Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT3G60360 - ( EDA14 (EMBRYO SAC DEVELOPMENT ARREST 14) )
70 Proteins interacs with AT3G60360| Locus | Method | FSW  | Cellular Compartment Classification (C3) | Description |
|---|---|---|---|---|
AT5G09590
   | PredictedSynthetic LethalityPhenotypic Enhancement | FSW = 0.1319
| Unknown | MTHSC70-2 (MITOCHONDRIAL HSP70 2) ATP BINDING |
| AT5G10350
| PredictedAffinity Capture-MS | FSW = 0.2005
| Unknown | POLYADENYLATE-BINDING PROTEIN FAMILY PROTEIN / PABP FAMILY PROTEIN |
| AT5G13450
| PredictedSynthetic Lethality | FSW = 0.1263
| Unknown | ATP SYNTHASE DELTA CHAIN MITOCHONDRIAL PUTATIVE / H(+)-TRANSPORTING TWO-SECTOR ATPASE DELTA (OSCP) SUBUNIT PUTATIVE |
| AT5G65430
| PredictedPhenotypic Enhancement | FSW = 0.1004
| Unknown | GRF8 (GENERAL REGULATORY FACTOR 8) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING |
| AT1G22170
| Predictedsynthetic growth defect | FSW = 0.1610
| Unknown | PHOSPHOGLYCERATE/BISPHOSPHOGLYCERATE MUTASE FAMILY PROTEIN |
| AT1G51040
| PredictedAffinity Capture-MS | FSW = 0.0173
| Unknown | PHOSPHATIDYLINOSITOL 4-KINASE PUTATIVE |
| AT5G60540
| PredictedSynthetic Lethality | FSW = 0.3272
| Unknown | PDX2 (PYRIDOXINE BIOSYNTHESIS 2) GLUTAMINASE/ GLUTAMINYL-TRNA SYNTHASE (GLUTAMINE-HYDROLYZING)/ PROTEIN HETERODIMERIZATION |
| AT1G11680
| PredictedSynthetic Lethality | FSW = 0.0157
| Unknown | CYP51G1 (CYTOCHROME P450 51G1) OXYGEN BINDING / STEROL 14-DEMETHYLASE |
| AT4G36490
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MS | FSW = 0.2021
| Unknown | SFH12 (SEC14-LIKE 12) PHOSPHATIDYLINOSITOL TRANSPORTER/ TRANSPORTER |
| AT2G32670
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSPhenotypic Enhancement | FSW = 0.4213
| Unknown | ATVAMP725 |
| AT1G04750
| PredictedSynthetic Lethality | FSW = 0.1752
| Unknown | VAMP721 (VESICLE-ASSOCIATED MEMBRANE PROTEIN 721) |
| AT2G30110
| PredictedAffinity Capture-MS | FSW = 0.0056
| Unknown | ATUBA1 UBIQUITIN ACTIVATING ENZYME/ UBIQUITIN-PROTEIN LIGASE |
| AT4G33090
| PredictedSynthetic Lethality | FSW = 0.1103
| Unknown | APM1 (AMINOPEPTIDASE M1) AMINOPEPTIDASE |
| AT2G37790
| Predictedsynthetic growth defect | FSW = 0.3167
| Unknown | ALDO/KETO REDUCTASE FAMILY PROTEIN |
| AT1G80050
| PredictedPhenotypic Suppression | FSW = 0.2295
| Unknown | APT2 (ADENINE PHOSPHORIBOSYL TRANSFERASE 2) ADENINE PHOSPHORIBOSYLTRANSFERASE/ PHOSPHATE TRANSMEMBRANE TRANSPORTER |
| AT5G48880
| PredictedSynthetic Lethality | FSW = 0.0534
| Unknown | PKT2 (PEROXISOMAL 3-KETO-ACYL-COA THIOLASE 2) ACETYL-COA C-ACYLTRANSFERASE/ CATALYTIC |
| AT3G04460
| PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.1509
| Unknown | PEX12 PROTEIN BINDING / ZINC ION BINDING |
| AT4G25630
| PredictedSynthetic LethalityCo-expression | FSW = 0.0135
| Unknown | FIB2 (FIBRILLARIN 2) SNORNA BINDING |
| AT3G52250
| PredictedSynthetic Lethality | FSW = 0.1342
