Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G15090 - ( VDAC3 (VOLTAGE DEPENDENT ANION CHANNEL 3) voltage-gated anion channel )

71 Proteins interacs with AT5G15090
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G01280

Predicted

Synthetic Lethality

FSW = 0.0143

Class C:

vacuole

unclear

plastid

plasma membrane

mitochondrion

VDAC1 (VOLTAGE DEPENDENT ANION CHANNEL 1) VOLTAGE-GATED ANION CHANNEL
AT5G67500

Predicted

Phenotypic Enhancement

synthetic growth defect

FSW = 0.0236

Class C:

vacuole

unclear

plastid

mitochondrion

VDAC2 (VOLTAGE DEPENDENT ANION CHANNEL 2) VOLTAGE-GATED ANION CHANNEL
AT2G33120

Predicted

Affinity Capture-MS

FSW = 0.0108

Class C:

vacuole

unclear

plasma membrane

SAR1 (SYNAPTOBREVIN-RELATED PROTEIN 1)
AT3G20000

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Synthetic Lethality

FSW = 0.0827

Class C:

vacuole

unclear

mitochondrion

TOM40 P-P-BOND-HYDROLYSIS-DRIVEN PROTEIN TRANSMEMBRANE TRANSPORTER/ VOLTAGE-GATED ANION CHANNEL
AT4G17730

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0240

Class C:

vacuole

unclear

SYP23 (SYNTAXIN OF PLANTS 23) SNAP RECEPTOR
AT5G02500

Predicted

Affinity Capture-MS

FSW = 0.0100

Class C:

vacuole

plastid

plasma membrane

nucleus

HSC70-1 (HEAT SHOCK COGNATE PROTEIN 70-1) ATP BINDING
AT1G23190

Predicted

Affinity Capture-MS

FSW = 0.0201

Class C:

vacuole

plastid

plasma membrane

PHOSPHOGLUCOMUTASE CYTOPLASMIC PUTATIVE / GLUCOSE PHOSPHOMUTASE PUTATIVE
AT3G08710

Predicted

Synthetic Lethality

FSW = 0.0432

Class C:

vacuole

plasma membrane

ATH9 (THIOREDOXIN H-TYPE 9)
AT1G31780

Predicted

Affinity Capture-MS

FSW = 0.0274

Class C:

vacuole

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 24 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S CONSERVED OLIGOMERIC COMPLEX COG6 (INTERPROIPR010490) HAS 281 BLAST HITS TO 279 PROTEINS IN 131 SPECIES ARCHAE - 0 BACTERIA - 2 METAZOA - 132 FUNGI - 106 PLANTS - 21 VIRUSES - 0 OTHER EUKARYOTES - 20 (SOURCE NCBI BLINK)
AT4G29260

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

FSW = 0.1772

Class C:

vacuole

ACID PHOSPHATASE CLASS B FAMILY PROTEIN
AT5G26030

Predicted

Synthetic Lethality

FSW = 0.0203

Class C:

unclear

plastid

mitochondrion

FC1 (FERROCHELATASE 1) FERROCHELATASE
AT5G57490

Predicted

Gene fusion method

Co-expression

FSW = 0.0764

Class C:

unclear

plasma membrane

mitochondrion

VDAC4 (VOLTAGE DEPENDENT ANION CHANNEL 4) VOLTAGE-GATED ANION CHANNEL
AT1G07790

Predicted

Synthetic Lethality

FSW = 0.0079

Class C:

plastid

nucleus

HTB1 DNA BINDING
AT1G55920

Predicted

Synthetic Lethality

FSW = 0.0377

Class C:

plastid

nucleus

ATSERAT21 (SERINE ACETYLTRANSFERASE 21) SERINE O-ACETYLTRANSFERASE
AT5G42130

Predicted

Synthetic Lethality

FSW = 0.0267

Class C:

plastid

mitochondrion

MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN
AT5G51820

Predicted

Synthetic Lethality

FSW = 0.0872

Class C:

