Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G63920 - ( DNA topoisomerase III alpha putative )
53 Proteins interacs with AT5G63920Locus | Method | FSW | Cellular Compartment Classification (C3) | Description |
---|---|---|---|---|
AT3G11630 | PredictedPhenotypic Enhancement | FSW = 0.1182
| Unknown | 2-CYS PEROXIREDOXIN CHLOROPLAST (BAS1) |
AT4G02070 | PredictedAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.1711
| Unknown | MSH6 (MUTS HOMOLOG 6) DAMAGED DNA BINDING |
AT1G02680 | PredictedPhenotypic Enhancement | FSW = 0.0318
| Unknown | TAF13 (TBP-ASSOCIATED FACTOR 13) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION FACTOR |
AT3G13940 | PredictedSynthetic LethalityCo-expression | FSW = 0.0551
| Unknown | DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
AT5G09860 | Predictedinteraction predictionCo-expression | FSW = 0.0545
| Unknown | NUCLEAR MATRIX PROTEIN-RELATED |
AT1G05120 | PredictedPhenotypic Enhancement | FSW = 0.0935
| Unknown | SNF2 DOMAIN-CONTAINING PROTEIN / HELICASE DOMAIN-CONTAINING PROTEIN / RING FINGER DOMAIN-CONTAINING PROTEIN |
AT1G07370 | PredictedPhenotypic Enhancement | FSW = 0.2338
| Unknown | PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING |
AT3G19210 | PredictedSynthetic RescueSynthetic RescueSynthetic RescueSynthetic Rescue | FSW = 0.2864
| Unknown | ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING |
AT1G63490 | PredictedPhenotypic Enhancement | FSW = 0.0220
| Unknown | TRANSCRIPTION FACTOR JUMONJI (JMJC) DOMAIN-CONTAINING PROTEIN |
AT5G60410 | Predictedbiochemical | FSW = 0.0678
| Unknown | SIZ1 DNA BINDING / SUMO LIGASE |
AT1G35940 | PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.3483
| Unknown | SIZ1 DNA BINDING / SUMO LIGASE |
AT5G41150 | Predictedsynthetic growth defectPhenotypic Enhancement | FSW = 0.2061
| Unknown | UVH1 (ULTRAVIOLET HYPERSENSITIVE 1) SINGLE-STRANDED DNA SPECIFIC ENDODEOXYRIBONUCLEASE |
AT2G31970 | Predictedsynthetic growth defectCo-expression | FSW = 0.2599
| Unknown | RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING |
AT5G57450 | PredictedSynthetic Rescue | FSW = 0.2863
| Unknown | XRCC3 ATP BINDING / DAMAGED DNA BINDING / PROTEIN BINDING / SINGLE-STRANDED DNA BINDING |
AT5G66130 | PredictedPhenotypic Enhancement | FSW = 0.2637
| Unknown | ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE) |
AT5G40820 | PredictedSynthetic Lethality | FSW = 0.2397
| Unknown | ATRAD3 BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR / PROTEIN SERINE/THREONINE KINASE |
AT5G54260 | Predictedsynthetic growth defect | FSW = 0.2293
| Unknown | MRE11 (MEIOTIC RECOMBINATION 11) ENDONUCLEASE/ EXONUCLEASE/ HYDROLASE/ MANGANESE ION BINDING / PROTEIN SERINE/THREONINE PHOSPHATASE |
AT5G20850 | PredictedSynthetic RescueSynthetic RescueSynthetic RescueSynthetic Rescue | FSW = 0.1516
| Unknown | ATRAD51 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ DAMAGED DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING / PROTEIN BINDING / SEQUENCE-SPECIFIC DNA BINDING |
AT1G10930 | Predictedinteraction predictiontwo hybridtwo hybridSynthetic RescueSynthetic RescueSynthetic RescueSynthetic RescueSynthetic RescueSynthetic RescueSynthetic Rescuesynthetic growth defectsynthetic growth defectsynthetic growth defectReconstituted ComplexPhenotypic Enhancementin vivoin vivoin vitroin vitrointerologs mappingco-fractionationCo-fractionationAffinity Capture-WesternAffinity Capture-WesternAffinity Capture-WesternAffinity Capture-Westerntwo hybridPhenotypic Enhancementsynthetic growth defectAffinity Capture-Westerntwo hybridAffinity Capture-WesternAffinity Capture-WesternAffinity Capture-WesternSynthetic RescueSynthetic RescueSynthetic RescueAffinity Capture-Westernfar western blottingAffinity Capture-WesternColocalizationfar western blottingin vivoAffinity Capture-WesternAffinity Capture-Westernfar western blottingColocalizationReconstituted Complexco-fractionationCo-fractionationsynthetic growth defectSynthetic RescuePhenotypic SuppressionPhenotypic Enhancementinterologs mappinginteraction predictionEnriched domain pair | FSW = 0.4450
| Unknown | RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING |
AT3G05740 | Predictedfar western blottingAffinity Capture-WesternColocalizationfar western blottingin vitroin vivoAffinity Capture-WesternAffinity Capture-Westernfar western blottingAffinity Capture-WesternColocalizationin vivoin vitroReconstituted Complex | FSW = 0.1429
| Unknown | RECQI1 (ARABIDOPSIS RECQ HELICASE L1) ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING |
AT4G35740 | Predictedin vivoEnriched domain pairCo-expression | FSW = 0.0367
