Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G41150 - ( UVH1 (ULTRAVIOLET HYPERSENSITIVE 1) single-stranded DNA specific endodeoxyribonuclease )

76 Proteins interacs with AT5G41150
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G56070

Predicted

Affinity Capture-MS

FSW = 0.0169

Unknown

LOS1 COPPER ION BINDING / TRANSLATION ELONGATION FACTOR/ TRANSLATION FACTOR NUCLEIC ACID BINDING
AT1G64790Predicted

Phenotypic Enhancement

FSW = 0.0130

Unknown

BINDING
AT5G55400

Predicted

Affinity Capture-MS

FSW = 0.0339

Unknown

FIMBRIN-LIKE PROTEIN PUTATIVE
AT2G06510

Predicted

Synthetic Rescue

Phenotypic Enhancement

Phenotypic Enhancement

interaction prediction

FSW = 0.1287

Unknown

RPA1A (REPLICATION PROTEIN A 1A) DNA BINDING / NUCLEIC ACID BINDING
AT5G43530

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.2197

Unknown

SNF2 DOMAIN-CONTAINING PROTEIN / HELICASE DOMAIN-CONTAINING PROTEIN / RING FINGER DOMAIN-CONTAINING PROTEIN
AT5G40610

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0156

Unknown

GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD+) / GPDH
AT1G71820

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0051

Unknown

SEC6
AT3G18524

Predicted

two hybrid

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

interaction prediction

FSW = 0.2635

Unknown

MSH2 (MUTS HOMOLOG 2) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT1G16970

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1624

Unknown

KU70 (ARABIDOPSIS THALIANA KU70 HOMOLOG) DOUBLE-STRANDED DNA BINDING / PROTEIN BINDING
AT1G21700

Predicted

Phenotypic Enhancement

FSW = 0.0322

Unknown

ATSWI3C (SWITCH/SUCROSE NONFERMENTING 3C) DNA BINDING
AT4G02070

Predicted

Phenotypic Enhancement

FSW = 0.2002

Unknown

MSH6 (MUTS HOMOLOG 6) DAMAGED DNA BINDING
AT3G12810

Predicted

interaction prediction

FSW = 0.0423

Unknown

PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT1G75230

Predicted

Phenotypic Enhancement

FSW = 0.1196

Unknown

HHH-GPD BASE EXCISION DNA REPAIR FAMILY PROTEIN
AT5G37720

Predicted

Affinity Capture-MS

FSW = 0.0056

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT5G64630

Predicted

Phenotypic Enhancement

FSW = 0.0875

Unknown

FAS2 (FASCIATA 2) NUCLEOTIDE BINDING / PROTEIN BINDING
AT5G09860

Predicted

Synthetic Rescue

FSW = 0.0519

Unknown

NUCLEAR MATRIX PROTEIN-RELATED
AT1G02740

Predicted

Phenotypic Enhancement

FSW = 0.0304

Unknown

CHROMATIN BINDING
AT5G22750

Predicted

Phenotypic Enhancement

FSW = 0.1460

Unknown

RAD5 ATP BINDING / ATP-DEPENDENT HELICASE/ DNA BINDING / HELICASE/ HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING / PROTEIN BINDING / ZINC ION BINDING
AT1G07370

Predicted

Phenotypic Suppression

FSW = 0.2587

Unknown

PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING
AT1G65470

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1488

Unknown

FAS1 (FASCIATA 1) HISTONE BINDING
AT3G19210

Predicted

Phenotypic Enhancement

FSW = 0.1473

Unknown

ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT2G37470

Predicted

Phenotypic Enhancement

FSW = 0.0111

Unknown

HISTONE H2B PUTATIVE
AT5G41360

Predicted

Phenotypic Enhancement

FSW = 0.0180

Unknown

XPB2 ATP BINDING / ATP-DEPENDENT DNA HELICASE/ ATP-DEPENDENT HELICASE/ DNA BINDING / HELICASE/ HYDROLASE/ NUCLEIC ACID BINDING
AT1G22660

