Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT2G16440 - ( DNA replication licensing factor putative )

27 Proteins interacs with AT2G16440
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G58510

Predicted

Synthetic Rescue

FSW = 0.0278

Unknown

DEAD BOX RNA HELICASE PUTATIVE (RH11)
AT2G24490

Predicted

two hybrid

FSW = 0.1022

Unknown

RPA2 (REPLICON PROTEIN A2) PROTEIN BINDING
AT3G02920

Predicted

two hybrid

FSW = 0.2699

Unknown

REPLICATION PROTEIN-RELATED
AT1G44900

Predicted

Co-purification

Colocalization

Colocalization

co-fractionation

Co-fractionation

Affinity Capture-Western

Affinity Capture-Western

Synthetic Lethality

Affinity Capture-Western

Affinity Capture-Western

Colocalization

two hybrid

Reconstituted Complex

two hybrid

Colocalization

Co-purification

co-fractionation

Co-fractionation

Synthetic Lethality

Affinity Capture-Western

Co-expression

FSW = 0.5051

Unknown

ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE
AT5G45400

Predicted

two hybrid

FSW = 0.2735

Unknown

REPLICATION PROTEIN PUTATIVE
AT5G61000

Predicted

two hybrid

FSW = 0.2092

Unknown

REPLICATION PROTEIN PUTATIVE
AT4G02060

Predicted

in vivo

in vivo

in vivo

in vivo

in vivo

in vivo

Co-purification

Colocalization

Reconstituted Complex

Affinity Capture-Western

Affinity Capture-Western

Synthetic Lethality

Co-purification

Co-purification

Reconstituted Complex

Co-purification

Affinity Capture-Western

Co-expression

FSW = 0.5586

Unknown

PRL (PROLIFERA) ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT5G66130

Predicted

Phenotypic Enhancement

FSW = 0.0326

Unknown

ATRAD17 (ARABIDOPSIS THALIANA RADIATION SENSITIVE)
AT1G26840

Predicted

two hybrid

FSW = 0.5538

Unknown

ORC6 (ORIGIN RECOGNITION COMPLEX PROTEIN 6) DNA BINDING
AT2G37560

Predicted

Synthetic Lethality

two hybrid

interaction prediction

Co-expression

FSW = 0.3572

Unknown

ORC2 (ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2) DNA REPLICATION ORIGIN BINDING / PROTEIN BINDING
AT3G25100

Predicted

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

interologs mapping

synthetic growth defect

Colocalization

FSW = 0.2007

Unknown

CDC45 (CELL DIVISION CYCLE 45)
AT2G01120

Predicted

two hybrid

FSW = 0.5045

Unknown

ORC4 (ORIGIN RECOGNITION COMPLEX SUBUNIT 4) PROTEIN BINDING
AT4G12620

Predicted

two hybrid

FSW = 0.2948

Unknown

ORC1B (ORIGIN OF REPLICATION COMPLEX 1B) DNA BINDING / DOUBLE-STRANDED METHYLATED DNA BINDING / PROTEIN BINDING
AT4G16970

Predicted

biochemical

two hybrid

biochemical

Reconstituted Complex

synthetic growth defect

FSW = 0.2149

Unknown

ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT4G29910

Predicted

two hybrid

FSW = 0.1895

Unknown

ORC5 (ORIGIN RECOGNITION COMPLEX PROTEIN 5) PROTEIN BINDING
AT5G16690

Predicted

two hybrid

FSW = 0.2721

Unknown

ORC3 (ORIGIN RECOGNITION COMPLEX SUBUNIT 3) PROTEIN BINDING
AT5G44635

Predicted

Co-purification

Colocalization

Reconstituted Complex

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

two hybrid

Reconstituted Complex

Synthetic Lethality

in vitro

in vivo

FSW = 0.3670

Unknown

MINICHROMOSOME MAINTENANCE FAMILY PROTEIN / MCM FAMILY PROTEIN
AT2G20980

Predicted

in vivo

in vitro

two hybrid

Affinity Capture-Western

FSW = 0.4235

Unknown

MCM10
AT3G09660

Predicted

Affinity Capture-Western

FSW = 0.1947

Unknown

MCM8 ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE/ NUCLEOSIDE-TRIPHOSPHATASE/ NUCLEOTIDE BINDING
AT2G37840

Predicted

biochemical

FSW = 0.0153

Unknown

PROTEIN KINASE FAMILY PROTEIN
AT3G27000

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0106

Unknown

ARP2 (ACTIN RELATED PROTEIN 2) PROTEIN BINDING / STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT5G22840

Predicted

biochemical

FSW = 0.0179

Unknown

PROTEIN KINASE FAMILY PROTEIN
AT5G46280

Predicted

Colocalization

Colocalization

Affinity Capture-Western

Affinity Capture-Western

Co-expression

FSW = 0.3171

Unknown

DNA REPLICATION LICENSING FACTOR PUTATIVE
AT5G49010

Predicted

Affinity Capture-MS

FSW = 0.1946

Unknown

SLD5 (SYNTHETIC LETHALITY WITH DPB11-1 5)
AT2G07690

Predicted

Affinity Capture-Western

Affinity Capture-Western

FSW = 0.4013

Unknown

MINICHROMOSOME MAINTENANCE FAMILY PROTEIN / MCM FAMILY PROTEIN
AT1G20610

Predicted

Phenotypic Suppression

FSW = 0.0223

Unknown

CYCB23 (CYCLIN B23) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT1G71400

Predicted

Gene fusion method

FSW = 0.0282

Unknown

ATRLP12 (RECEPTOR LIKE PROTEIN 12) PROTEIN BINDING

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454