| Unknown | DNA BINDING / TRANSCRIPTION FACTOR |
| AT3G13445
| PredictedPhenotypic Enhancement | FSW = 0.1165
| Unknown | TBP1 (TATA BINDING PROTEIN 1) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION FACTOR/ BINDING |
| AT5G05210
| Predictedtwo hybrid | FSW = 0.0256
| Unknown | NUCLEOLAR MATRIX PROTEIN-RELATED |
| AT3G05060
| PredictedAffinity Capture-MSCo-expression | FSW = 0.0178
| Unknown | SAR DNA-BINDING PROTEIN PUTATIVE |
| AT2G40290
| PredictedAffinity Capture-MS | FSW = 0.0348
| Unknown | EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 PUTATIVE / EIF-2A PUTATIVE / EIF-2-ALPHA PUTATIVE |
| AT4G25340
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSSynthetic LethalityAffinity Capture-MSSynthetic Lethality | FSW = 0.3344
| Unknown | IMMUNOPHILIN-RELATED / FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED |
| AT5G66540
| PredictedAffinity Capture-MSCo-expression | FSW = 0.0271
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN RRNA PROCESSING LOCATED IN CYTOSOL NUCLEOLUS NUCLEUS EXPRESSED IN 22 PLANT STRUCTURES EXPRESSED DURING 12 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEX SUBUNIT MPP10P (INTERPROIPR012173) MPP10 PROTEIN (INTERPROIPR007151) HAS 76240 BLAST HITS TO 38667 PROTEINS IN 1479 SPECIES ARCHAE - 252 BACTERIA - 6537 METAZOA - 31185 FUNGI - 9935 PLANTS - 3937 VIRUSES - 750 OTHER EUKARYOTES - 23644 (SOURCE NCBI BLINK) |
| AT5G60980
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSSynthetic Lethality | FSW = 0.1635
| Unknown | NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN / RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN |
| AT2G30160
| PredictedSynthetic LethalitySynthetic LethalityPhenotypic Enhancement | FSW = 0.2312
| Unknown | MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN |
| AT3G18480
| PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.2146
| Unknown | ATCASP (ARABIDOPSIS THALIANA CCAAT-DISPLACEMENT PROTEIN ALTERNATIVELY SPLICED PRODUCT) |
| AT5G24090
| PredictedSynthetic Lethality | FSW = 0.1006
| Unknown | ACIDIC ENDOCHITINASE (CHIB1) |
| AT4G39200
| PredictedSynthetic LethalitySynthetic LethalityPhenotypic Enhancementsynthetic growth defect | FSW = 0.2994
| Unknown | 40S RIBOSOMAL PROTEIN S25 (RPS25E) |
| AT4G16420
| PredictedSynthetic LethalitySynthetic LethalityPhenotypic Enhancement | FSW = 0.1831
| Unknown | ADA2B (HOMOLOG OF YEAST ADA2 2B) DNA BINDING / TRANSCRIPTION COACTIVATOR/ TRANSCRIPTION FACTOR |
| AT2G29540
| PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.1245
| Unknown | ATRPC14 (RNA POLYMERASE 14 KDA SUBUNIT) DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION |
| AT4G17190
| PredictedAffinity Capture-MS | FSW = 0.1052
| Unknown | FPS2 (FARNESYL DIPHOSPHATE SYNTHASE 2) DIMETHYLALLYLTRANSTRANSFERASE/ GERANYLTRANSTRANSFERASE |
| AT3G12280
| PredictedPhenotypic Enhancement | FSW = 0.0029
