Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT2G29570 - ( PCNA2 (PROLIFERATING CELL NUCLEAR ANTIGEN 2) DNA binding / DNA polymerase processivity factor )

71 Proteins interacs with AT2G29570
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT5G44740

Experimental

pull down

two hybrid

FSW = 0.0220

Unknown

 POLH (Y-FAMILT DNA POLYMERASE H) DNA-DIRECTED DNA POLYMERASE
YDR419WExperimental

two hybrid

FSW = 0.0272

Unknown

 POLH (Y-FAMILT DNA POLYMERASE H) DNA-DIRECTED DNA POLYMERASE
AT5G67630

Predicted

in vitro

Co-expression

FSW = 0.0059

Class C:

nucleus

 DNA HELICASE PUTATIVE
AT3G48750

Predicted

in vitro

FSW = 0.0249

Class C:

nucleus

 CDC2 (CELL DIVISION CONTROL 2) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT1G16970

Predicted

in vitro

in vivo

in vivo

in vitro

Affinity Capture-MS

FSW = 0.1277

Class C:

nucleus

 KU70 (ARABIDOPSIS THALIANA KU70 HOMOLOG) DOUBLE-STRANDED DNA BINDING / PROTEIN BINDING
AT1G08130

Predicted

in vitro

Reconstituted Complex

Co-expression

FSW = 0.1355

Class C:

nucleus

 ATLIG1 (ARABIDOPSIS THALIANA DNA LIGASE 1) ATP BINDING / DNA BINDING / DNA LIGASE (ATP)
AT1G48050

Predicted

in vivo

in vitro

FSW = 0.0919

Class C:

nucleus

 KU80 DOUBLE-STRANDED DNA BINDING / PROTEIN BINDING
AT5G57015

Predicted

two hybrid

FSW = 0.0049

Class C:

nucleus

 CKL12 (CASEIN KINASE I-LIKE 12) ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT4G02070

Predicted

in vitro

in vitro

Affinity Capture-MS

Co-expression

FSW = 0.1345

Class C:

nucleus

 MSH6 (MUTS HOMOLOG 6) DAMAGED DNA BINDING
AT1G21690

Predicted

in vivo

in vivo

in vitro

in vitro

Affinity Capture-MS

Co-expression

FSW = 0.2120

Class C:

nucleus

 EMB1968 (EMBRYO DEFECTIVE 1968) ATP BINDING / ATPASE/ DNA BINDING / DNA CLAMP LOADER/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT4G38130

Predicted

Affinity Capture-MS

Reconstituted Complex

Affinity Capture-Western

in vitro

in vivo

Co-expression

FSW = 0.0488

Class C:

nucleus

 HD1 (HISTONE DEACETYLASE 1) BASAL TRANSCRIPTION REPRESSOR/ HISTONE DEACETYLASE/ PROTEIN BINDING
AT5G45400

Predicted

in vitro

Co-expression

FSW = 0.0229

Class C:

nucleus

 REPLICATION PROTEIN PUTATIVE
AT5G61000

Predicted

in vitro

FSW = 0.0281

Class C:

nucleus

 REPLICATION PROTEIN PUTATIVE
AT1G65470

Predicted

in vitro

two hybrid

FSW = 0.0980

Class C:

nucleus

 FAS1 (FASCIATA 1) HISTONE BINDING
AT1G07370

Predicted

Enriched domain pair

Phylogenetic profile method

Co-expression

FSW = 0.1913

Class C:

nucleus

 PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING
AT3G15000

Predicted

two hybrid

FSW = 0.0146

Unknown

 LOCATED IN MITOCHONDRION EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS PLASTID DEVELOPMENTAL PROTEIN DAG PUTATIVE (TAIRAT3G067902) HAS 50779 BLAST HITS TO 24732 PROTEINS IN 941 SPECIES ARCHAE - 10 BACTERIA - 4862 METAZOA - 25623 FUNGI - 7071 PLANTS - 6957 VIRUSES - 900 OTHER EUKARYOTES - 5356 (SOURCE NCBI BLINK)
AT4G32520

