FSW = 0.0329

Unknown

AME3 ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT5G27620

Predicted

two hybrid

two hybrid

FSW = 0.0171

Unknown

CYCH1 (CYCLIN H1) CYCLIN-DEPENDENT PROTEIN KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT5G42190

Predicted

two hybrid

FSW = 0.0121

Unknown

ASK2 (ARABIDOPSIS SKP1-LIKE 2) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT5G47240

Predicted

two hybrid

two hybrid

FSW = 0.0192

Unknown

ATNUDT8 (ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 8) HYDROLASE
AT5G47650

Predicted

two hybrid

FSW = 0.0187

Unknown

ATNUDT2 (ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 2) ADP-RIBOSE DIPHOSPHATASE/ NAD OR NADH BINDING / HYDROLASE
AT5G49110

Predicted

two hybrid

two hybrid

FSW = 0.0054

Unknown

UNKNOWN PROTEIN
AT1G10930

Predicted

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

synthetic growth defect

Synthetic Rescue

Phenotypic Suppression

Phenotypic Suppression

Synthetic Rescue

Phenotypic Suppression

Phenotypic Enhancement

Affinity Capture-Western

two hybrid

in vivo

in vitro

far western blotting

Phenotypic Enhancement

Phenotypic Suppression

FSW = 0.2562

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT1G71350

Predicted

Affinity Capture-MS

FSW = 0.0138

Unknown

EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 FAMILY PROTEIN
AT3G05740

Predicted

Affinity Capture-Western

two hybrid

in vivo

in vitro

far western blotting

FSW = 0.1340

Unknown

RECQI1 (ARABIDOPSIS RECQ HELICASE L1) ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT3G57870

Predicted

interaction prediction

two hybrid

two hybrid

two hybrid

in vivo

Synthetic Lethality

FSW = 0.0546

Unknown

SCE1 (SUMO CONJUGATION ENZYME 1) SUMO LIGASE
AT5G18940

Predicted

Affinity Capture-MS

FSW = 0.0265

Unknown

MO25 FAMILY PROTEIN
AT1G04020

Predicted

synthetic growth defect

synthetic growth defect

Affinity Capture-MS

Affinity Capture-Western

Phenotypic Enhancement

FSW = 0.2985

Unknown

BARD1 (BREAST CANCER ASSOCIATED RING 1) DNA BINDING / TRANSCRIPTION COACTIVATOR
AT1G80210

Predicted

Affinity Capture-MS

Affinity Capture-Western

Co-purification

FSW = 0.0398

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN ENDOMEMBRANE SYSTEM EXPRESSED IN MALE GAMETOPHYTE EXPRESSED DURING L MATURE POLLEN STAGE M GERMINATED POLLEN STAGE CONTAINS INTERPRO DOMAIN/S MOV34/MPN/PAD-1 (INTERPROIPR000555) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS MOV34 FAMILY PROTEIN (TAIRAT3G068202) HAS 785 BLAST HITS TO 706 PROTEINS IN 167 SPECIES ARCHAE - 0 BACTERIA - 3 METAZOA - 423 FUNGI - 147 PLANTS - 120 VIRUSES - 0 OTHER EUKARYOTES - 92 (SOURCE NCBI BLINK)
AT3G06820

Predicted

Affinity Capture-MS

Affinity Capture-Western

Co-purification

FSW = 0.0257

Unknown

MOV34 FAMILY PROTEIN
AT4G27230

Predicted

Colocalization

FSW = 0.0373

Unknown

HTA2 (HISTONE H2A) DNA BINDING
AT5G02560

Predicted

Colocalization

FSW = 0.0069

Unknown

HTA12 DNA BINDING
AT5G42470

Predicted

Affinity Capture-MS

Affinity Capture-Western

Co-purification

FSW = 0.0271

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 24 PLANT STRUCTURES EXPRESSED DURING 14 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S BRAIN AND REPRODUCTIVE ORGAN-EXPRESSED (INTERPROIPR010358) HAS 125 BLAST HITS TO 120 PROTEINS IN 32 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 108 FUNGI - 0 PLANTS - 14 VIRUSES - 0 OTHER EUKARYOTES - 3 (SOURCE NCBI BLINK)
AT5G48700

Predicted

two hybrid

in vivo

in vivo

two hybrid

FSW = 0.0114

Unknown

UBIQUITIN-RELATED
AT1G04730Predicted

Synthetic Lethality

synthetic growth defect

interaction prediction

FSW = 0.2787

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT1G24290

Predicted

Dosage Growth Defect

interologs mapping

FSW = 0.1194

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT1G29940Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0186

Unknown

NRPA2 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ RIBONUCLEOSIDE BINDING
AT1G49520