plastid

PGM (PHOSPHOGLUCOMUTASE) PHOSPHOGLUCOMUTASE
AT5G62880

Predicted

Affinity Capture-MS

FSW = 0.0589

Class C:

plasma membrane

nucleus

ARAC10 GTP BINDING
AT3G45780

Predicted

two hybrid

FSW = 0.0324

Class C:

plasma membrane

PHOT1 (PHOTOTROPIN 1) FMN BINDING / BLUE LIGHT PHOTORECEPTOR/ KINASE/ PROTEIN BINDING / PROTEIN SERINE/THREONINE KINASE
AT1G20760

Predicted

Synthetic Lethality

FSW = 0.0030

Class C:

plasma membrane

CALCIUM-BINDING EF HAND FAMILY PROTEIN
AT5G25754Predicted

two hybrid

two hybrid

FSW = 0.0145

Class C:

plasma membrane

UNKNOWN PROTEIN
AT2G25070

Predicted

Affinity Capture-MS

FSW = 0.0160

Class C:

plasma membrane

PROTEIN PHOSPHATASE 2C PUTATIVE / PP2C PUTATIVE
AT5G45970

Predicted

Affinity Capture-Western

Affinity Capture-MS

FSW = 0.0070

Class C:

plasma membrane

ARAC2 (ARABIDOPSIS RAC-LIKE 2) GTP BINDING
AT5G02490

Predicted

Synthetic Lethality

FSW = 0.0185

Class C:

plasma membrane

HEAT SHOCK COGNATE 70 KDA PROTEIN 2 (HSC70-2) (HSP70-2)
AT4G21680

Predicted

Affinity Capture-MS

FSW = 0.0404

Class C:

plasma membrane

PROTON-DEPENDENT OLIGOPEPTIDE TRANSPORT (POT) FAMILY PROTEIN
AT5G43900

Predicted

Synthetic Lethality

FSW = 0.0330

Class C:

nucleus

MYA2 (ARABIDOPSIS MYOSIN 2) GTP-DEPENDENT PROTEIN BINDING / RAB GTPASE BINDING / MOTOR
AT2G44860

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Synthetic Lethality

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-Western

Synthetic Lethality

Co-purification

co-fractionation

Co-fractionation

FSW = 0.0617

Class C:

nucleus

60S RIBOSOMAL PROTEIN L24 PUTATIVE
AT2G44510

Predicted

Synthetic Lethality

FSW = 0.0406

Class C:

nucleus

P21CIP1-BINDING PROTEIN-RELATED
AT4G34430

Predicted

Synthetic Lethality

Affinity Capture-MS

FSW = 0.0369

Class C:

nucleus

CHB3 DNA BINDING / TRANSCRIPTION FACTOR/ ZINC ION BINDING
AT2G03870

Predicted

Affinity Capture-MS

FSW = 0.0112

Class C:

nucleus

SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE
AT2G41380

Predicted

Synthetic Lethality

Synthetic Lethality

FSW = 0.0563

Class C:

mitochondrion

EMBRYO-ABUNDANT PROTEIN-RELATED
AT2G20510

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

FSW = 0.2404

Class C:

mitochondrion

ATTIM44-1 PROTEIN-TRANSMEMBRANE TRANSPORTING ATPASE
AT1G13560

Predicted

two hybrid

interaction prediction

FSW = 0.0209

Class C:

mitochondrion

AAPT1 (AMINOALCOHOLPHOSPHOTRANSFERASE 1) PHOSPHATIDYLTRANSFERASE/ PHOSPHOTRANSFERASE FOR OTHER SUBSTITUTED PHOSPHATE GROUPS
AT5G66590

