Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT3G23890 - ( TOPII (TOPOISOMERASE II) ATP binding / DNA binding / DNA topoisomerase (ATP-hydrolyzing)/ DNA topoisomerase/ DNA-dependent ATPase )

48 Proteins interacs with AT3G23890
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G07790

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0680

Unknown

HTB1 DNA BINDING
AT5G47690

Predicted

interologs mapping

FSW = 0.0671

Unknown

BINDING
AT5G59950

Predicted

interaction prediction

FSW = 0.0331

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT2G44680

Predicted

in vitro

interologs mapping

interaction prediction

FSW = 0.0616

Unknown

CKB4 (CASEIN KINASE II BETA SUBUNIT 4) PROTEIN SERINE/THREONINE KINASE
AT5G37720

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0184

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT4G10710

Predicted

Affinity Capture-MS

FSW = 0.0972

Unknown

SPT16 (GLOBAL TRANSCRIPTION FACTOR C)
AT4G10670

Predicted

Affinity Capture-MS

FSW = 0.1409

Unknown

GTC2
AT5G09860

Predicted

interaction prediction

Co-expression

FSW = 0.0595

Unknown

NUCLEAR MATRIX PROTEIN-RELATED
AT4G38130

Predicted

Reconstituted Complex

Affinity Capture-Western

Reconstituted Complex

two hybrid

FSW = 0.0458

Unknown

HD1 (HISTONE DEACETYLASE 1) BASAL TRANSCRIPTION REPRESSOR/ HISTONE DEACETYLASE/ PROTEIN BINDING
AT3G12860

Predicted

Affinity Capture-MS

interaction prediction

Co-expression

FSW = 0.0151

Unknown

NUCLEOLAR PROTEIN NOP56 PUTATIVE
AT1G56110

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0276

Unknown

NOP56 (ARABIDOPSIS HOMOLOG OF NUCLEOLAR PROTEIN NOP56)
AT3G28730

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.1244

Unknown

ATHMG (ARABIDOPSIS THALIANA HIGH MOBILITY GROUP) TRANSCRIPTION FACTOR
AT4G26840

Predicted

interaction prediction

Colocalization

biochemical

Affinity Capture-Western

Affinity Capture-MS

two hybrid

Co-expression

FSW = 0.0413

Unknown

SUMO1 (SMALL UBIQUITIN-LIKE MODIFIER 1) PROTEIN BINDING / PROTEIN TAG
AT3G05740

Predicted

two hybrid

FSW = 0.0108

Unknown

RECQI1 (ARABIDOPSIS RECQ HELICASE L1) ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT5G06420

