Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT1G78900 - ( VHA-A (VACUOLAR ATP SYNTHASE SUBUNIT A) ATP binding / hydrogen ion transporting ATP synthase rotational mechanism / hydrolase acting on acid anhydrides catalyzing transmembrane movement of substances / proton-transporting ATPase rotational mechanism )

62 Proteins interacs with AT1G78900
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G48750

Experimental

Affinity Capture-MS

affinity technology

FSW = 0.0122

Class A:

plasma membrane

Class B:

vacuole

plastid

nucleus

cytosol

Class D:

cytosol (p = 0.67)

CDC2 (CELL DIVISION CONTROL 2) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT5G35410

Experimental

interaction detection method

FSW = 0.0509

Unknown

SOS2 (SALT OVERLY SENSITIVE 2) KINASE/ PROTEIN KINASE
AT5G08670

Predicted

Affinity Capture-MS

FSW = 0.0368

Class C:

vacuole

plastid

plasma membrane

ATP BINDING / HYDROGEN ION TRANSPORTING ATP SYNTHASE ROTATIONAL MECHANISM
AT3G42050

Predicted

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Co-expression

FSW = 0.2180

Class C:

vacuole

plastid

plasma membrane

VACUOLAR ATP SYNTHASE SUBUNIT H FAMILY PROTEIN
AT1G76030

Predicted

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

co-fractionation

Co-fractionation

Affinity Capture-Western

two hybrid

co-fractionation

Co-fractionation

Affinity Capture-MS

interaction prediction

Enriched domain pair

Gene neighbors method

FSW = 0.1711

Class C:

vacuole

plastid

plasma membrane

VACUOLAR ATP SYNTHASE SUBUNIT B / V-ATPASE B SUBUNIT / VACUOLAR PROTON PUMP B SUBUNIT / V-ATPASE 57 KDA SUBUNIT
AT2G21410

Predicted

two hybrid

co-fractionation

Co-fractionation

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

two hybrid

two hybrid

Affinity Capture-Western

co-fractionation

Co-fractionation

Affinity Capture-MS

interaction prediction

FSW = 0.2885

Class C:

vacuole

plastid

VHA-A2 (VACUOLAR PROTON ATPASE A2) ATPASE
AT1G20260

Predicted

co-fractionation

Co-fractionation

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Co-fractionation

two hybrid

Enriched domain pair

Gene neighbors method

FSW = 0.0821

Class C:

vacuole

plastid

HYDROGEN ION TRANSPORTING ATP SYNTHASE ROTATIONAL MECHANISM / HYDROLASE ACTING ON ACID ANHYDRIDES CATALYZING TRANSMEMBRANE MOVEMENT OF SUBSTANCES / PROTON-TRANSPORTING ATPASE ROTATIONAL MECHANISM
AT1G12840

Predicted

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.1607

Class C:

vacuole

plasma membrane

DET3 (DE-ETIOLATED 3) PROTON-TRANSPORTING ATPASE ROTATIONAL MECHANISM
AT3G01390

Predicted

Affinity Capture-MS

Affinity Capture-Western

co-fractionation

Co-fractionation

FSW = 0.1667

Class C:

vacuole

plasma membrane

VMA10 (VACUOLAR MEMBRANE ATPASE 10) HYDROGEN ION TRANSPORTING ATP SYNTHASE ROTATIONAL MECHANISM
AT4G02620

Predicted

co-fractionation

Co-fractionation

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

co-fractionation

Co-fractionation

interaction prediction

FSW = 0.2404

Class C:

vacuole

plasma membrane

VACUOLAR ATPASE SUBUNIT F FAMILY PROTEIN
AT3G58730

Predicted

co-fractionation

Co-fractionation

co-fractionation

Co-fractionation

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

co-fractionation

Co-fractionation

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

co-fractionation

Co-fractionation

interaction prediction

Co-expression

FSW = 0.2400

Class C:

vacuole

plasma membrane

VACUOLAR ATP SYNTHASE SUBUNIT D (VATD) / V-ATPASE D SUBUNIT / VACUOLAR PROTON PUMP D SUBUNIT (VATPD)
AT3G28715

Predicted

Affinity Capture-Western

FSW = 0.0637

Class C:

vacuole

plasma membrane

H+-TRANSPORTING TWO-SECTOR ATPASE PUTATIVE
AT3G28710

Predicted

Affinity Capture-Western

FSW = 0.0616

Class C:

