Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT1G62800 - ( ASP4 (ASPARTATE AMINOTRANSFERASE 4) catalytic/ pyridoxal phosphate binding / transaminase/ transferase transferring nitrogenous groups )

72 Proteins interacs with AT1G62800
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G47520

Predicted

Synthetic Rescue

Phenotypic Enhancement

Synthetic Rescue

Phenotypic Enhancement

Synthetic Rescue

FSW = 0.0810

Unknown

MDH (MALATE DEHYDROGENASE) L-MALATE DEHYDROGENASE/ BINDING / CATALYTIC/ MALATE DEHYDROGENASE/ OXIDOREDUCTASE/ OXIDOREDUCTASE ACTING ON THE CH-OH GROUP OF DONORS NAD OR NADP AS ACCEPTOR
AT5G09590

Predicted

Phenotypic Suppression

FSW = 0.0950

Unknown

MTHSC70-2 (MITOCHONDRIAL HSP70 2) ATP BINDING
AT5G19550

Predicted

Gene fusion method

Phylogenetic profile method

Co-expression

FSW = 0.0754

Unknown

ASP2 (ASPARTATE AMINOTRANSFERASE 2) L-ASPARTATE2-OXOGLUTARATE AMINOTRANSFERASE
AT2G30970

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.0608

Unknown

ASP1 (ASPARTATE AMINOTRANSFERASE 1) L-ASPARTATE2-OXOGLUTARATE AMINOTRANSFERASE
AT3G26590

Predicted

Affinity Capture-MS

FSW = 0.0192

Unknown

MATE EFFLUX FAMILY PROTEIN
AT2G06530

Predicted

Synthetic Rescue

Synthetic Rescue

FSW = 0.0308

Unknown

VPS21
AT1G74560

Predicted

Synthetic Lethality

FSW = 0.1338

Unknown

NRP1 (NAP1-RELATED PROTEIN 1) DNA BINDING / CHROMATIN BINDING / HISTONE BINDING
AT3G22890

Predicted

Synthetic Lethality

FSW = 0.1772

Unknown

APS1 (ATP SULFURYLASE 1) SULFATE ADENYLYLTRANSFERASE (ATP)
AT1G20630

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.0396

Unknown

CAT1 (CATALASE 1) CATALASE
AT5G11520

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.0916

Unknown

ASP3 (ASPARTATE AMINOTRANSFERASE 3) L-ASPARTATE2-OXOGLUTARATE AMINOTRANSFERASE
AT5G09660

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.2323

Unknown

PMDH2 (PEROXISOMAL NAD-MALATE DEHYDROGENASE 2) MALATE DEHYDROGENASE
AT1G21640

Predicted

Phenotypic Enhancement

FSW = 0.0488

Unknown

NADK2 NAD+ KINASE/ CALMODULIN BINDING
AT1G48860

Predicted

Phenotypic Enhancement

FSW = 0.1319

Unknown

3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE PUTATIVE / 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE PUTATIVE / EPSP SYNTHASE PUTATIVE
AT4G31990

Predicted

Phylogenetic profile method

Co-expression

FSW = 0.1166

Unknown

ASP5 (ASPARTATE AMINOTRANSFERASE 5) L-ASPARTATE2-OXOGLUTARATE AMINOTRANSFERASE
AT3G54670

Predicted

Phenotypic Enhancement

FSW = 0.0708

Unknown

TTN8 (TITAN8) ATP BINDING / TRANSPORTER
AT1G02780

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0079

Unknown

EMB2386 (EMBRYO DEFECTIVE 2386) STRUCTURAL CONSTITUENT OF RIBOSOME
AT1G04750

Predicted

Synthetic Lethality

Synthetic Lethality

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.2146

Unknown

VAMP721 (VESICLE-ASSOCIATED MEMBRANE PROTEIN 721)
AT2G32670

Predicted

Phenotypic Enhancement

FSW = 0.1738

Unknown

ATVAMP725
AT1G50360

Predicted

interologs mapping

interologs mapping

FSW = 0.0338

Unknown

VIIIA MOTOR
AT4G33090

Predicted

Phenotypic Enhancement

FSW = 0.1390

Unknown

APM1 (AMINOPEPTIDASE M1) AMINOPEPTIDASE
AT4G21680

Predicted

Phenotypic Enhancement

FSW = 0.0866

Unknown

PROTON-DEPENDENT OLIGOPEPTIDE TRANSPORT (POT) FAMILY PROTEIN
AT3G46900

Predicted

Affinity Capture-MS

FSW = 0.0062

Unknown

COPT2 COPPER ION TRANSMEMBRANE TRANSPORTER/ HIGH AFFINITY COPPER ION TRANSMEMBRANE TRANSPORTER
AT2G37790

Predicted

Phenotypic Enhancement

FSW = 0.1106

Unknown

ALDO/KETO REDUCTASE FAMILY PROTEIN
AT3G13460

Predicted

Phenotypic Enhancement

FSW = 0.0793

Unknown

ECT2 PROTEIN BINDING
AT4G28860

Predicted

Phenotypic Enhancement

FSW = 0.0768

Unknown

CKL4 (CASEIN KINASE I-LIKE 4) ATP BINDING / KINASE/ PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT2G43810

Predicted

Affinity Capture-MS

FSW = 0.0089

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN F PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE / SM PROTEIN F PUTATIVE
AT5G27720

