Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G35910 - ( 3-5 exonuclease domain-containing protein / helicase and RNase D C-terminal domain-containing protein / HRDC domain-containing protein )
83 Proteins interacs with AT5G35910| Locus | Method | FSW  | Cellular Compartment Classification (C3) | Description |
|---|---|---|---|---|
AT1G79280
   | PredictedPhenotypic Enhancement | FSW = 0.0489
| Class C:nucleus | NUA (NUCLEAR PORE ANCHOR) |
| AT3G48750
| Predictedbiochemicalinteraction prediction | FSW = 0.0183
| Class C:nucleus | CDC2 (CELL DIVISION CONTROL 2) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING / PROTEIN KINASE |
| AT5G43900
| Predictedinteraction prediction | FSW = 0.0204
| Class C:nucleus | MYA2 (ARABIDOPSIS MYOSIN 2) GTP-DEPENDENT PROTEIN BINDING / RAB GTPASE BINDING / MOTOR |
| AT2G44680
| PredictedPhenotypic Enhancement | FSW = 0.1009
| Class C:nucleus | CKB4 (CASEIN KINASE II BETA SUBUNIT 4) PROTEIN SERINE/THREONINE KINASE |
| AT4G21010
| PredictedPhenotypic Enhancement | FSW = 0.0296
| Class C:nucleus | TRANSCRIPTION INITIATION FACTOR-RELATED |
| AT3G12810
| PredictedPhenotypic Enhancement | FSW = 0.2011
| Class C:nucleus | PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING |
| AT3G44530
| PredictedPhenotypic Enhancement | FSW = 0.1316
| Class C:nucleus | HIRA (ARABIDOPSIS HOMOLOG OF HISTONE CHAPERONE HIRA) NUCLEOTIDE BINDING / PROTEIN BINDING |
| AT5G37720
| PredictedSynthetic LethalityAffinity Capture-Western | FSW = 0.0674
| Class C:nucleus | RNA AND EXPORT FACTOR-BINDING PROTEIN PUTATIVE |
| AT1G02680
| PredictedPhenotypic Enhancement | FSW = 0.0448
| Class C:nucleus | TAF13 (TBP-ASSOCIATED FACTOR 13) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION FACTOR |
| AT2G43810
| PredictedPhenotypic Suppression | FSW = 0.1399
| Class C:nucleus | SMALL NUCLEAR RIBONUCLEOPROTEIN F PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE / SM PROTEIN F PUTATIVE |
| AT5G64630
| PredictedPhenotypic Enhancement | FSW = 0.0591
| Class C:nucleus | FAS2 (FASCIATA 2) NUCLEOTIDE BINDING / PROTEIN BINDING |
| AT1G19120
| PredictedPhenotypic Suppression | FSW = 0.1105
| Class C:nucleus | SMALL NUCLEAR RIBONUCLEOPROTEIN PUTATIVE / SNRNP PUTATIVE / SM PROTEIN PUTATIVE |
| AT4G17020
| PredictedPhenotypic Enhancement | FSW = 0.0457
| Class C:nucleus | TRANSCRIPTION FACTOR-RELATED |
| AT1G03190
| PredictedSynthetic Rescue | FSW = 0.1304
| Class C:nucleus | UVH6 (ULTRAVIOLET HYPERSENSITIVE 6) ATP BINDING / ATP-DEPENDENT DNA HELICASE/ ATP-DEPENDENT HELICASE/ DNA BINDING / HYDROLASE ACTING ON ACID ANHYDRIDES IN PHOSPHORUS-CONTAINING ANHYDRIDES / NUCLEIC ACID BINDING |
| AT1G17980
| PredictedSynthetic RescueAffinity Capture-WesternSynthetic Rescue | FSW = 0.0364
| Class C:nucleus | NUCLEOTIDYLTRANSFERASE FAMILY PROTEIN |
| AT2G47620
| PredictedPhenotypic Enhancement | FSW = 0.0472
| Class C:nucleus | ATSWI3A (SWITCH/SUCROSE NONFERMENTING 3A) DNA BINDING |
| AT3G06720
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinteraction prediction | FSW = 0.0795