Predicted

two hybrid

FSW = 0.0085

Unknown

ZINC FINGER (CCCH-TYPE/C3HC4-TYPE RING FINGER) FAMILY PROTEIN
AT1G77320

Predicted

two hybrid

in vitro

FSW = 0.0627

Unknown

MEI1 (MEIOSIS DEFECTIVE 1) TRANSCRIPTION COACTIVATOR
AT4G02110

Predicted

in vitro

two hybrid

FSW = 0.0183

Unknown

TRANSCRIPTION COACTIVATOR
AT5G48700

Predicted

in vivo

in vitro

two hybrid

FSW = 0.0256

Unknown

UBIQUITIN-RELATED
AT5G47080

Predicted

in vitro

FSW = 0.0141

Unknown

CKB1 PROTEIN KINASE REGULATOR
AT1G08880

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0727

Unknown

H2AXA DNA BINDING
AT1G30580

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0165

Unknown

GTP BINDING
AT2G17510

Predicted

Affinity Capture-MS

FSW = 0.0112

Unknown

EMB2763 (EMBRYO DEFECTIVE 2763) RNA BINDING / RIBONUCLEASE
AT2G23070

Predicted

interaction prediction

Affinity Capture-MS

interologs mapping

FSW = 0.0477

Unknown

CASEIN KINASE II ALPHA CHAIN PUTATIVE
AT1G05910

Predicted

Affinity Capture-MS

FSW = 0.0599

Unknown

CELL DIVISION CYCLE PROTEIN 48-RELATED / CDC48-RELATED
AT1G17720

Predicted

Synthetic Rescue

FSW = 0.0349

Unknown

ATB BETA NUCLEOTIDE BINDING / PROTEIN PHOSPHATASE TYPE 2A REGULATOR
AT2G45500

Predicted

Affinity Capture-MS

FSW = 0.0636

Unknown

ATP BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT3G09100

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

Co-expression

FSW = 0.0561

Unknown

MRNA CAPPING ENZYME FAMILY PROTEIN
AT4G25120Predicted

two hybrid

FSW = 0.0333

Unknown

ATP BINDING / ATP-DEPENDENT DNA HELICASE/ DNA BINDING / HYDROLASE
AT4G33620Predicted

interologs mapping

interologs mapping

Synthetic Rescue

FSW = 0.1309

Unknown

ULP1 PROTEASE FAMILY PROTEIN
AT5G55310

Predicted

Phenotypic Enhancement

synthetic growth defect

Phenotypic Enhancement

Synthetic Lethality

synthetic growth defect

FSW = 0.0880

Unknown

TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA TOPOISOMERASE TYPE I
AT3G49470

Predicted

Affinity Capture-MS

FSW = 0.0805

Unknown

NACA2 (NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-LIKE PROTEIN 2)
AT4G30870

Predicted

synthetic growth defect

FSW = 0.0762

Unknown

MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING
AT5G05700

Predicted

two hybrid

FSW = 0.0193

Unknown

ATE1 (ARGININE-TRNA PROTEIN TRANSFERASE 1) ARGINYLTRANSFERASE
AT5G27740

Predicted

Affinity Capture-MS

interaction prediction

Co-expression

FSW = 0.0285

Unknown

EMB2775 (EMBRYO DEFECTIVE 2775) DNA BINDING / NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT5G38890

Predicted

Affinity Capture-MS

FSW = 0.0108

Unknown

EXORIBONUCLEASE-RELATED
AT5G55300

Predicted

Synthetic Lethality

synthetic growth defect

synthetic growth defect

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Synthetic Lethality

synthetic growth defect

Co-expression

FSW = 0.2097

Unknown

TOP1ALPHA (DNA TOPOISOMERASE I ALPHA) DNA TOPOISOMERASE TYPE I
AT5G61460

Predicted

Phenotypic Enhancement

Synthetic Lethality

FSW = 0.0636

Unknown

MIM (HYPERSENSITIVE TO MMS IRRADIATION AND MMC) ATP BINDING
AT5G02530

Predicted

Affinity Capture-MS

Affinity Capture-MS

Co-expression

FSW = 0.0374

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT1G33040

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.0343

Unknown

NACA5 (NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-LIKE PROTEIN 5)
AT2G23080

Predicted

Affinity Capture-MS

FSW = 0.0964

Unknown

CASEIN KINASE II ALPHA CHAIN PUTATIVE
AT3G09670

Predicted

Affinity Capture-MS

Co-expression

FSW = 0.1091

Unknown

PWWP DOMAIN-CONTAINING PROTEIN
AT3G07120

Predicted

Affinity Capture-MS

FSW = 0.0431

Unknown

ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN
AT1G77600

Predicted

interologs mapping

Co-expression

FSW = 0.0399

Unknown

BINDING
AT5G15770

Predicted

interologs mapping

interaction prediction

FSW = 0.0318

Unknown

ATGNA1 (ARABIDOPSIS THALIANA GLUCOSE-6-PHOSPHATE ACETYLTRANSFERASE 1) N-ACETYLTRANSFERASE/ GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE
AT3G03110

Predicted

in vitro

in vivo

Co-expression

FSW = 0.0089

Unknown

XPO1B BINDING / PROTEIN TRANSPORTER
AT1G10930

Predicted

two hybrid

interaction prediction

FSW = 0.0477

Unknown

RECQ4A ATP BINDING / ATP-DEPENDENT HELICASE/ HELICASE/ NUCLEIC ACID BINDING
AT1G01350

Predicted

two hybrid

FSW = 0.0349

Unknown

NUCLEIC ACID BINDING / PROTEIN BINDING / ZINC ION BINDING
AT5G67380

Predicted

interaction prediction

FSW = 0.0576

Unknown

CKA1 (CASEIN KINASE ALPHA 1) KINASE

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454