Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT3G13940 - ( DNA binding / DNA-directed RNA polymerase )
66 Proteins interacs with AT3G13940| Locus | Method | FSW  | Cellular Compartment Classification (C3) | Description |
|---|---|---|---|---|
AT1G61000
   | PredictedSynthetic Lethality | FSW = 0.0080
| Class C:nucleus | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN MITOSIS LOCATED IN PLASMA MEMBRANE EXPRESSED IN CULTURED CELL CONTAINS INTERPRO DOMAIN/S KINETOCHORE PROTEIN NUF2 (INTERPROIPR005549) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS MYOSIN HEAVY CHAIN-RELATED (TAIRAT1G643301) HAS 41010 BLAST HITS TO 23184 PROTEINS IN 1264 SPECIES ARCHAE - 616 BACTERIA - 3998 METAZOA - 20566 FUNGI - 2893 PLANTS - 1316 VIRUSES - 149 OTHER EUKARYOTES - 11472 (SOURCE NCBI BLINK) |
| AT5G06680
| PredictedSynthetic LethalityCo-expression | FSW = 0.0145
| Class C:nucleus | SPC98 (SPINDLE POLE BODY COMPONENT 98) TUBULIN BINDING |
| AT4G07950
| PredictedPhenotypic Enhancement | FSW = 0.1218
| Class C:nucleus | DNA-DIRECTED RNA POLYMERASE III FAMILY PROTEIN |
| AT5G67270
| Predictedsynthetic growth defect | FSW = 0.0964
| Class C:nucleus | ATEB1C (MICROTUBULE END BINDING PROTEIN 1) MICROTUBULE BINDING |
| AT4G10710
| PredictedSynthetic Lethality | FSW = 0.0335
| Class C:nucleus | SPT16 (GLOBAL TRANSCRIPTION FACTOR C) |
| AT4G10670
| PredictedSynthetic Lethality | FSW = 0.0231
| Class C:nucleus | GTC2 |
| AT3G57660
| PredictedCo-purificationAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.2541
| Class C:nucleus | NRPA1 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ ZINC ION BINDING |
| AT3G12810
| PredictedPhenotypic Enhancement | FSW = 0.0914
| Class C:nucleus | PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING |
| AT3G05060
| PredictedAffinity Capture-MSAffinity Capture-MSCo-expression | FSW = 0.0134
| Class C:nucleus | SAR DNA-BINDING PROTEIN PUTATIVE |
| AT3G62310
| PredictedAffinity Capture-MS | FSW = 0.0241
| Class C:nucleus | RNA HELICASE PUTATIVE |
| AT2G41500
| PredictedAffinity Capture-MSCo-expression | FSW = 0.0072
| Class C:nucleus | EMB2776 NUCLEOTIDE BINDING |
| AT3G25940
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.2966
| Class C:nucleus | TRANSCRIPTION FACTOR S-II (TFIIS) DOMAIN-CONTAINING PROTEIN |
| AT1G30590
| PredictedCo-purificationSynthetic Lethality | FSW = 0.0155
| Class C:nucleus | RNA POLYMERASE I SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3 FAMILY PROTEIN |
| AT1G07370
| PredictedSynthetic LethalityCo-expression | FSW = 0.0604
| Class C:nucleus | PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING |
| AT2G13370
| PredictedPhenotypic Suppression | FSW = 0.0713
| Class C:nucleus | CHR5 (CHROMATIN REMODELING 5) ATP BINDING / DNA BINDING / CHROMATIN BINDING / HELICASE/ NUCLEIC ACID BINDING |
| AT4G08350
| PredictedAffinity Capture-MS | FSW = 0.0509
| Class C:nucleus | GTA2 (GLOBAL TRANSCRIPTION FACTOR GROUP A2) STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION FACTOR |
| AT5G41020
| PredictedAffinity Capture-MS | FSW = 0.0312
| Class C:nucleus | MYB FAMILY TRANSCRIPTION FACTOR |
| AT2G34210
| PredictedAffinity Capture-MS | FSW = 0.0500
| Class C:nucleus | STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION INITIATION FACTOR |
| AT3G60500
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0214
| Class C:nucleus | CER7 (ECERIFERUM 7) 3-5-EXORIBONUCLEASE/ RNA BINDING |
| AT5G45130
| PredictedPhenotypic Enhancement | FSW = 0.0149
| Unknown | RHA1 (RAB HOMOLOG 1) GTP BINDING |