vacuole

plasma membrane

H+-TRANSPORTING TWO-SECTOR ATPASE PUTATIVE
AT1G19910

Predicted

Affinity Capture-Western

FSW = 0.0182

Class C:

vacuole

plasma membrane

AVA-P2 ATPASE/ PROTON-TRANSPORTING ATPASE ROTATIONAL MECHANISM
AT4G17140Predicted

Affinity Capture-MS

FSW = 0.0287

Class C:

vacuole

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN VACUOLE EXPRESSED IN 24 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S PLECKSTRIN HOMOLOGY (INTERPROIPR001849) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS PHOSPHOINOSITIDE BINDING (TAIRAT1G480902) HAS 1924 BLAST HITS TO 1182 PROTEINS IN 161 SPECIES ARCHAE - 0 BACTERIA - 16 METAZOA - 911 FUNGI - 304 PLANTS - 271 VIRUSES - 0 OTHER EUKARYOTES - 422 (SOURCE NCBI BLINK)
AT2G46560

Predicted

Affinity Capture-Western

Affinity Capture-MS

FSW = 0.1717

Class C:

vacuole

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT1G64200

Predicted

Affinity Capture-MS

Affinity Capture-Western

co-fractionation

Co-fractionation

FSW = 0.2616

Class C:

vacuole

VHA-E3 (VACUOLAR H+-ATPASE SUBUNIT E ISOFORM 3) PROTON-TRANSPORTING ATPASE ROTATIONAL MECHANISM
AT2G43750

Predicted

Synthetic Rescue

FSW = 0.0652

Class C:

plastid

OASB (O-ACETYLSERINE (THIOL) LYASE B) CYSTEINE SYNTHASE
AT3G59760

Predicted

interaction prediction

FSW = 0.0329

Class C:

plastid

OASC (O-ACETYLSERINE (THIOL) LYASE ISOFORM C) ATP BINDING / CYSTEINE SYNTHASE
AT1G48090Predicted

Affinity Capture-MS

FSW = 0.0287

Class C:

plastid

PHOSPHOINOSITIDE BINDING
AT1G11890

Predicted

Phenotypic Enhancement

FSW = 0.0256

Class C:

plasma membrane

SEC22 TRANSPORTER
AT5G04990

Predicted

two hybrid

two hybrid

FSW = 0.0077

Unknown

SAD1/UNC-84 PROTEIN-RELATED
AT5G37720

Predicted

Affinity Capture-MS

FSW = 0.0104

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT1G20140

Predicted

Affinity Capture-Western

FSW = 0.0307

Unknown

ASK4 (ARABIDOPSIS SKP1-LIKE 4) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT1G03190

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0698

Unknown

UVH6 (ULTRAVIOLET HYPERSENSITIVE 6) ATP BINDING / ATP-DEPENDENT DNA HELICASE/ ATP-DEPENDENT HELICASE/ DNA BINDING / HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING
AT4G14540

Predicted

interaction prediction

FSW = 0.0335

Unknown

NF-YB3 (NUCLEAR FACTOR Y SUBUNIT B3) TRANSCRIPTION FACTOR
AT2G18760

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0201

Unknown

CHR8 (CHROMATIN REMODELING 8) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT5G47640

Predicted

Affinity Capture-MS

FSW = 0.0321

Unknown

NF-YB2 (NUCLEAR FACTOR Y SUBUNIT B2) TRANSCRIPTION FACTOR
AT2G13570

Predicted

Affinity Capture-MS

FSW = 0.0345

Unknown

NF-YB7 (NUCLEAR FACTOR Y SUBUNIT B7) TRANSCRIPTION FACTOR
AT3G11460

Predicted

Gene fusion method

FSW = 0.0205

Unknown

PENTATRICOPEPTIDE (PPR) REPEAT-CONTAINING PROTEIN
AT2G31970

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0239

Unknown

RAD50 ATP BINDING / NUCLEASE/ ZINC ION BINDING
AT1G79750

Predicted

Affinity Capture-MS

FSW = 0.0216

Unknown

ATNADP-ME4 (NADP-MALIC ENZYME 4) MALATE DEHYDROGENASE (OXALOACETATE-DECARBOXYLATING) (NADP+)/ MALIC ENZYME/ OXIDOREDUCTASE ACTING ON NADH OR NADPH NAD OR NADP AS ACCEPTOR
AT3G05210