Predicted

two hybrid

FSW = 0.0146

Unknown

 SHM3 (SERINE HYDROXYMETHYLTRANSFERASE 3) CATALYTIC/ GLYCINE HYDROXYMETHYLTRANSFERASE/ PYRIDOXAL PHOSPHATE BINDING
AT3G18524

Predicted

in vitro

in vitro

Affinity Capture-MS

Co-expression

FSW = 0.1385

Unknown

 MSH2 (MUTS HOMOLOG 2) ATP BINDING / DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT4G38680

Predicted

in vitro

in vivo

FSW = 0.0042

Unknown

 GRP2 (GLYCINE RICH PROTEIN 2) DOUBLE-STRANDED DNA BINDING / MRNA BINDING / NUCLEIC ACID BINDING / SINGLE-STRANDED DNA BINDING
AT2G41460

Predicted

in vivo

Affinity Capture-MS

Co-expression

FSW = 0.0954

Unknown

 ARP DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE
AT5G66130

Predicted

synthetic growth defect

FSW = 0.1872

Unknown

 ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT5G63960

Predicted

in vivo

in vitro

in vitro

Affinity Capture-MS

Co-expression

FSW = 0.1793

Unknown

 EMB2780 (EMBRYO DEFECTIVE 2780) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING
AT2G42120

Predicted

in vivo

Affinity Capture-MS

two hybrid

Co-expression

FSW = 0.0519

Unknown

 POLD2 (DNA POLYMERASE DELTA SMALL SUBUNIT) DNA BINDING / DNA-DIRECTED DNA POLYMERASE
AT5G09250

Predicted

two hybrid

Affinity Capture-MS

FSW = 0.0144

Unknown

 KIWI DNA BINDING / PROTEIN BINDING / TRANSCRIPTION COACTIVATOR
AT3G28030

Predicted

synthetic growth defect

FSW = 0.0351

Unknown

 UVH3 (ULTRAVIOLET HYPERSENSITIVE 3) DNA BINDING / CATALYTIC/ ENDONUCLEASE/ NUCLEASE/ SINGLE-STRANDED DNA BINDING
AT4G02570

Predicted

two hybrid

FSW = 0.0088

Unknown

 ATCUL1 (ARABIDOPSIS THALIANA CULLIN 1) PROTEIN BINDING
AT5G40820

Predicted

synthetic growth defect

FSW = 0.1395

Unknown

 ATRAD3 BINDING / INOSITOL OR PHOSPHATIDYLINOSITOL KINASE/ PHOSPHOTRANSFERASE ALCOHOL GROUP AS ACCEPTOR / PROTEIN SERINE/THREONINE KINASE
AT5G22010

Predicted

in vivo

in vivo

in vivo

in vitro

in vitro

in vitro

two hybrid

FSW = 0.1788

Unknown

 ATRFC1 (REPLICATION FACTOR C 1) ATP BINDING / DNA BINDING / DNA CLAMP LOADER/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT4G17760

Predicted

two hybrid

FSW = 0.0419

Unknown

 DAMAGED DNA BINDING / EXODEOXYRIBONUCLEASE III
AT1G16350

Predicted

two hybrid

FSW = 0.0153

Unknown

 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE PUTATIVE
AT1G16590

Predicted

two hybrid

FSW = 0.0500

Unknown

 REV7 DNA BINDING
AT5G47650

Predicted

two hybrid

FSW = 0.0351

Unknown

 ATNUDT2 (ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 2) ADP-RIBOSE DIPHOSPHATASE/ NAD OR NADH BINDING / HYDROLASE
AT3G57870