| Unknown | RBR1 (RETINOBLASTOMA-RELATED 1) TRANSCRIPTION FACTOR BINDING |
| AT1G13580
| PredictedSynthetic Lethality | FSW = 0.2869
| Unknown | LAG13 (LAG1 LONGEVITY ASSURANCE HOMOLOG 3) |
| AT1G20693
| PredictedPhenotypic Suppression | FSW = 0.3016
| Unknown | HMGB2 (HIGH MOBILITY GROUP B 2) DNA BINDING / CHROMATIN BINDING / STRUCTURAL CONSTITUENT OF CHROMATIN / TRANSCRIPTION FACTOR |
| AT1G29970
| PredictedAffinity Capture-MSAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-Western | FSW = 0.3241
| Unknown | RPL18AA (60S RIBOSOMAL PROTEIN L18A-1) |
| AT1G30580
| Predictedinterologs mapping | FSW = 0.0053
| Unknown | GTP BINDING |
| AT1G34580
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MS | FSW = 0.1036
| Unknown | MONOSACCHARIDE TRANSPORTER PUTATIVE |
| AT2G33560
| Predictedsynthetic growth defect | FSW = 0.0542
| Unknown | SPINDLE CHECKPOINT PROTEIN-RELATED |
| AT2G37420
| PredictedSynthetic LethalitySynthetic LethalityPhenotypic Enhancement | FSW = 0.3210
| Unknown | KINESIN MOTOR PROTEIN-RELATED |
| AT3G02000
| PredictedPhenotypic Enhancement | FSW = 0.1361
| Unknown | ROXY1 DISULFIDE OXIDOREDUCTASE |
| AT3G06483
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-WesternAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-Westernco-fractionationCo-fractionationSynthetic Rescue | FSW = 0.3149
| Unknown | PDK (PYRUVATE DEHYDROGENASE KINASE) ATP BINDING / HISTIDINE PHOSPHOTRANSFER KINASE/ PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE |
| AT3G11230
| Predictedsynthetic growth defect | FSW = 0.3580
| Unknown | YIPPEE FAMILY PROTEIN |
| AT3G18660
| PredictedSynthetic Lethality | FSW = 0.0935
| Unknown | PGSIP1 (PLANT GLYCOGENIN-LIKE STARCH INITIATION PROTEIN 1) TRANSFERASE TRANSFERRING GLYCOSYL GROUPS |
| AT3G21460
| PredictedSynthetic LethalitySynthetic Lethalitysynthetic growth defect | FSW = 0.1684
| Unknown | ELECTRON CARRIER/ PROTEIN DISULFIDE OXIDOREDUCTASE |
| AT3G48150
| PredictedSynthetic Lethality | FSW = 0.0174
| Unknown | APC8 (ANAPHASE-PROMOTING COMPLEX SUBUNIT 8) BINDING |
| AT1G10280
| PredictedPhenotypic Enhancement | FSW = 0.0718
| Unknown | UNKNOWN PROTEIN |
| AT1G11510
| Predictedsynthetic growth defect | FSW = 0.1911
| Unknown | DNA-BINDING STOREKEEPER PROTEIN-RELATED |
| AT1G15440
| PredictedAffinity Capture-MSAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0408
| Unknown | TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN |
| AT1G35350
| PredictedSynthetic Lethality | FSW = 0.1152
| Unknown | LOCATED IN INTEGRAL TO MEMBRANE EXPRESSED IN 18 PLANT STRUCTURES EXPRESSED DURING 9 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S EXS C-TERMINAL (INTERPROIPR004342) SPX N-TERMINAL (INTERPROIPR004331) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS EXS FAMILY PROTEIN / ERD1/XPR1/SYG1 FAMILY PROTEIN (TAIRAT1G267301) HAS 734 BLAST HITS TO 697 PROTEINS IN 158 SPECIES ARCHAE - 0 BACTERIA - 21 METAZOA - 234 FUNGI - 245 PLANTS - 125 VIRUSES - 0 OTHER EUKARYOTES - 109 (SOURCE NCBI BLINK) |