Predicted

interaction prediction

FSW = 0.0289

Unknown

TRNA-NUCLEOTIDYLTRANSFERASE PUTATIVE / TRNA ADENYLYLTRANSFERASE PUTATIVE
AT3G18480

Predicted

interaction prediction

FSW = 0.0058

Unknown

ATCASP (ARABIDOPSIS THALIANA CCAAT-DISPLACEMENT PROTEIN ALTERNATIVELY SPLICED PRODUCT)
AT2G04750

Predicted

Affinity Capture-MS

FSW = 0.0339

Unknown

FIMBRIN-LIKE PROTEIN PUTATIVE
AT1G18260

Predicted

interaction prediction

FSW = 0.0084

Unknown

SUPPRESSOR OF LIN-12-LIKE PROTEIN-RELATED / SEL-1 PROTEIN-RELATED
AT2G31970

Predicted

Phenotypic Enhancement

FSW = 0.2669

Unknown

RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING
AT5G66130

Predicted

Synthetic Rescue

FSW = 0.1651

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT2G30920

Predicted

Synthetic Rescue

synthetic growth defect

FSW = 0.0145

Unknown

ATCOQ3 (ARABDIOPSIS THALIANA COENZYME Q 3) HEXAPRENYLDIHYDROXYBENZOATE METHYLTRANSFERASE/ POLYPRENYLDIHYDROXYBENZOATE METHYLTRANSFERASE
AT3G25980

Predicted

synthetic growth defect

FSW = 0.0155

Unknown

MITOTIC SPINDLE CHECKPOINT PROTEIN PUTATIVE (MAD2)
AT5G40820

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.1222

Unknown

ATRAD3 BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR / PROTEIN SERINE/THREONINE KINASE
AT5G63960

Predicted

Phenotypic Suppression

FSW = 0.1308

Unknown

EMB2780 (EMBRYO DEFECTIVE 2780) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING
AT3G05210

Predicted

two hybrid

two hybrid

Reconstituted Complex

Reconstituted Complex

Reconstituted Complex

Reconstituted Complex

interologs mapping

co-fractionation

Co-fractionation

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-Western

Reconstituted Complex

two hybrid

Reconstituted Complex

Affinity Capture-Western

in vitro

in vivo

two hybrid

two hybrid

in vivo

in vitro

Affinity Capture-Western

Reconstituted Complex

co-fractionation

Co-fractionation

interologs mapping

Affinity Capture-MS

interologs mapping

interaction prediction

FSW = 0.1996

Unknown

ERCC1 5-FLAP ENDONUCLEASE
AT5G54260

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.2472

Unknown

MRE11 (MEIOTIC RECOMBINATION 11) ENDONUCLEASE/ EXONUCLEASE/ HYDROLASE/ MANGANESE ION BINDING / PROTEIN SERINE/THREONINE PHOSPHATASE
AT5G20850

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.1327

Unknown

ATRAD51 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING / SEQUENCE-SPECIFIC DNA BINDING
AT1G04020

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

synthetic growth defect

Phenotypic Enhancement

FSW = 0.1956

Unknown

BARD1 (BREAST CANCER ASSOCIATED RING 1) DNA BINDING / TRANSCRIPTION COACTIVATOR
AT1G10930

Predicted

synthetic growth defect

Phenotypic Enhancement

Phenotypic Suppression

FSW = 0.1843

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT1G13180

Predicted

Affinity Capture-MS

FSW = 0.0048

Unknown

DIS1 (DISTORTED TRICHOMES 1) ATP BINDING / ACTIN BINDING / PROTEIN BINDING / STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT1G16800

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0196

Unknown

TRNA-SPLICING ENDONUCLEASE POSITIVE EFFECTOR-RELATED
AT1G18090

Predicted

Phenotypic Enhancement

FSW = 0.2526

Unknown

EXONUCLEASE PUTATIVE
AT1G23260

Predicted

Phenotypic Enhancement

FSW = 0.0958

Unknown

MMZ1 (MMS ZWEI HOMOLOGUE 1) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT1G49980

Predicted

Phenotypic Enhancement

FSW = 0.1832

Unknown

DNA-DIRECTED DNA POLYMERASE/ DAMAGED DNA BINDING
AT1G67500

Predicted

Synthetic Rescue

Synthetic Rescue

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.3225

Unknown

ATREV3 (ARABIDOPSIS THALIANA RECOVERY PROTEIN 3) DNA BINDING / DNA-DIRECTED DNA POLYMERASE
AT2G02760

Predicted

Phenotypic Enhancement

synthetic growth defect

FSW = 0.0965

Unknown

ATUBC2 (UBIQUITING-CONJUGATING ENZYME 2) UBIQUITIN-PROTEIN LIGASE
AT2G40430

Predicted

Affinity Capture-MS

FSW = 0.0051

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 22 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S TUMOR SUPPRESSOR PROTEIN GLTSCR2 (INTERPROIPR011211) P60-LIKE (INTERPROIPR011687) HAS 601 BLAST HITS TO 544 PROTEINS IN 148 SPECIES ARCHAE - 0 BACTERIA - 22 METAZOA - 201 FUNGI - 103 PLANTS - 32 VIRUSES - 0 OTHER EUKARYOTES - 243 (SOURCE NCBI BLINK)
AT3G18630