Predicted

Phenotypic Enhancement

FSW = 0.0100

Unknown

EMB1644 (EMBRYO DEFECTIVE 1644)
AT1G21700

Predicted

Synthetic Lethality

Synthetic Lethality

Synthetic Lethality

FSW = 0.1413

Unknown

ATSWI3C (SWITCH/SUCROSE NONFERMENTING 3C) DNA BINDING
AT1G56110

Predicted

Phenotypic Enhancement

FSW = 0.0355

Unknown

NOP56 (ARABIDOPSIS HOMOLOG OF NUCLEOLAR PROTEIN NOP56)
AT4G18880

Predicted

Affinity Capture-MS

FSW = 0.0285

Unknown

AT-HSFA4A DNA BINDING / TRANSCRIPTION FACTOR
AT4G25340

Predicted

Phenotypic Enhancement

FSW = 0.1091

Unknown

IMMUNOPHILIN-RELATED / FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED
AT3G54826

Predicted

Synthetic Rescue

Synthetic Rescue

FSW = 0.0476

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN CONTAINS INTERPRO DOMAIN/S ZINC FINGER ZIM17-TYPE (INTERPROIPR007853) HAS 284 BLAST HITS TO 284 PROTEINS IN 134 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 100 FUNGI - 79 PLANTS - 58 VIRUSES - 0 OTHER EUKARYOTES - 47 (SOURCE NCBI BLINK)
AT2G30160

Predicted

Phenotypic Enhancement

FSW = 0.1556

Unknown

MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN
AT3G18480

Predicted

Phenotypic Enhancement

FSW = 0.1013

Unknown

ATCASP (ARABIDOPSIS THALIANA CCAAT-DISPLACEMENT PROTEIN ALTERNATIVELY SPLICED PRODUCT)
AT5G24090

Predicted

Synthetic Lethality

FSW = 0.0983

Unknown

ACIDIC ENDOCHITINASE (CHIB1)
AT3G54300

Predicted

Affinity Capture-MS

FSW = 0.0132

Unknown

ATVAMP727 (VESICLE-ASSOCIATED MEMBRANE PROTEIN 727)
AT2G22540

Predicted

biochemical

FSW = 0.0067

Unknown

SVP (SHORT VEGETATIVE PHASE) TRANSCRIPTION FACTOR/ TRANSLATION REPRESSOR NUCLEIC ACID BINDING
AT3G19510

Predicted

Synthetic Rescue

Synthetic Rescue

FSW = 0.0489

Unknown

HAT31 DNA BINDING / SEQUENCE-SPECIFIC DNA BINDING / TRANSCRIPTION ACTIVATOR/ TRANSCRIPTION FACTOR
AT2G29540

Predicted

Phenotypic Enhancement

FSW = 0.0943

Unknown

ATRPC14 (RNA POLYMERASE 14 KDA SUBUNIT) DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION
AT1G20693

Predicted

Phenotypic Enhancement

Synthetic Lethality

FSW = 0.1979

Unknown

HMGB2 (HIGH MOBILITY GROUP B 2) DNA BINDING / CHROMATIN BINDING / STRUCTURAL CONSTITUENT OF CHROMATIN / TRANSCRIPTION FACTOR
AT1G25155Predicted

Phenotypic Enhancement

FSW = 0.1397

Unknown

ANTHRANILATE SYNTHASE BETA SUBUNIT PUTATIVE
AT1G44180

Predicted

Phenotypic Enhancement

synthetic growth defect

FSW = 0.1534

Unknown

AMINOACYLASE PUTATIVE / N-ACYL-L-AMINO-ACID AMIDOHYDROLASE PUTATIVE
AT1G47830

Predicted

Phenotypic Enhancement

Synthetic Lethality

FSW = 0.1835

Unknown

CLATHRIN COAT ASSEMBLY PROTEIN PUTATIVE
AT1G60680

Predicted

Phenotypic Enhancement

FSW = 0.1536

Unknown

ALDO/KETO REDUCTASE FAMILY PROTEIN
AT1G13950

Predicted

synthetic growth defect

FSW = 0.0082

Unknown

ELF5A-1 (EUKARYOTIC ELONGATION FACTOR 5A-1) TRANSLATION INITIATION FACTOR
AT1G33040

Predicted

Synthetic Lethality

FSW = 0.0438

Unknown

NACA5 (NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-LIKE PROTEIN 5)
AT1G35350

Predicted

synthetic growth defect

FSW = 0.2091

Unknown

LOCATED IN INTEGRAL TO MEMBRANE EXPRESSED IN 18 PLANT STRUCTURES EXPRESSED DURING 9 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S EXS C-TERMINAL (INTERPROIPR004342) SPX N-TERMINAL (INTERPROIPR004331) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS EXS FAMILY PROTEIN / ERD1/XPR1/SYG1 FAMILY PROTEIN (TAIRAT1G267301) HAS 734 BLAST HITS TO 697 PROTEINS IN 158 SPECIES ARCHAE - 0 BACTERIA - 21 METAZOA - 234 FUNGI - 245 PLANTS - 125 VIRUSES - 0 OTHER EUKARYOTES - 109 (SOURCE NCBI BLINK)
AT1G66590