| AT5G13710
| PredictedPhenotypic Suppression | FSW = 0.0508
| Unknown | SMT1 (STEROL METHYLTRANSFERASE 1) STEROL 24-C-METHYLTRANSFERASE |
| AT2G31170
| PredictedSynthetic Lethality | FSW = 0.0027
| Unknown | SYCO ARATH ATP BINDING / AMINOACYL-TRNA LIGASE/ CYSTEINE-TRNA LIGASE/ NUCLEOTIDE BINDING |
| AT3G11630
| Predictedsynthetic growth defect | FSW = 0.0107
| Unknown | 2-CYS PEROXIREDOXIN CHLOROPLAST (BAS1) |
| AT3G12110
| PredictedPhenotypic Enhancement | FSW = 0.0145
| Unknown | ACT11 (ACTIN-11) STRUCTURAL CONSTITUENT OF CYTOSKELETON |
| AT1G32210
| PredictedSynthetic Lethality | FSW = 0.0155
| Unknown | ATDAD1 (DEFENDER AGAINST APOPTOTIC DEATH 1) |
| AT3G47690
| Predictedsynthetic growth defect | FSW = 0.0759
| Unknown | ATEB1A MICROTUBULE BINDING |
| AT5G19910
| PredictedPhenotypic Suppression | FSW = 0.0880
| Unknown | SOH1 FAMILY PROTEIN |
| AT1G61700
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.1513
| Unknown | DNA-DIRECTED RNA POLYMERASE II PUTATIVE (RPB10) |
| AT2G22310
| PredictedPhenotypic Suppression | FSW = 0.0291
| Unknown | ATUBP4 (ARABIDOPSIS THALIANA UBIQUITIN-SPECIFIC PROTEASE 4) UBIQUITIN-SPECIFIC PROTEASE |
| AT3G56340
| PredictedAffinity Capture-MS | FSW = 0.0064
| Unknown | 40S RIBOSOMAL PROTEIN S26 (RPS26C) |
| AT2G29540
| PredictedAffinity Capture-MSAffinity Capture-MSCo-expression | FSW = 0.0828
| Unknown | ATRPC14 (RNA POLYMERASE 14 KDA SUBUNIT) DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION |
| AT1G08780
| PredictedPhenotypic Suppression | FSW = 0.0917
| Unknown | AIP3 (ABI3-INTERACTING PROTEIN 3) UNFOLDED PROTEIN BINDING |
| AT1G10930
| PredictedSynthetic Rescue | FSW = 0.0294
| Unknown | RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING |
| AT1G21170 | PredictedSynthetic Lethality | FSW = 0.0072
| Unknown | SEC5B |
| AT1G29940 | PredictedCo-purificationAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSSynthetic Lethalityinterologs mappingCo-expression | FSW = 0.1980
| Unknown | NRPA2 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ RIBONUCLEOSIDE BINDING |
| AT1G34150
| PredictedPhenotypic Suppression | FSW = 0.0473
| Unknown | TRNA PSEUDOURIDINE SYNTHASE FAMILY PROTEIN |
| AT1G49540
| PredictedPhenotypic Suppression | FSW = 0.0983
| Unknown | NUCLEOTIDE BINDING |
| AT1G51310
| PredictedPhenotypic Suppression | FSW = 0.0631
| Unknown | TRNA (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE |
| AT1G54250
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.2071
| Unknown | NRPB8A DNA-DIRECTED RNA POLYMERASE |
| AT1G60620
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinteraction prediction | FSW = 0.1263
| Unknown | ATRPAC43 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION |
| AT2G27970
| PredictedPhenotypic Enhancement | FSW = 0.0270
| Unknown | CKS2 (CDK-SUBUNIT 2) CYCLIN-DEPENDENT PROTEIN KINASE/ CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR |
| AT2G34750
| PredictedSynthetic LethalitySynthetic LethalityCo-purification | FSW = 0.0174
| Unknown | RNA POLYMERASE I SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3 FAMILY PROTEIN |
| AT3G22320
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSCo-expression | FSW = 0.1562
| Unknown | NRPB5 DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
| AT3G45630
| PredictedSynthetic Lethality | FSW = 0.0035
| Unknown | RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN |
| AT5G44750
| PredictedPhenotypic Enhancement | FSW = 0.0122
| Unknown | REV1 DNA-DIRECTED DNA POLYMERASE |