Predicted

Synthetic Rescue

Synthetic Rescue

FSW = 0.0469

Unknown

URACIL DNA GLYCOSYLASE FAMILY PROTEIN
AT3G18860

Predicted

Phenotypic Enhancement

FSW = 0.1003

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G46940

Predicted

interologs mapping

FSW = 0.0508

Unknown

DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE FAMILY
AT4G01860

Predicted

Affinity Capture-MS

FSW = 0.0156

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT4G02460

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.2088

Unknown

PMS1 (POSTMEIOTIC SEGREGATION 1) ATP BINDING / MISMATCHED DNA BINDING
AT4G05320

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0091

Unknown

UBQ10 (POLYUBIQUITIN 10) PROTEIN BINDING
AT4G07410

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0049

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT4G22140

Predicted

Phenotypic Suppression

FSW = 0.0547

Unknown

DNA BINDING / PROTEIN BINDING / ZINC ION BINDING
AT4G25120Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.2143

Unknown

ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING / HYDROLASE
AT4G30870

Predicted

Phenotypic Enhancement

FSW = 0.2215

Unknown

MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING
AT5G26680

Predicted

Synthetic Lethality

synthetic growth defect

Phenotypic Enhancement

FSW = 0.2093

Unknown

ENDONUCLEASE PUTATIVE
AT2G31450

Predicted

Synthetic Lethality

FSW = 0.1369

Unknown

ENDONUCLEASE-RELATED
AT4G25540

Predicted

Phenotypic Enhancement

FSW = 0.2154

Unknown

MSH3 (ARABIDOPSIS HOMOLOG OF DNA MISMATCH REPAIR PROTEIN MSH3) DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT5G55310

Predicted

Phenotypic Enhancement

FSW = 0.0819

Unknown

TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA TOPOISOMERASE TYPE I
AT5G63920

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.2061

Unknown

DNA TOPOISOMERASE III ALPHA PUTATIVE
AT5G46180

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0081

Unknown

DELTA-OAT ORNITHINE-OXO-ACID TRANSAMINASE
AT5G48640

Predicted

Phenotypic Enhancement

FSW = 0.0456

Unknown

CYCLIN FAMILY PROTEIN
AT1G51130

Predicted

Synthetic Lethality

FSW = 0.0871

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN CONTAINS INTERPRO DOMAIN/S NSE4 (INTERPROIPR014854) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT3G207601) HAS 200 BLAST HITS TO 198 PROTEINS IN 89 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 63 FUNGI - 88 PLANTS - 37 VIRUSES - 0 OTHER EUKARYOTES - 12 (SOURCE NCBI BLINK)
AT3G50880

Predicted

synthetic growth defect

FSW = 0.0642

Unknown

HHH-GPD BASE EXCISION DNA REPAIR FAMILY PROTEIN
AT5G02530

Predicted

Affinity Capture-MS

FSW = 0.0068

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT1G27470

Predicted

Affinity Capture-MS

FSW = 0.0078

Unknown

TRANSDUCIN-RELATED / WD-40 REPEAT PROTEIN-RELATED
AT1G19480

Predicted

Phenotypic Enhancement

FSW = 0.1115

Unknown

HHH-GPD BASE EXCISION DNA REPAIR FAMILY PROTEIN
AT5G55300

Predicted

Phenotypic Enhancement

FSW = 0.0938

Unknown

TOP1ALPHA (DNA TOPOISOMERASE I ALPHA) DNA TOPOISOMERASE TYPE I
AT4G09140

Predicted

Phenotypic Enhancement

FSW = 0.2084

Unknown

MLH1 (MUTL-HOMOLOGUE 1) PROTEIN BINDING BRIDGING
AT1G29630

Predicted

Phenotypic Enhancement

FSW = 0.1529

Unknown

NUCLEASE
AT4G36050

Predicted

Synthetic Lethality

Phenotypic Enhancement

synthetic growth defect

Synthetic Lethality

FSW = 0.0618

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT1G14400

Predicted

Phenotypic Enhancement

synthetic growth defect

FSW = 0.0710

Unknown

UBC1 (UBIQUITIN CARRIER PROTEIN 1) UBIQUITIN-PROTEIN LIGASE
AT1G05900

Predicted

Synthetic Lethality

FSW = 0.0871

Unknown

ENDONUCLEASE-RELATED
AT5G39900

Predicted

interaction prediction

FSW = 0.0281

Unknown

GTP BINDING / GTPASE/ TRANSLATION ELONGATION FACTOR
AT4G21540

Predicted

interaction prediction

FSW = 0.0096

Unknown

SPHK1 (SPHINGOSINE KINASE 1) D-ERYTHRO-SPHINGOSINE KINASE/ DIACYLGLYCEROL KINASE/ SPHINGANINE KINASE

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

Learn more

How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454