Predicted

two hybrid

FSW = 0.0237

Unknown

 SCE1 (SUMO CONJUGATION ENZYME 1) SUMO LIGASE
AT5G12980

Predicted

two hybrid

FSW = 0.0304

Unknown

 RCD1-LIKE CELL DIFFERENTIATION PROTEIN PUTATIVE
AT5G41770

Predicted

two hybrid

FSW = 0.0155

Unknown

 CROOKED NECK PROTEIN PUTATIVE / CELL CYCLE PROTEIN PUTATIVE
AT5G42190

Predicted

two hybrid

FSW = 0.0132

Unknown

 ASK2 (ARABIDOPSIS SKP1-LIKE 2) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT1G04730Predicted

in vitro

in vivo

FSW = 0.0643

Unknown

 AAA-TYPE ATPASE FAMILY PROTEIN
AT1G08260

Predicted

in vitro

FSW = 0.0894

Unknown

 TIL1 (TILTED 1) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING
AT1G18090

Predicted

Affinity Capture-MS

FSW = 0.1060

Unknown

 EXONUCLEASE PUTATIVE
AT1G29630

Predicted

Affinity Capture-MS

FSW = 0.0690

Unknown

 NUCLEASE
AT1G58050

Predicted

in vitro

FSW = 0.0166

Unknown

 HELICASE DOMAIN-CONTAINING PROTEIN
AT1G63160

Predicted

in vitro

in vitro

in vitro

in vitro

in vitro

Co-expression

FSW = 0.1039

Unknown

 REPLICATION FACTOR C 40 KDA PUTATIVE
AT1G77470

Predicted

in vitro

in vitro

in vitro

in vitro

Affinity Capture-MS

Co-expression

FSW = 0.1220

Unknown

 REPLICATION FACTOR C 36 KDA PUTATIVE
AT1G80420

Predicted

Affinity Capture-Western

fluorescence acceptor donor pair

Reconstituted Complex

Colocalization

in vitro

in vivo

two hybrid

FSW = 0.0602

Unknown

 DNA REPAIR PROTEIN PUTATIVE (XRCC1)
AT2G27120

Predicted

in vitro

FSW = 0.1250

Unknown

 TIL2 (TILTED 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING
AT1G07270

Predicted

two hybrid

Co-expression

FSW = 0.0365

Unknown

 CELL DIVISION CONTROL PROTEIN CDC6B PUTATIVE (CDC6B)
AT1G78650

Predicted

in vitro

in vitro

in vitro

Co-expression

FSW = 0.0454

Unknown

 POLD3 DNA-DIRECTED DNA POLYMERASE
AT2G29680

Predicted

two hybrid

FSW = 0.0159

Unknown

 CDC6 (CELL DIVISION CONTROL 6)
AT3G05480

Predicted

in vitro

Affinity Capture-MS

synthetic growth defect

FSW = 0.1481

Unknown

 RAD9
AT3G23590

Predicted

Affinity Capture-Western

in vivo

in vitro

FSW = 0.0981

Unknown

 RFR1 (REF4-RELATED 1)
AT4G12740

Predicted

in vivo

in vitro

Affinity Capture-MS

Affinity Capture-Western

Reconstituted Complex

FSW = 0.0923

Unknown

 ADENINE-DNA GLYCOSYLASE-RELATED / MYH-RELATED
AT4G25540

Predicted

in vivo

in vivo

in vivo

in vitro

in vitro

in vitro

Co-expression

FSW = 0.0941

Unknown

 MSH3 (ARABIDOPSIS HOMOLOG OF DNA MISMATCH REPAIR PROTEIN MSH3) DAMAGED DNA BINDING / MISMATCHED DNA BINDING / PROTEIN BINDING
AT5G06150