Predicted

two hybrid

FSW = 0.0057

Unknown

SWIB COMPLEX BAF60B DOMAIN-CONTAINING PROTEIN
AT1G60490

Predicted

synthetic growth defect

FSW = 0.0929

Unknown

ATVPS34 1-PHOSPHATIDYLINOSITOL-3-KINASE/ BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR
AT1G64550

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0345

Unknown

ATGCN3 TRANSPORTER
AT1G66740

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.2324

Unknown

SGA2
AT1G67190

Predicted

synthetic growth defect

FSW = 0.1738

Unknown

F-BOX FAMILY PROTEIN
AT1G67500

Predicted

synthetic growth defect

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1211

Unknown

ATREV3 (ARABIDOPSIS THALIANA RECOVERY PROTEIN 3) DNA BINDING / DNA-DIRECTED DNA POLYMERASE
AT1G80410

Predicted

synthetic growth defect

FSW = 0.1182

Unknown

EMB2753 (EMBRYO DEFECTIVE 2753) BINDING
AT2G02760

Predicted

Phenotypic Enhancement

synthetic growth defect

Phenotypic Enhancement

FSW = 0.1890

Unknown

ATUBC2 (UBIQUITING-CONJUGATING ENZYME 2) UBIQUITIN-PROTEIN LIGASE
AT2G04660

Predicted

two hybrid

interaction prediction

FSW = 0.0068

Unknown

APC2 UBIQUITIN PROTEIN LIGASE BINDING / UBIQUITIN-PROTEIN LIGASE
AT2G22480

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0113

Unknown

PFK5 (PHOSPHOFRUCTOKINASE 5) 6-PHOSPHOFRUCTOKINASE
AT2G25100

Predicted

synthetic growth defect

FSW = 0.0390

Unknown

RIBONUCLEASE HII FAMILY PROTEIN
AT2G39770

Predicted

Affinity Capture-MS

FSW = 0.0553

Unknown

CYT1 (CYTOKINESIS DEFECTIVE 1) MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE/ NUCLEOTIDYLTRANSFERASE
AT2G44580

Predicted

Synthetic Lethality

synthetic growth defect

interaction prediction

FSW = 0.2671

Unknown

PROTEIN BINDING / ZINC ION BINDING
AT2G45500

Predicted

interaction prediction

two hybrid

FSW = 0.0248

Unknown

ATP BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT3G02820

Predicted

synthetic growth defect

FSW = 0.2398

Unknown

ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN
AT3G12400

Predicted

synthetic growth defect

FSW = 0.1341

Unknown

ELC UBIQUITIN BINDING
AT3G24090

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0272

Unknown

GLUTAMINE-FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)/ SUGAR BINDING / TRANSAMINASE
AT3G42660

Predicted

Synthetic Lethality

synthetic growth defect

Synthetic Lethality

interaction prediction

FSW = 0.3232

Unknown

NUCLEOTIDE BINDING
AT3G58560

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.1465

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT4G11920

Predicted

synthetic growth defect

FSW = 0.1051

Unknown

CCS52A2 SIGNAL TRANSDUCER
AT4G25120Predicted

two hybrid

two hybrid

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Lethality

synthetic growth defect

Phenotypic Enhancement

Affinity Capture-Western

Affinity Capture-Western

synthetic growth defect

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Phenotypic Enhancement

Phenotypic Suppression

FSW = 0.2996

Unknown

ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING / HYDROLASE
AT4G27640

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0063

Unknown

IMPORTIN BETA-2 SUBUNIT FAMILY PROTEIN
AT4G29380

Predicted

synthetic growth defect

FSW = 0.0506

Unknown

PROTEIN KINASE FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT4G30870

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.1691

Unknown

MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING
AT4G38630

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.1301

Unknown

RPN10 (REGULATORY PARTICLE NON-ATPASE 10) PEPTIDE RECEPTOR
AT5G10270

Predicted

Synthetic Lethality

FSW = 0.1115

Unknown

CDKC1 (CYCLIN-DEPENDENT KINASE C1) KINASE
AT5G10960

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.1564

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT5G13780

Predicted

synthetic growth defect

FSW = 0.1461

Unknown

GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE
AT1G08840Predicted

Synthetic Rescue

Synthetic Lethality

FSW = 0.1371

Unknown

EMB2411 (EMBRYO DEFECTIVE 2411) ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING
AT1G63160

