Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT4G18040 - ( EIF4E (EUKARYOTIC TRANSLATION INITATION FACTOR 4E) RNA binding / RNA cap binding / protein binding / translation initiation factor )
49 Proteins interacs with AT4G18040| Locus | Method | FSW  | Cellular Compartment Classification (C3) | Description |
|---|---|---|---|---|
AT5G22290
   | Experimentalpull down | FSW = 0.0491
| Class A:nucleusClass B:cytosolClass D:cytosol (p = 0.67) | ANAC089 (ARABIDOPSIS NAC DOMAIN CONTAINING PROTEIN 89) TRANSCRIPTION FACTOR |
| AT3G48590
| Experimentalpull down | FSW = 0.0193
| Class A:nucleus | NF-YC1 (NUCLEAR FACTOR Y SUBUNIT C1) DNA BINDING / TRANSCRIPTION ACTIVATOR/ TRANSCRIPTION FACTOR |
| AT3G45140
| ExperimentalReconstituted ComplexCo-purificationAffinity Capture-Westerntwo hybrid | FSW = 0.0513
| Class B:plastidnucleusClass D:cytosol (p = 0.67) | LOX2 (LIPOXYGENASE 2) LIPOXYGENASE |
| AT5G15200
| PredictedAffinity Capture-MS | FSW = 0.0735
| Class C:nucleus | 40S RIBOSOMAL PROTEIN S9 (RPS9B) |
| AT5G20290
| PredictedAffinity Capture-MS | FSW = 0.0888
| Class C:nucleus | 40S RIBOSOMAL PROTEIN S8 (RPS8A) |
| AT3G58510
| Predictedinterologs mappinginterologs mappingSynthetic Lethalityinteraction prediction | FSW = 0.1004
| Class C:nucleus | DEAD BOX RNA HELICASE PUTATIVE (RH11) |
| AT3G11964 | PredictedAffinity Capture-MS | FSW = 0.0465
| Class C:nucleus | RNA BINDING |
| AT2G03870
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0157
| Class C:nucleus | SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE |
| AT5G54840
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0384
| Class C:nucleus | SGP1 GTP BINDING |
| AT2G40290
| PredictedAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0133
| Class C:nucleus | EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 PUTATIVE / EIF-2A PUTATIVE / EIF-2-ALPHA PUTATIVE |
| AT3G13920
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0610
| Class C:nucleus | EIF4A1 (EUKARYOTIC TRANSLATION INITIATION FACTOR 4A1) ATP-DEPENDENT HELICASE/ TRANSLATION INITIATION FACTOR |
| AT4G25630
| PredictedAffinity Capture-MS | FSW = 0.0486
| Class C:nucleus | FIB2 (FIBRILLARIN 2) SNORNA BINDING |
| AT5G44200
| Predictedinteraction prediction | FSW = 0.0504
| Class C:nucleus | CBP20 (CAP-BINDING PROTEIN 20) RNA BINDING / RNA CAP BINDING |
| AT2G18760
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0165
| Class C:nucleus | CHR8 (CHROMATIN REMODELING 8) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING |
| AT2G34720
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0339
| Class C:nucleus | NF-YA4 (NUCLEAR FACTOR Y SUBUNIT A4) SPECIFIC TRANSCRIPTIONAL REPRESSOR/ TRANSCRIPTION FACTOR |
| AT2G17360
| PredictedAffinity Capture-MS | FSW = 0.0599
| Unknown | 40S RIBOSOMAL PROTEIN S4 (RPS4A) |
| AT1G54270
| Predictedinteraction prediction | FSW = 0.0778
| Unknown | EIF4A-2 ATP-DEPENDENT HELICASE/ TRANSLATION INITIATION FACTOR |
| AT1G07770
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0640
| Unknown | RPS15A (RIBOSOMAL PROTEIN S15A) STRUCTURAL CONSTITUENT OF RIBOSOME |
| AT2G29690
| PredictedAffinity Capture-MS | FSW = 0.0349
| Unknown | ASA2 (ANTHRANILATE SYNTHASE 2) ANTHRANILATE SYNTHASE |
| AT5G53460
| Predictedtwo hybridtwo hybrid | FSW = 0.0128
| Unknown | GLT1 GLUTAMATE SYNTHASE (NADH) |
| AT5G05730
| Predictedinteraction prediction | FSW = 0.0385
| Unknown | ASA1 (ANTHRANILATE SYNTHASE ALPHA SUBUNIT 1) ANTHRANILATE SYNTHASE |
| AT1G73180
| Predictedsynthetic growth defect | FSW = 0.0272
| Unknown | EUKARYOTIC TRANSLATION INITIATION FACTOR-RELATED |
| AT3G12050
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0166
| Unknown | AHA1 DOMAIN-CONTAINING PROTEIN |
| AT4G30990
| Predictedinteraction prediction | FSW = 0.0061
| Unknown | BINDING |
| AT5G59240
| PredictedAffinity Capture-MS | FSW = 0.1150
| Unknown | 40S RIBOSOMAL PROTEIN S8 (RPS8B) |
| AT1G35470
| Predictedtwo hybridtwo hybrid | FSW = 0.0308
| Unknown | SPLA/RYANODINE RECEPTOR (SPRY) DOMAIN-CONTAINING PROTEIN |
| AT5G55130
| Predictedtwo hybridtwo hybridCo-expression | FSW = 0.0174