Predicted

Synthetic Lethality

FSW = 0.0833

Unknown

ALLERGEN V5/TPX-1-RELATED FAMILY PROTEIN
AT3G08730

Predicted

Synthetic Lethality

FSW = 0.0021

Unknown

PK1 (PROTEIN-SERINE KINASE 1) KINASE/ PROTEIN BINDING / PROTEIN KINASE/ PROTEIN SERINE/THREONINE KINASE
AT2G18230

Predicted

Synthetic Lethality

FSW = 0.0197

Unknown

ATPPA2 (ARABIDOPSIS THALIANA PYROPHOSPHORYLASE 2) INORGANIC DIPHOSPHATASE/ PYROPHOSPHATASE
AT5G10330Predicted

Affinity Capture-MS

FSW = 0.0394

Unknown

HPA1 (HISTIDINOL PHOSPHATE AMINOTRANSFERASE 1) HISTIDINOL-PHOSPHATE TRANSAMINASE
AT3G13900

Predicted

Affinity Capture-MS

FSW = 0.0122

Unknown

ATPASE COUPLED TO TRANSMEMBRANE MOVEMENT OF IONS PHOSPHORYLATIVE MECHANISM
AT1G71790

Predicted

two hybrid

two hybrid

FSW = 0.0074

Unknown

F-ACTIN CAPPING PROTEIN BETA SUBUNIT FAMILY PROTEIN
AT1G15440

Predicted

Synthetic Lethality

FSW = 0.0403

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT1G22550

Predicted

Affinity Capture-MS

Affinity Capture-MS

FSW = 0.0565

Unknown

PROTON-DEPENDENT OLIGOPEPTIDE TRANSPORT (POT) FAMILY PROTEIN
AT1G25500

Predicted

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-Western

Synthetic Lethality

Co-purification

FSW = 0.1379

Unknown

CHOLINE TRANSPORTER-RELATED
AT1G52500

Predicted

Synthetic Lethality

FSW = 0.0656

Unknown

ATMMH-1 (ARABIDOPSIS THALIANA MUTM HOMOLOG-1) DNA N-GLYCOSYLASE
AT1G60680

Predicted

Synthetic Lethality

FSW = 0.0251

Unknown

ALDO/KETO REDUCTASE FAMILY PROTEIN
AT1G66810

Predicted

Affinity Capture-MS

FSW = 0.0421

Unknown

ZINC FINGER (CCCH-TYPE) FAMILY PROTEIN
AT1G79820

Predicted

Affinity Capture-MS

FSW = 0.0117

Unknown

SGB1 (SUPPRESSOR OF G PROTEIN BETA1) CARBOHYDRATE TRANSMEMBRANE TRANSPORTER/ SUGARHYDROGEN SYMPORTER
AT2G31260

Predicted

Synthetic Lethality

FSW = 0.1249

Unknown

APG9 (AUTOPHAGY 9)
AT2G39590

Predicted

Synthetic Lethality

FSW = 0.0054

Unknown

40S RIBOSOMAL PROTEIN S15A (RPS15AC)
AT2G47090

Predicted

Synthetic Lethality

Affinity Capture-MS

FSW = 0.0679

Unknown

NUCLEIC ACID BINDING / PROTEIN BINDING / ZINC ION BINDING
AT2G48100

Predicted

Synthetic Lethality

FSW = 0.0523

Unknown

EXONUCLEASE FAMILY PROTEIN
AT3G02000

Predicted

Synthetic Lethality

FSW = 0.0258

Unknown

ROXY1 DISULFIDE OXIDOREDUCTASE
AT3G08700

Predicted

Synthetic Lethality

FSW = 0.0066

Unknown

UBC12 (UBIQUITIN-CONJUGATING ENZYME 12) SMALL CONJUGATING PROTEIN LIGASE/ UBIQUITIN-PROTEIN LIGASE
AT3G20650

Predicted

Synthetic Lethality

FSW = 0.0022

Unknown

MRNA CAPPING ENZYME FAMILY PROTEIN
AT3G47300

Predicted

Affinity Capture-MS

FSW = 0.0383

Unknown

SELT (SELT-LIKE PROTEIN PRECURSOR) SELENIUM BINDING
AT3G57140

Predicted

Synthetic Lethality

FSW = 0.0938

Unknown

PATATIN-RELATED
AT3G59540Predicted