Predicted

synthetic growth defect

FSW = 0.1645

Unknown

COX19 FAMILY PROTEIN
AT1G78770

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.1948

Unknown

CELL DIVISION CYCLE FAMILY PROTEIN
AT1G80510

Predicted

Phenotypic Enhancement

FSW = 0.0357

Unknown

AMINO ACID TRANSPORTER FAMILY PROTEIN
AT2G02000

Predicted

Phenotypic Suppression

FSW = 0.0137

Unknown

GAD3 (GLUTAMATE DECARBOXYLASE 3) CALMODULIN BINDING
AT2G31020

Predicted

Affinity Capture-MS

FSW = 0.0550

Unknown

ORP1A (OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1A) OXYSTEROL BINDING
AT3G11240

Predicted

Phenotypic Enhancement

FSW = 0.0886

Unknown

ATE2 (ARGININE-TRNA PROTEIN TRANSFERASE 2) ARGINYLTRANSFERASE
AT3G22290

Predicted

synthetic growth defect

FSW = 0.1845

Unknown

UNKNOWN PROTEIN
AT3G25900

Predicted

Affinity Capture-MS

two hybrid

Phenotypic Suppression

Reconstituted Complex

Co-crystal Structure

Affinity Capture-MS

FSW = 0.4039

Unknown

HMT-1 HOMOCYSTEINE S-METHYLTRANSFERASE
AT3G45240

Predicted

Phenotypic Enhancement

FSW = 0.2296

Unknown

GRIK1 (GEMINIVIRUS REP INTERACTING KINASE 1) KINASE
AT3G47610

Predicted

Synthetic Lethality

FSW = 0.1650

Unknown

TRANSCRIPTION REGULATOR/ ZINC ION BINDING
AT4G21490

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.2112

Unknown

NDB3 NADH DEHYDROGENASE
AT4G27130

Predicted

Synthetic Lethality

synthetic growth defect

FSW = 0.2619

Unknown

EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 PUTATIVE
AT4G29580

Predicted

Synthetic Lethality

FSW = 0.1987

Unknown

CYTIDINE DEAMINASE PUTATIVE / CYTIDINE AMINOHYDROLASE PUTATIVE
AT5G16980

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.2352

Unknown

NADP-DEPENDENT OXIDOREDUCTASE PUTATIVE
AT5G17860

Predicted

Synthetic Lethality

Synthetic Lethality

FSW = 0.1706

Unknown

CAX7 (CALCIUM EXCHANGER 7) CALCIUMSODIUM ANTIPORTER/ CATIONCATION ANTIPORTER
AT5G67540

Predicted

Phenotypic Enhancement

FSW = 0.1475

Unknown

GLYCOSYL HYDROLASE FAMILY PROTEIN 43
AT1G66740

Predicted

Phenotypic Enhancement

FSW = 0.0173

Unknown

SGA2
AT2G26000

Predicted

Synthetic Rescue

FSW = 0.0416

Unknown

ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN
AT3G06483

Predicted

Phenotypic Enhancement

FSW = 0.0790

Unknown

PDK (PYRUVATE DEHYDROGENASE KINASE) ATP BINDING / HISTIDINE PHOSPHOTRANSFER KINASE/ PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE
AT3G11230

Predicted

Phenotypic Enhancement

FSW = 0.1787

Unknown

YIPPEE FAMILY PROTEIN
AT3G50110

Predicted

interologs mapping

FSW = 0.0132

Unknown

ATPEN3 (ARABIDOPSIS THALIANA PTEN 3) PHOSPHATASE/ PROTEIN TYROSINE PHOSPHATASE/ PROTEIN TYROSINE/SERINE/THREONINE PHOSPHATASE
AT4G19645

Predicted

Phenotypic Enhancement

FSW = 0.0620

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN INTEGRAL TO MEMBRANE CONTAINS INTERPRO DOMAIN/S TRAM LAG1 AND CLN8 HOMOLOGY (INTERPROIPR006634) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT1G313002) HAS 401 BLAST HITS TO 401 PROTEINS IN 98 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 186 FUNGI - 102 PLANTS - 84 VIRUSES - 0 OTHER EUKARYOTES - 29 (SOURCE NCBI BLINK)
AT5G01770

Predicted

Phenotypic Enhancement

FSW = 0.2250

Unknown

RAPTOR2 (RAPTOR2) BINDING / NUCLEOTIDE BINDING
AT5G24840

Predicted

Phenotypic Suppression

FSW = 0.0386

Unknown

TRNA (GUANINE-N7-)-METHYLTRANSFERASE
AT5G61010

Predicted

Phenotypic Enhancement

FSW = 0.1168

Unknown

ATEXO70E2 (EXOCYST SUBUNIT EXO70 FAMILY PROTEIN E2) PROTEIN BINDING

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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454