| Unknown | CNX5 (CO-FACTOR FOR NITRATE REDUCTASE AND XANTHINE DEHYDROGENASE 5) MO-MOLYBDOPTERIN COFACTOR SULFURASE |
| AT1G08260
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0224
| Unknown | TIL1 (TILTED 1) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING |
| AT1G09020
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0047
| Unknown | SNF4 (HOMOLOG OF YEAST SUCROSE NONFERMENTING 4) PROTEIN KINASE ACTIVATOR |
| AT1G16350
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0748
| Unknown | INOSINE-5-MONOPHOSPHATE DEHYDROGENASE PUTATIVE |
| AT1G49760
| Predictedinteraction predictionAffinity Capture-MSAffinity Capture-MSSynthetic LethalityCo-expression | FSW = 0.0673
| Unknown | PAB8 (POLY(A) BINDING PROTEIN 8) RNA BINDING / TRANSLATION INITIATION FACTOR |
| AT3G27060
| PredictedSynthetic Lethalityinterologs mapping | FSW = 0.0370
| Unknown | TSO2 (TSO MEANING UGLY IN CHINESE) OXIDOREDUCTASE/ RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE/ TRANSITION METAL ION BINDING |
| AT3G60240
| Predictedinteraction predictionAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSSynthetic LethalitySynthetic LethalityAffinity Capture-WesternReconstituted ComplexAffinity Capture-WesternAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSAffinity Capture-WesternReconstituted Complexfar western blottingSynthetic Lethalitysynthetic growth defectinterologs mapping | FSW = 0.1972
| Unknown | EIF4G (EUKARYOTIC TRANSLATION INITIATION FACTOR 4G) TRANSLATION INITIATION FACTOR |
| AT1G01930
| PredictedAffinity Capture-MS | FSW = 0.0189
| Unknown | ZINC FINGER PROTEIN-RELATED |
| AT2G04520
| PredictedSynthetic Lethality | FSW = 0.0453
| Unknown | EUKARYOTIC TRANSLATION INITIATION FACTOR 1A PUTATIVE / EIF-1A PUTATIVE / EIF-4C PUTATIVE |
| AT2G28360
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0276
| Unknown | INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN ENDOMEMBRANE SYSTEM EXPRESSED IN 22 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S SIT4 PHOSPHATASE-ASSOCIATED PROTEIN (INTERPROIPR007587) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS SIT4 PHOSPHATASE-ASSOCIATED FAMILY PROTEIN (TAIRAT1G079901) HAS 1431 BLAST HITS TO 1107 PROTEINS IN 182 SPECIES ARCHAE - 2 BACTERIA - 108 METAZOA - 552 FUNGI - 305 PLANTS - 89 VIRUSES - 18 OTHER EUKARYOTES - 357 (SOURCE NCBI BLINK) |
| AT3G01160
| PredictedAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0293
| Unknown | UNKNOWN PROTEIN |
| AT3G03340
| PredictedAffinity Capture-MSAffinity Capture-MSinteraction prediction | FSW = 0.0350
| Unknown | UNE6 (UNFERTILIZED EMBRYO SAC 6) |
| AT3G26500
| PredictedAffinity Capture-MSinteraction prediction | FSW = 0.0304
| Unknown | LEUCINE-RICH REPEAT FAMILY PROTEIN |
| AT4G00660
| Predictedsynthetic growth defect | FSW = 0.0603
| Unknown | DEAD/DEAH BOX HELICASE PUTATIVE |
| AT4G30870
| PredictedAffinity Capture-MS | FSW = 0.0143
| Unknown | MUS81 (MMS AND UV SENSITIVE 81) ENDONUCLEASE/ NUCLEIC ACID BINDING |
| AT5G46190
| PredictedAffinity Capture-MSAffinity Capture-MS | FSW = 0.0688
| Unknown | KH DOMAIN-CONTAINING PROTEIN |
| AT5G66100
| PredictedAffinity Capture-MS | FSW = 0.0844
| Unknown | LA DOMAIN-CONTAINING PROTEIN |
| AT4G30991 | PredictedAffinity Capture-MS | FSW = 0.0712
| Unknown | LA DOMAIN-CONTAINING PROTEIN |
| AT4G32720
| PredictedAffinity Capture-MSAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0659
| Unknown | ATLA1 (ARABIDOPSIS THALIANA LA PROTEIN 1) RNA BINDING |
| AT5G10960
| Predictedinterologs mapping | FSW = 0.0321
| Unknown | CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE |
| AT5G04430
| Predictedinteraction prediction | FSW = 0.0606
| Unknown | BTR1L (BINDING TO TOMV RNA 1L (LONG FORM)) NUCLEIC ACID BINDING |
| AT5G39770
| Predictedinteraction prediction | FSW = 0.0110
| Unknown | DNA BINDING / ENDONUCLEASE/ NUCLEASE/ NUCLEIC ACID BINDING / PROTEIN BINDING |
| AT2G27120
| Predictedinteraction prediction | FSW = 0.0439
| Unknown | TIL2 (TILTED 2) DNA BINDING / DNA-DIRECTED DNA POLYMERASE/ NUCLEIC ACID BINDING / NUCLEOTIDE BINDING / ZINC ION BINDING |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
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