| AT5G50320
| PredictedPhenotypic Suppression | FSW = 0.0868
| Unknown | ELO3 (ELONGATA 3) HISTONE ACETYLTRANSFERASE |
| AT5G55310
| PredictedPhenotypic Enhancementinterologs mappingSynthetic Lethality | FSW = 0.0675
| Unknown | TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA TOPOISOMERASE TYPE I |
| AT3G21060
| PredictedPhenotypic Enhancement | FSW = 0.0496
| Unknown | TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN |
| AT3G22480
| PredictedPhenotypic Suppression | FSW = 0.0762
| Unknown | PREFOLDIN-RELATED KE2 FAMILY PROTEIN |
| AT3G25100
| PredictedSynthetic LethalityCo-expression | FSW = 0.0308
| Unknown | CDC45 (CELL DIVISION CYCLE 45) |
| AT4G33100
| PredictedPhenotypic Suppression | FSW = 0.0224
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY FAMILY 35/APOPTOSIS (INTERPROIPR007918) HAS 160 BLAST HITS TO 160 PROTEINS IN 70 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 95 FUNGI - 46 PLANTS - 13 VIRUSES - 0 OTHER EUKARYOTES - 6 (SOURCE NCBI BLINK) |
| AT5G02880
| PredictedPhenotypic Enhancement | FSW = 0.0075
| Unknown | UPL4 UBIQUITIN-PROTEIN LIGASE |
| AT5G13780
| PredictedPhenotypic Enhancement | FSW = 0.0230
| Unknown | GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE |
| AT5G41340
| PredictedPhenotypic Suppression | FSW = 0.0376
| Unknown | UBC4 (UBIQUITIN CONJUGATING ENZYME 4) UBIQUITIN-PROTEIN LIGASE |
| AT5G45600
| PredictedPhenotypic Suppression | FSW = 0.0905
| Unknown | GAS41 PROTEIN BINDING |
| AT5G50870
| PredictedSynthetic Lethality | FSW = 0.0122
| Unknown | UBC27 (UBIQUITIN-CONJUGATING ENZYME 27) UBIQUITIN-PROTEIN LIGASE |
| AT5G51940
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MS | FSW = 0.1482
| Unknown | NRPB6A DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
| AT5G61770
| PredictedPhenotypic Suppression | FSW = 0.0484
| Unknown | PPAN (PETER PAN-LIKE PROTEIN) |
| AT5G63920
| PredictedSynthetic LethalityCo-expression | FSW = 0.0551
| Unknown | DNA TOPOISOMERASE III ALPHA PUTATIVE |
| AT5G65180
| PredictedPhenotypic Enhancement | FSW = 0.1089
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN EXPRESSED IN 18 PLANT STRUCTURES EXPRESSED DURING 9 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S PROTEIN OF UNKNOWN FUNCTION DUF618 (INTERPROIPR006903) REGULATION OF NUCLEAR PRE-MRNA PROTEIN (INTERPROIPR006569) ENTH/VHS (INTERPROIPR008942) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT5G100601) HAS 3523 BLAST HITS TO 3241 PROTEINS IN 333 SPECIES ARCHAE - 25 BACTERIA - 251 METAZOA - 1575 FUNGI - 421 PLANTS - 142 VIRUSES - 17 OTHER EUKARYOTES - 1092 (SOURCE NCBI BLINK) |
| AT3G19420
| PredictedAffinity Capture-MS | FSW = 0.0122
| Unknown | ATPEN2 (ARABIDOPSIS THALIANA PTEN 2) PHOSPHATASE/ PROTEIN TYROSINE PHOSPHATASE |
| AT1G11475
| PredictedAffinity Capture-MS | FSW = 0.1443
| Unknown | NRPB10 DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
| AT2G04630
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSCo-expression | FSW = 0.1778
| Unknown | NRPB6B DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
| AT3G12990
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0177
| Unknown | RRP45A (RIBONUCLEASE PH45A) 3-5-EXORIBONUCLEASE/ RNA BINDING |
| AT3G09670
| PredictedAffinity Capture-MSCo-expression | FSW = 0.0245
| Unknown | PWWP DOMAIN-CONTAINING PROTEIN |
| AT1G11240
| PredictedSynthetic LethalityCo-expression | FSW = 0.0142
| Unknown | UNKNOWN PROTEIN |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
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