Synthetic Lethality

FSW = 0.0736

Unknown

60S RIBOSOMAL PROTEIN L38 (RPL38B)
AT3G62760

Predicted

Synthetic Lethality

FSW = 0.0096

Unknown

ATGSTF13 GLUTATHIONE TRANSFERASE
AT4G18593

Predicted

Synthetic Lethality

FSW = 0.0401

Unknown

DUAL SPECIFICITY PROTEIN PHOSPHATASE-RELATED
AT5G01640

Predicted

Affinity Capture-MS

FSW = 0.0551

Unknown

PRA1B5 (PRENYLATED RAB ACCEPTOR 1B5)
AT5G01670

Predicted

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-Western

Synthetic Lethality

Co-purification

FSW = 0.0702

Unknown

ALDOSE REDUCTASE PUTATIVE
AT1G25510

Predicted

Affinity Capture-MS

FSW = 0.0401

Unknown

ASPARTYL PROTEASE FAMILY PROTEIN
AT4G16370

Predicted

Affinity Capture-MS

FSW = 0.0618

Unknown

ATOPT3 (OLIGOPEPTIDE TRANSPORTER) OLIGOPEPTIDE TRANSPORTER
AT4G19880

Predicted

Affinity Capture-MS

FSW = 0.0322

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN RESPONSE TO CADMIUM ION LOCATED IN CHLOROPLAST EXPRESSED IN 23 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S GLUTATHIONE S-TRANSFERASE PREDICTED (INTERPROIPR016639) GLUTATHIONE S-TRANSFERASE C-TERMINAL (INTERPROIPR004046) GLUTATHIONE S-TRANSFERASE C-TERMINAL-LIKE (INTERPROIPR010987) GLUTATHIONE S-TRANSFERASE/CHLORIDE CHANNEL C-TERMINAL (INTERPROIPR017933) THIOREDOXIN-LIKE FOLD (INTERPROIPR012336) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT5G450201) HAS 1635 BLAST HITS TO 1635 PROTEINS IN 489 SPECIES ARCHAE - 12 BACTERIA - 905 METAZOA - 23 FUNGI - 158 PLANTS - 57 VIRUSES - 0 OTHER EUKARYOTES - 480 (SOURCE NCBI BLINK)
AT4G29910

Predicted

Affinity Capture-MS

FSW = 0.0072

Unknown

ORC5 (ORIGIN RECOGNITION COMPLEX PROTEIN 5) PROTEIN BINDING
AT5G05070

Predicted

Synthetic Lethality

FSW = 0.0241

Unknown

ZINC ION BINDING
AT5G16040

Predicted

Affinity Capture-Western

Synthetic Lethality

FSW = 0.0115

Unknown

REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY PROTEIN
AT5G26250

Predicted

Affinity Capture-MS

FSW = 0.0686

Unknown

SUGAR TRANSPORTER PUTATIVE
AT5G57480

Predicted

synthetic growth defect

Synthetic Lethality

Reconstituted Complex

Synthetic Lethality

Affinity Capture-Western

Synthetic Rescue

synthetic growth defect

FSW = 0.0590

Unknown

AAA-TYPE ATPASE FAMILY PROTEIN
AT5G27970Predicted

Synthetic Lethality

FSW = 0.0042

Unknown

BINDING
AT5G55180

Predicted

Affinity Capture-MS

FSW = 0.0401

Unknown

GLYCOSYL HYDROLASE FAMILY 17 PROTEIN
AT5G59040

Predicted

Affinity Capture-MS

FSW = 0.0590

Unknown

COPT3 COPPER ION TRANSMEMBRANE TRANSPORTER/ HIGH AFFINITY COPPER ION TRANSMEMBRANE TRANSPORTER
AT5G61010

Predicted

Affinity Capture-MS

FSW = 0.0255

Unknown

ATEXO70E2 (EXOCYST SUBUNIT EXO70 FAMILY PROTEIN E2) PROTEIN BINDING

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454