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0377

Unknown

ERCC1 5-FLAP ENDONUCLEASE
AT2G12550

Predicted

two hybrid

two hybrid

FSW = 0.0117

Unknown

UBIQUITIN-ASSOCIATED (UBA)/TS-N DOMAIN-CONTAINING PROTEIN
AT1G64550

Predicted

Affinity Capture-MS

FSW = 0.0401

Unknown

ATGCN3 TRANSPORTER
AT1G08780

Predicted

Affinity Capture-MS

FSW = 0.0454

Unknown

AIP3 (ABI3-INTERACTING PROTEIN 3) UNFOLDED PROTEIN BINDING
AT1G29990

Predicted

Phenotypic Enhancement

FSW = 0.0392

Unknown

PDF6 (PREFOLDIN 6) UNFOLDED PROTEIN BINDING
AT1G30580

Predicted

Affinity Capture-MS

FSW = 0.0130

Unknown

GTP BINDING
AT1G60620

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0213

Unknown

ATRPAC43 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION
AT2G32600

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0233

Unknown

HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY PROTEIN
AT3G08560

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

co-fractionation

Co-fractionation

FSW = 0.2404

Unknown

VHA-E2 (VACUOLAR H+-ATPASE SUBUNIT E ISOFORM 2) HYDROGEN-EXPORTING ATPASE PHOSPHORYLATIVE MECHANISM / PROTON-TRANSPORTING ATPASE ROTATIONAL MECHANISM
AT3G18860

Predicted

Phenotypic Enhancement

FSW = 0.0203

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G22142

Predicted

Affinity Capture-MS

FSW = 0.0918

Unknown

STRUCTURAL CONSTITUENT OF CELL WALL
AT3G22480

Predicted

Phenotypic Enhancement

FSW = 0.0417

Unknown

PREFOLDIN-RELATED KE2 FAMILY PROTEIN
AT3G53570

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0117

Unknown

AFC1 (ARABIDOPSIS FUS3-COMPLEMENTING GENE 1) ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT3G58560

Predicted

synthetic growth defect

FSW = 0.0249

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT5G08560

Predicted

Affinity Capture-MS

FSW = 0.0137

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT5G10260

Predicted

Phenotypic Enhancement

FSW = 0.0463

Unknown

ATRABH1E (ARABIDOPSIS RAB GTPASE HOMOLOG H1E) GTP BINDING
AT5G10960

Predicted

Affinity Capture-MS

synthetic growth defect

FSW = 0.0262

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT5G14050

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0091

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT5G16750

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0110

Unknown

TOZ (TORMOZEMBRYO DEFECTIVE) NUCLEOTIDE BINDING
AT5G42190

Predicted

Affinity Capture-Western

interaction prediction

FSW = 0.0191

Unknown

ASK2 (ARABIDOPSIS SKP1-LIKE 2) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT5G44635

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0045

Unknown

MINICHROMOSOME MAINTENANCE FAMILY PROTEIN / MCM FAMILY PROTEIN
AT5G48120

Predicted

Affinity Capture-MS

FSW = 0.0721

Unknown

BINDING
AT5G63140

Predicted

Synthetic Lethality

FSW = 0.0330

Unknown

ATPAP29 (ARABIDOPSIS THALIANA PURPLE ACID PHOSPHATASE 29) ACID PHOSPHATASE/ PROTEIN SERINE/THREONINE PHOSPHATASE
AT5G67320

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0685

Unknown

HOS15 (HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 15)
AT5G02530

Predicted

Affinity Capture-MS

FSW = 0.0126

Unknown

RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE
AT1G53570

Predicted

Affinity Capture-MS

interaction prediction

FSW = 0.0107

Unknown

MAP3KA ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT5G17270

Predicted

Affinity Capture-MS

FSW = 0.0345

Unknown

TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN
AT1G15920

Predicted

Affinity Capture-MS

synthetic growth defect

FSW = 0.0217

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE
AT1G14230

Predicted

interologs mapping

FSW = 0.0364

Unknown

NUCLEOSIDE PHOSPHATASE FAMILY PROTEIN / GDA1/CD39 FAMILY PROTEIN
AT2G32070

Predicted

interaction prediction

FSW = 0.0566

Unknown

CCR4-NOT TRANSCRIPTION COMPLEX PROTEIN PUTATIVE

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454