Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT2G41630 - ( TFIIB (TRANSCRIPTION FACTOR II B) RNA polymerase II transcription factor/ protein binding / transcription regulator/ translation initiation factor/ zinc ion binding )

72 Proteins interacs with AT2G41630
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT1G35160

Experimental

pull down

FSW = 0.0095

Class A:

nucleus

Class B:

plasma membrane

cytosol

cytoskeleton

Class D:

cytosol (p = 0.67)

GF14 PHI (GF14 PROTEIN PHI CHAIN) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING
AT5G24630

Experimental

two hybrid

FSW = 0.0427

Unknown

BIN4 (BRASSINOSTEROID-INSENSITIVE4) DOUBLE-STRANDED DNA BINDING
AT4G12610

Predicted

Synthetic Rescue

in vitro

Synthetic Rescue

FSW = 0.1917

Class C:

nucleus

TRANSCRIPTION INITIATION FACTOR IIF ALPHA SUBUNIT (TFIIF-ALPHA) FAMILY PROTEIN
AT3G48750

Predicted

Colocalization

FSW = 0.0207

Class C:

nucleus

CDC2 (CELL DIVISION CONTROL 2) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT3G10330

Predicted

Gene fusion method

Phylogenetic profile method

Co-expression

FSW = 0.6184

Class C:

nucleus

TRANSCRIPTION INITIATION FACTOR IIB-2 / GENERAL TRANSCRIPTION FACTOR TFIIB-2 (TFIIB2)
AT5G03720

Predicted

in vitro

FSW = 0.0476

Class C:

nucleus

AT-HSFA3 DNA BINDING / TRANSCRIPTION FACTOR
AT4G10670

Predicted

interologs mapping

FSW = 0.0873

Class C:

nucleus

GTC2
AT5G09860

Predicted

Synthetic Rescue

Synthetic Rescue

FSW = 0.0687

Class C:

nucleus

NUCLEAR MATRIX PROTEIN-RELATED
AT4G31720

Predicted

Affinity Capture-MS

FSW = 0.0316

Class C:

nucleus

TAFII15 (TBP-ASSOCIATED FACTOR II 15) RNA POLYMERASE II TRANSCRIPTION FACTOR/ TRANSCRIPTION FACTOR
AT1G03280

Predicted

in vitro

FSW = 0.0964

Class C:

nucleus

TRANSCRIPTION INITIATION FACTOR IIE (TFIIE) ALPHA SUBUNIT FAMILY PROTEIN / GENERAL TRANSCRIPTION FACTOR TFIIE FAMILY PROTEIN
AT1G44900

Predicted

in vitro

FSW = 0.0251

Class C:

nucleus

ATP BINDING / DNA BINDING / DNA-DEPENDENT ATPASE
AT3G16980

Predicted

Synthetic Rescue

FSW = 0.0858

Class C:

nucleus

NRPB9A DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ NUCLEIC ACID BINDING / TRANSCRIPTION REGULATOR/ ZINC ION BINDING
AT5G07630

Predicted

two hybrid

FSW = 0.0489

Class C:

nucleus

LIPID TRANSPORTER
AT3G55770

Predicted

two hybrid

two hybrid

FSW = 0.0102

Class C:

nucleus

LIM DOMAIN-CONTAINING PROTEIN
AT4G24440

Predicted

Co-crystal Structure

FSW = 0.1162

Class C:

nucleus

TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN / TFIIA-GAMMA (TFIIA-S)
AT1G18340

Predicted

Co-purification

FSW = 0.0845

Class C:

nucleus

BASAL TRANSCRIPTION FACTOR COMPLEX SUBUNIT-RELATED
AT2G34210

Predicted

Affinity Capture-MS

FSW = 0.0639

Class C:

nucleus

STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION INITIATION FACTOR
AT1G55520

Predicted

Reconstituted Complex

Reconstituted Complex

Reconstituted Complex

Reconstituted Complex

interologs mapping

Co-purification

Co-crystal Structure

Co-purification

interologs mapping

in vitro

in vivo

Reconstituted Complex

Synthetic Lethality

Enriched domain pair

Co-expression

FSW = 0.1444

Class C:

nucleus

TBP2 (TATA BINDING PROTEIN 2) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION FACTOR/ TATA-BINDING PROTEIN BINDING
AT1G07470