| Unknown | RECQL3 ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING |
AT1G66740 | PredictedPhenotypic Enhancement | FSW = 0.1682
| Unknown | SGA2 |
AT4G25120 | PredictedSynthetic LethalitySynthetic LethalitySynthetic LethalitySynthetic LethalityPhenotypic Enhancementinteraction prediction | FSW = 0.2338
| Unknown | ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING / HYDROLASE |
AT4G30870 | PredictedSynthetic LethalitySynthetic LethalitySynthetic LethalitySynthetic LethalityPhenotypic Enhancement | FSW = 0.1856
| Unknown | MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING |
AT5G05700 | Predictedtwo hybridAffinity Capture-Western | FSW = 0.0317
| Unknown | ATE1 (ARGININE-TRNA PROTEIN TRANSFERASE 1) ARGINYLTRANSFERASE |
AT5G41700 | PredictedPhenotypic Enhancement | FSW = 0.0590
| Unknown | UBC8 (UBIQUITIN CONJUGATING ENZYME 8) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE |
AT5G41880 | PredictedPhenotypic Enhancement | FSW = 0.0856
| Unknown | POLA3 DNA PRIMASE |
AT1G04730 | PredictedSynthetic Lethalityinteraction predictionCo-expression | FSW = 0.1738
| Unknown | AAA-TYPE ATPASE FAMILY PROTEIN |
AT1G08840 | PredictedSynthetic Lethality | FSW = 0.2709
| Unknown | EMB2411 (EMBRYO DEFECTIVE 2411) ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING |
AT1G18090 | PredictedPhenotypic Enhancement | FSW = 0.1584
| Unknown | EXONUCLEASE PUTATIVE |
AT1G24290 | PredictedPhenotypic EnhancementPhenotypic Enhancement | FSW = 0.1330
| Unknown | AAA-TYPE ATPASE FAMILY PROTEIN |
AT1G29990 | PredictedSynthetic Lethalityinteraction prediction | FSW = 0.0597
| Unknown | PDF6 (PREFOLDIN 6) UNFOLDED PROTEIN BINDING |
AT1G54140 | PredictedPhenotypic Enhancement | FSW = 0.0328
| Unknown | TAFII21 (TATA BINDING PROTEIN ASSOCIATED FACTOR 21KDA SUBUNIT) DNA BINDING / TRANSCRIPTION INITIATION FACTOR |
AT1G55915 | PredictedSynthetic LethalityPhenotypic Enhancement | FSW = 0.1475
| Unknown | ZINC ION BINDING |
AT1G60620 | PredictedPhenotypic Enhancement | FSW = 0.0413
| Unknown | ATRPAC43 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION |
AT1G67190 | Predictedsynthetic growth defect | FSW = 0.1782
| Unknown | F-BOX FAMILY PROTEIN |
AT3G02820 | PredictedSynthetic LethalitySynthetic LethalityPhenotypic Enhancementinteraction predictionCo-expression | FSW = 0.2432
| Unknown | ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN |
AT3G25100 | PredictedSynthetic LethalityCo-expression | FSW = 0.1696
| Unknown | CDC45 (CELL DIVISION CYCLE 45) |
AT3G42660 | PredictedSynthetic Lethalitysynthetic growth defectinteraction predictionCo-expression | FSW = 0.2660
| Unknown | NUCLEOTIDE BINDING |
AT4G16970 | PredictedSynthetic Lethality | FSW = 0.0962
| Unknown | ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE |
AT5G26680 | PredictedSynthetic Lethality | FSW = 0.2307
| Unknown | ENDONUCLEASE PUTATIVE |
AT5G48640 | PredictedPhenotypic Enhancement | FSW = 0.0919
| Unknown | CYCLIN FAMILY PROTEIN |
AT5G49510 | PredictedSynthetic Lethalityinteraction predictionCo-expression | FSW = 0.0682
| Unknown | PDF3 (PREFOLDIN 3) UNFOLDED PROTEIN BINDING |
AT5G55310 | PredictedSynthetic LethalityPhenotypic Enhancement | FSW = 0.1591
| Unknown | TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA TOPOISOMERASE TYPE I |
AT5G59440 | PredictedSynthetic Lethalityinteraction prediction | FSW = 0.0643
| Unknown | ZEU1 (ZEUS1) ATP BINDING / THYMIDYLATE KINASE |
AT5G61460 | Predictedsynthetic growth defect | FSW = 0.0581
| Unknown | MIM (HYPERSENSITIVE TO MMS IRRADIATION AND MMC) ATP BINDING |
AT5G62410 | Predictedinterologs mapping | FSW = 0.0179
| Unknown | SMC2 (STRUCTURAL MAINTENANCE OF CHROMOSOMES 2) TRANSPORTER |
AT1G20610 | Predictedinterologs mapping | FSW = 0.0436
| Unknown | CYCB23 (CYCLIN B23) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR |
AT5G07660 | Predictedsynthetic growth defect | FSW = 0.0574
| Unknown | STRUCTURAL MAINTENANCE OF CHROMOSOMES (SMC) FAMILY PROTEIN |
AT5G55300 | PredictedSynthetic Lethalityinteraction predictionCo-expression | FSW = 0.1711
| Unknown | TOP1ALPHA (DNA TOPOISOMERASE I ALPHA) DNA TOPOISOMERASE TYPE I |
AT3G07120 | PredictedSynthetic Lethality | FSW = 0.2217
| Unknown | ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN |
AT3G11240 | Predictedtwo hybrid | FSW = 0.0111
| Unknown | ATE2 (ARGININE-TRNA PROTEIN TRANSFERASE 2) ARGINYLTRANSFERASE |
AT5G39770 | Predictedinteraction prediction | FSW = 0.0547
| Unknown | DNA BINDING / ENDONUCLEASE/ NUCLEASE/ NUCLEIC ACID BINDING / PROTEIN BINDING |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454