| AT1G55300
| PredictedPhenotypic Enhancement | FSW = 0.2173
| Unknown | TAF7 (TBP-ASSOCIATED FACTOR 7) GENERAL RNA POLYMERASE II TRANSCRIPTION FACTOR |
| AT1G74810
| PredictedSynthetic Lethality | FSW = 0.0263
| Unknown | BOR5 ANION EXCHANGER |
| AT2G48100
| PredictedPhenotypic Suppression | FSW = 0.1476
| Unknown | EXONUCLEASE FAMILY PROTEIN |
| AT3G13210
| PredictedSynthetic Lethalitysynthetic growth defectPhenotypic Enhancement | FSW = 0.1933
| Unknown | CROOKED NECK PROTEIN PUTATIVE / CELL CYCLE PROTEIN PUTATIVE |
| AT3G47610
| Predictedsynthetic growth defect | FSW = 0.0723
| Unknown | TRANSCRIPTION REGULATOR/ ZINC ION BINDING |
| AT4G04700
| PredictedSynthetic RescueSynthetic Rescue | FSW = 0.0639
| Unknown | CPK27 ATP BINDING / CALCIUM ION BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE/ PROTEIN TYROSINE KINASE |
| AT4G14710
| PredictedSynthetic Lethality | FSW = 0.1703
| Unknown | ACIREDUCTONE DIOXYGENASE [IRON(II)-REQUIRING]/ METAL ION BINDING |
| AT4G27130
| PredictedSynthetic Lethalitysynthetic growth defect | FSW = 0.2440
| Unknown | EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 PUTATIVE |
| AT4G29580
| PredictedPhenotypic Enhancement | FSW = 0.0375
| Unknown | CYTIDINE DEAMINASE PUTATIVE / CYTIDINE AMINOHYDROLASE PUTATIVE |
| AT5G14050
| PredictedAffinity Capture-MSinteraction predictionCo-expression | FSW = 0.0212
| Unknown | TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN |
| AT5G14060
| PredictedSynthetic LethalitySynthetic LethalitySynthetic LethalityPhenotypic Enhancement | FSW = 0.2254
| Unknown | CARAB-AK-LYS AMINO ACID BINDING / ASPARTATE KINASE |
| AT5G14180
| PredictedSynthetic LethalitySynthetic LethalitySynthetic Lethality | FSW = 0.3314
| Unknown | MPL1 (MYZUS PERSICAE-INDUCED LIPASE 1) CATALYTIC |
| AT5G42720
| Predictedsynthetic growth defect | FSW = 0.1610
| Unknown | GLYCOSYL HYDROLASE FAMILY 17 PROTEIN |
| AT5G54940
| Predictedsynthetic growth defect | FSW = 0.2044
| Unknown | EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 PUTATIVE |
| AT5G67540
| PredictedSynthetic LethalitySynthetic Lethality | FSW = 0.1981
| Unknown | GLYCOSYL HYDROLASE FAMILY PROTEIN 43 |
| AT5G01430
| PredictedAffinity Capture-MS | FSW = 0.2041
| Unknown | GOT1-LIKE FAMILY PROTEIN |
| AT5G06600
| PredictedAffinity Capture-MS | FSW = 0.1545
| Unknown | UBP12 (UBIQUITIN-SPECIFIC PROTEASE 12) UBIQUITIN THIOLESTERASE/ UBIQUITIN-SPECIFIC PROTEASE |
| AT5G44830
| PredictedSynthetic Lethality | FSW = 0.2382
| Unknown | GLYCOSIDE HYDROLASE FAMILY 28 PROTEIN / POLYGALACTURONASE (PECTINASE) FAMILY PROTEIN |
| AT5G64760
| PredictedPhenotypic Enhancement | FSW = 0.2152
| Unknown | RPN5B (REGULATORY PARTICLE NON-ATPASE SUBUNIT 5B) |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
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