Predicted

Co-crystal Structure

FSW = 0.0752

Class C:

nucleus

TRANSCRIPTION FACTOR IIA LARGE SUBUNIT PUTATIVE / TFIIA LARGE SUBUNIT PUTATIVE
AT5G59230

Predicted

in vitro

in vivo

FSW = 0.0959

Class C:

nucleus

TRANSCRIPTION FACTOR-RELATED
AT3G29380

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.0789

Class C:

nucleus

TRANSCRIPTION FACTOR IIB (TFIIB) FAMILY PROTEIN
AT1G02130

Predicted

two hybrid

FSW = 0.0074

Unknown

ARA-5 (ARABIDOPSIS RAS 5) GTP BINDING
AT1G01100

Predicted

two hybrid

FSW = 0.0206

Unknown

60S ACIDIC RIBOSOMAL PROTEIN P1 (RPP1A)
AT5G25780

Predicted

Affinity Capture-MS

FSW = 0.0812

Unknown

EIF3B-2 (EUKARYOTIC TRANSLATION INITIATION FACTOR 3B-2) NUCLEIC ACID BINDING / PROTEIN BINDING / TRANSLATION INITIATION FACTOR
AT1G48830

Predicted

two hybrid

FSW = 0.0207

Unknown

40S RIBOSOMAL PROTEIN S7 (RPS7A)
AT3G02660

Predicted

two hybrid

FSW = 0.0279

Unknown

EMB2768 (EMBRYO DEFECTIVE 2768) ATP BINDING / RNA BINDING / AMINOACYL-TRNA LIGASE/ NUCLEOTIDE BINDING / TYROSINE-TRNA LIGASE
AT5G51540

Predicted

two hybrid

FSW = 0.0296

Unknown

METALLOENDOPEPTIDASE
AT4G35800

Predicted

Reconstituted Complex

Co-crystal Structure

Affinity Capture-Western

Co-crystal Structure

Reconstituted Complex

Synthetic Lethality

FSW = 0.1130

Unknown

NRPB1 (RNA POLYMERASE II LARGE SUBUNIT) DNA BINDING / DNA-DIRECTED RNA POLYMERASE
AT2G36390

Predicted

two hybrid

FSW = 0.0677

Unknown

SBE21 (STARCH BRANCHING ENZYME 21) 14-ALPHA-GLUCAN BRANCHING ENZYME
AT5G53460

Predicted

Affinity Capture-MS

FSW = 0.0320

Unknown

GLT1 GLUTAMATE SYNTHASE (NADH)
AT1G73820

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Affinity Capture-Western

interologs mapping

Reconstituted Complex

Synthetic Lethality

FSW = 0.0480

Unknown

SSU72-LIKE FAMILY PROTEIN
AT1G80380

Predicted

two hybrid

FSW = 0.0356

Unknown

PHOSPHORIBULOKINASE/URIDINE KINASE-RELATED
AT1G53750

Predicted

in vitro

in vivo

FSW = 0.0188

Unknown

RPT1A (REGULATORY PARTICLE TRIPLE-A 1A) ATPASE
AT2G19480

Predicted

Reconstituted Complex

FSW = 0.0267

Unknown

NAP12 (NUCLEOSOME ASSEMBLY PROTEIN 12) DNA BINDING
AT1G50480

Predicted

two hybrid

FSW = 0.0206

Unknown

THFS (10-FORMYLTETRAHYDROFOLATE SYNTHETASE) ATP BINDING / COPPER ION BINDING / FORMATE-TETRAHYDROFOLATE LIGASE
AT4G11420

Predicted

Affinity Capture-MS

FSW = 0.0400

Unknown

EIF3A (EUKARYOTIC TRANSLATION INITIATION FACTOR 3A) TRANSLATION INITIATION FACTOR
AT2G18040

Predicted

two hybrid

FSW = 0.0617

Unknown

PIN1AT (PEPTIDYLPROLYL CIS/TRANS ISOMERASE NIMA-INTERACTING 1) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
AT3G11400

Predicted

Affinity Capture-MS

FSW = 0.0687

Unknown

EUKARYOTIC TRANSLATION INITIATION FACTOR 3G / EIF3G
AT5G19180

Predicted

two hybrid

FSW = 0.0163

Unknown

ECR1 (E1 C-TERMINAL RELATED 1) NEDD8 ACTIVATING ENZYME/ PROTEIN HETERODIMERIZATION/ SMALL PROTEIN ACTIVATING ENZYME
AT1G75510

Predicted

Co-purification

two hybrid

FSW = 0.0914

Unknown

TRANSCRIPTION INITIATION FACTOR IIF BETA SUBUNIT (TFIIF-BETA) FAMILY PROTEIN
AT5G43430

Predicted

two hybrid

FSW = 0.0142

Unknown

ETFBETA ELECTRON CARRIER
AT1G01310

Predicted

two hybrid

FSW = 0.0125

Unknown

ALLERGEN V5/TPX-1-RELATED FAMILY PROTEIN
AT2G35630

Predicted

two hybrid

FSW = 0.0534

Unknown

MOR1 (MICROTUBULE ORGANIZATION 1) MICROTUBULE BINDING
AT1G48160

Predicted

two hybrid

FSW = 0.0163

Unknown

SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN PUTATIVE / SRP19 PUTATIVE
AT3G12530