Predicted

Phenotypic Enhancement

FSW = 0.0916

Unknown

REPLICATION FACTOR C 40 KDA PUTATIVE
AT2G45700

Predicted

Phenotypic Enhancement

FSW = 0.0480

Unknown

STERILE ALPHA MOTIF (SAM) DOMAIN-CONTAINING PROTEIN
AT3G06910

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.0552

Unknown

ULP1A (UB-LIKE PROTEASE 1A) SUMO-SPECIFIC PROTEASE/ CYSTEINE-TYPE PEPTIDASE
AT3G18520

Predicted

Phenotypic Enhancement

FSW = 0.0369

Unknown

HDA15 HISTONE DEACETYLASE
AT3G18860

Predicted

Phenotypic Enhancement

FSW = 0.1155

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G22142

Predicted

Affinity Capture-MS

FSW = 0.0260

Unknown

STRUCTURAL CONSTITUENT OF CELL WALL
AT4G25540

Predicted

Phenotypic Suppression

FSW = 0.0537

Unknown

MSH3 (ARABIDOPSIS HOMOLOG OF DNA MISMATCH REPAIR PROTEIN MSH3) DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT5G09740

Predicted

synthetic growth defect

FSW = 0.0899

Unknown

HAM2 (HISTONE ACETYLTRANSFERASE OF THE MYST FAMILY 2) H3/H4 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE/ NUCLEIC ACID BINDING / ZINC ION BINDING
AT5G26680

Predicted

interaction prediction

Synthetic Lethality

Synthetic Lethality

Synthetic Lethality

Synthetic Lethality

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.3447

Unknown

ENDONUCLEASE PUTATIVE
AT5G41880

Predicted

Phenotypic Enhancement

FSW = 0.0972

Unknown

POLA3 DNA PRIMASE
AT5G44750

Predicted

Phenotypic Enhancement

synthetic growth defect

FSW = 0.0308

Unknown

REV1 DNA-DIRECTED DNA POLYMERASE
AT5G59440

Predicted

Phenotypic Enhancement

FSW = 0.0245

Unknown

ZEU1 (ZEUS1) ATP BINDING / THYMIDYLATE KINASE
AT5G63920

Predicted

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

Synthetic Rescue

FSW = 0.1516

Unknown

DNA TOPOISOMERASE III ALPHA PUTATIVE
AT5G27740

Predicted

Phenotypic Enhancement

FSW = 0.1241

Unknown

EMB2775 (EMBRYO DEFECTIVE 2775) DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT5G27970Predicted

synthetic growth defect

FSW = 0.1133

Unknown

BINDING
AT3G05480

Predicted

synthetic growth defect

interologs mapping

FSW = 0.0384

Unknown

RAD9
AT4G19130

Predicted

two hybrid

FSW = 0.0201

Unknown

DNA BINDING / NUCLEIC ACID BINDING / ZINC ION BINDING
AT5G02820

Predicted

Colocalization

FSW = 0.0437

Unknown

RHL2 (ROOT HAIRLESS 2) ATP BINDING / DNA BINDING / DNA TOPOISOMERASE (ATP-HYDROLYZING)/ IDENTICAL PROTEIN BINDING / PROTEIN BINDING
AT5G67100

Predicted

Phenotypic Suppression

FSW = 0.0999

Unknown

ICU2 (INCURVATA2) DNA-DIRECTED DNA POLYMERASE
AT3G21350

Predicted

Affinity Capture-MS

FSW = 0.0059

Unknown

RNA POLYMERASE TRANSCRIPTIONAL REGULATION MEDIATOR-RELATED
AT3G26680

Predicted

Phenotypic Enhancement

FSW = 0.0506

Unknown

SNM1 (SENSITIVE TO NITROGEN MUSTARD 1)
AT1G55255Predicted

synthetic growth defect

FSW = 0.1089

Unknown

SNM1 (SENSITIVE TO NITROGEN MUSTARD 1)
AT5G40490

Predicted

synthetic growth defect

FSW = 0.0942

Unknown

RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN
AT2G23420

Predicted

synthetic growth defect

FSW = 0.1119

Unknown

NAPRT2 (NICOTINATE PHOSPHORIBOSYLTRANSFERASE 2) NICOTINATE PHOSPHORIBOSYLTRANSFERASE
AT1G14400

Predicted

synthetic growth defect

FSW = 0.1819

Unknown

UBC1 (UBIQUITIN CARRIER PROTEIN 1) UBIQUITIN-PROTEIN LIGASE
AT2G44065

Predicted

synthetic growth defect

FSW = 0.0321

Unknown

RIBOSOMAL PROTEIN L2 FAMILY PROTEIN
AT3G07120

Predicted

synthetic growth defect

FSW = 0.1371

Unknown

ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN
AT1G15920

Predicted

synthetic growth defect

Synthetic Lethality

FSW = 0.1540

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT1G02690

Predicted

two hybrid

FSW = 0.0152

Unknown

IMPA-6 (IMPORTIN ALPHA ISOFORM 6) BINDING / PROTEIN TRANSPORTER
AT4G35450

Predicted

Gene fusion method

FSW = 0.0049

Unknown

AKR2 (ANKYRIN REPEAT-CONTAINING PROTEIN 2) PROTEIN BINDING

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

Learn more

How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454