Predicted

in vivo

FSW = 0.0151

Unknown

 CYC1BAT CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT5G10220

Predicted

in vitro

in vivo

in vivo

in vitro

Affinity Capture-MS

FSW = 0.0200

Unknown

 ANN6 (ANNEXIN ARABIDOPSIS 6) CALCIUM ION BINDING / CALCIUM-DEPENDENT PHOSPHOLIPID BINDING
AT5G11300

Predicted

Affinity Capture-Western

FSW = 0.0956

Unknown

 CYC3B (MITOTIC-LIKE CYCLIN 3B FROM ARABIDOPSIS) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT5G26680

Predicted

two hybrid

two hybrid

two hybrid

two hybrid

two hybrid

in vivo

in vivo

in vivo

in vivo

in vivo

in vitro

in vitro

in vitro

in vitro

in vitro

Affinity Capture-MS

Reconstituted Complex

Reconstituted Complex

synthetic growth defect

Co-expression

FSW = 0.1534

Unknown

 ENDONUCLEASE PUTATIVE
AT5G27680

Predicted

in vivo

in vivo

in vitro

in vitro

Affinity Capture-Western

FSW = 0.0694

Unknown

 RECQSIM (ARABIDOPSIS RECQ HELICASE SIM) ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT5G27740

Predicted

in vitro

in vitro

Affinity Capture-Western

Co-expression

FSW = 0.1531

Unknown

 EMB2775 (EMBRYO DEFECTIVE 2775) DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT5G55000

Predicted

in vitro

in vivo

Affinity Capture-MS

FSW = 0.0495

Unknown

 FIP2 PROTEIN BINDING / VOLTAGE-GATED POTASSIUM CHANNEL
AT5G64420

Predicted

in vitro

Co-expression

FSW = 0.0309

Unknown

 DNA POLYMERASE V FAMILY
AT2G44580

Predicted

Affinity Capture-MS

FSW = 0.0310

Unknown

 PROTEIN BINDING / ZINC ION BINDING
AT3G18630

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0337

Unknown

 URACIL DNA GLYCOSYLASE FAMILY PROTEIN
AT3G54180

Predicted

in vitro

FSW = 0.0476

Unknown

 CDKB11 (CYCLIN-DEPENDENT KINASE B11) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING
AT4G08990

Predicted

in vitro

in vitro

Affinity Capture-Western

FSW = 0.0278

Unknown

 DNA (CYTOSINE-5-)-METHYLTRANSFERASE PUTATIVE
AT5G44750

Predicted

Affinity Capture-Western

Co-purification

FSW = 0.0114

Unknown

 REV1 DNA-DIRECTED DNA POLYMERASE
AT1G10520

Predicted

in vitro

in vitro

Affinity Capture-MS

in vitro

FSW = 0.0401

Unknown

 DNA POLYMERASE LAMBDA (POLL)
AT4G36050

Predicted

Affinity Capture-MS

in vitro

in vivo

FSW = 0.0103

Unknown

 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT1G52530

Predicted

Affinity Capture-MS

two hybrid

FSW = 0.1181

Unknown

 FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 7 PLANT STRUCTURES EXPRESSED DURING F MATURE EMBRYO STAGE PETAL DIFFERENTIATION AND EXPANSION STAGE D BILATERAL STAGE E EXPANDED COTYLEDON STAGE CONTAINS INTERPRO DOMAIN/S HUS1-LIKE PROTEIN (INTERPROIPR007150) HAS 88 BLAST HITS TO 87 PROTEINS IN 31 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 51 FUNGI - 6 PLANTS - 21 VIRUSES - 0 OTHER EUKARYOTES - 10 (SOURCE NCBI BLINK)
AT1G79000

Predicted

in vitro

in vivo

FSW = 0.0123

Unknown

 HAC1 (HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 1) H3/H4 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE/ TRANSCRIPTION COFACTOR
AT5G25380

Predicted

in vivo

FSW = 0.0383

Unknown

 CYCA21 (CYCLIN A21) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT2G31320

Predicted

in vivo

Co-expression

FSW = 0.0369

Unknown

 PARP2 (POLY(ADP-RIBOSE) POLYMERASE 2) DNA BINDING / NAD OR NADH BINDING / NAD+ ADP-RIBOSYLTRANSFERASE/ ZINC ION BINDING

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454

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