Predicted

two hybrid

FSW = 0.0036

Unknown

PSF2
AT2G46470

Predicted

two hybrid

FSW = 0.0226

Unknown

OXA1L (INNER MEMBRANE PROTEIN OXA1-LIKE)
AT4G21710

Predicted

Phenotypic Suppression

synthetic growth defect

FSW = 0.1065

Unknown

NRPB2 DNA BINDING / DNA-DIRECTED RNA POLYMERASE
AT4G28820

Predicted

two hybrid

two hybrid

FSW = 0.0296

Unknown

ZINC FINGER (HIT TYPE) FAMILY PROTEIN
AT3G22860

Predicted

Affinity Capture-MS

FSW = 0.0480

Unknown

TIF3C2 TRANSLATION INITIATION FACTOR
AT2G46280

Predicted

Affinity Capture-MS

FSW = 0.0520

Unknown

TRIP-1 (TGF-BETA RECEPTOR INTERACTING PROTEIN 1) NUCLEOTIDE BINDING / PROTEIN BINDING
AT1G36730

Predicted

Affinity Capture-MS

FSW = 0.0941

Unknown

EUKARYOTIC TRANSLATION INITIATION FACTOR 5 PUTATIVE / EIF-5 PUTATIVE
AT2G10440

Predicted

Affinity Capture-Western

FSW = 0.0608

Unknown

UNKNOWN PROTEIN
AT3G22590

Predicted

Co-purification

two hybrid

FSW = 0.0482

Unknown

RNA POL II ACCESSORY FACTOR CDC73 FAMILY PROTEIN
AT5G18230

Predicted

interologs mapping

FSW = 0.0434

Unknown

TRANSCRIPTION REGULATOR NOT2/NOT3/NOT5 FAMILY PROTEIN
AT4G20330

Predicted

in vitro

in vitro

Co-expression

FSW = 0.1340

Unknown

TRANSCRIPTION INITIATION FACTOR-RELATED
AT1G20320

Predicted

Reconstituted Complex

FSW = 0.1216

Unknown

NLI INTERACTING FACTOR (NIF) FAMILY PROTEIN
AT1G26170Predicted

Reconstituted Complex

FSW = 0.0583

Unknown

BINDING / PROTEIN TRANSPORTER
AT3G27000

Predicted

Synthetic Lethality

FSW = 0.0075

Unknown

ARP2 (ACTIN RELATED PROTEIN 2) PROTEIN BINDING / STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT3G49660

Predicted

two hybrid

FSW = 0.0171

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT1G55255Predicted

two hybrid

FSW = 0.0046

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT2G03430

Predicted

two hybrid

FSW = 0.0189

Unknown

ANKYRIN REPEAT FAMILY PROTEIN
AT3G21350

Predicted

two hybrid

FSW = 0.0233

Unknown

RNA POLYMERASE TRANSCRIPTIONAL REGULATION MEDIATOR-RELATED
AT5G17410

Predicted

two hybrid

FSW = 0.0482

Unknown

TUBULIN FAMILY PROTEIN
AT1G13180

Predicted

two hybrid

FSW = 0.0189

Unknown

DIS1 (DISTORTED TRICHOMES 1) ATP BINDING / ACTIN BINDING / PROTEIN BINDING / STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT3G09670

Predicted

two hybrid

FSW = 0.0107

Unknown

PWWP DOMAIN-CONTAINING PROTEIN
AT3G20790

Predicted

two hybrid

FSW = 0.0137

Unknown

OXIDOREDUCTASE FAMILY PROTEIN
AT2G45730

Predicted

two hybrid

FSW = 0.0711

Unknown

EUKARYOTIC INITIATION FACTOR 3 GAMMA SUBUNIT FAMILY PROTEIN
AT3G20800

Predicted

two hybrid

FSW = 0.0185

Unknown

RCD1-LIKE CELL DIFFERENTIATION PROTEIN PUTATIVE
AT2G16370

Predicted

two hybrid

FSW = 0.0237

Unknown

THY-1 (THYMIDYLATE SYNTHASE 1) DIHYDROFOLATE REDUCTASE/ THYMIDYLATE SYNTHASE
AT1G22882

Predicted

two hybrid

FSW = 0.0427

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN MITOCHONDRION CONTAINS INTERPRO DOMAIN/S SAD1/UNC-LIKE C-TERMINAL (INTERPROIPR012919) GALACTOSE-BINDING LIKE (INTERPROIPR008979) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT1G713601) HAS 1862 BLAST HITS TO 1619 PROTEINS IN 245 SPECIES ARCHAE - 32 BACTERIA - 119 METAZOA - 736 FUNGI - 195 PLANTS - 90 VIRUSES - 21 OTHER EUKARYOTES - 669 (SOURCE NCBI BLINK)
AT4G27040

Predicted

two hybrid

FSW = 0.0139

Unknown

VPS22
AT5G52210

Predicted

two hybrid

FSW = 0.0083

Unknown

ATGB1 (ARABIDOPSIS THALIANA GTP-BINDING PROTEIN 1) GTP BINDING

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454