| Class C:nucleus | IMPA-1 (IMPORTIN ALPHA ISOFORM 1) BINDING / PROTEIN TRANSPORTER |
| AT1G05055
| PredictedPhenotypic Enhancement | FSW = 0.1277
| Class C:nucleus | GTF2H2 (GENERAL TRANSCRIPTION FACTOR IIH 2) GENERAL RNA POLYMERASE II TRANSCRIPTION FACTOR |
| AT1G07370
| PredictedPhenotypic Enhancement | FSW = 0.0960
| Class C:nucleus | PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN) DNA BINDING / DNA POLYMERASE PROCESSIVITY FACTOR/ PROTEIN BINDING |
| AT1G72560
| Predictedinterologs mapping | FSW = 0.0057
| Class C:nucleus | PSD (PAUSED) NUCLEOBASE NUCLEOSIDE NUCLEOTIDE AND NUCLEIC ACID TRANSMEMBRANE TRANSPORTER/ TRNA BINDING |
| AT2G15430
| PredictedPhenotypic Suppression | FSW = 0.0797
| Class C:nucleus | NRPB3 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION |
| AT2G36740
| PredictedPhenotypic Enhancement | FSW = 0.2617
| Class C:nucleus | SWC2 DNA BINDING / TRANSCRIPTION FACTOR |
| AT2G38560
| PredictedSynthetic Rescue | FSW = 0.1323
| Class C:nucleus | TFIIS (TRANSCRIPT ELONGATION FACTOR IIS) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION ELONGATION FACTOR/ TRANSCRIPTION FACTOR |
| AT2G18760
| Predictedsynthetic growth defect | FSW = 0.0452
| Class C:nucleus | CHR8 (CHROMATIN REMODELING 8) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING |
| AT3G60500
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MS | FSW = 0.1818
| Class C:nucleus | CER7 (ECERIFERUM 7) 3-5-EXORIBONUCLEASE/ RNA BINDING |
| AT2G33210
| Predictedpull down | FSW = 0.0023
| Unknown | HSP60-2 (HEAT SHOCK PROTEIN 60-2) ATP BINDING |
| AT1G64790 | PredictedPhenotypic Enhancement | FSW = 0.0874
| Unknown | BINDING |
| AT4G01370
| PredictedPhenotypic Enhancement | FSW = 0.0151
| Unknown | ATMPK4 (ARABIDOPSIS THALIANA MAP KINASE 4) MAP KINASE/ KINASE |
| AT3G02520
| PredictedPhenotypic Enhancement | FSW = 0.0711
| Unknown | GRF7 (GENERAL REGULATORY FACTOR 7) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING |
| AT5G53480
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MS | FSW = 0.0288
| Unknown | IMPORTIN BETA-2 PUTATIVE |
| AT4G35800
| PredictedAffinity Capture-MS | FSW = 0.0707
| Unknown | NRPB1 (RNA POLYMERASE II LARGE SUBUNIT) DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
| AT4G38740
| PredictedPhenotypic Enhancement | FSW = 0.0130
| Unknown | ROC1 (ROTAMASE CYP 1) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE |
| AT5G26830
| PredictedAffinity Capture-MS | FSW = 0.0098
| Unknown | THREONYL-TRNA SYNTHETASE / THREONINE--TRNA LIGASE (THRRS) |
| AT1G29880
| PredictedAffinity Capture-MS | FSW = 0.0109
| Unknown | GLYCYL-TRNA SYNTHETASE / GLYCINE--TRNA LIGASE |
| AT1G75510
| PredictedPhenotypic Enhancement | FSW = 0.1654
| Unknown | TRANSCRIPTION INITIATION FACTOR IIF BETA SUBUNIT (TFIIF-BETA) FAMILY PROTEIN |
| AT1G03360
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-Westerntwo hybrid | FSW = 0.1182
| Unknown | ATRRP4 (ARABIDOPSIS THALIANA RIBOSOMAL RNA PROCESSING 4) RNA BINDING / EXONUCLEASE |
| AT1G06790
| PredictedPhenotypic Enhancement | FSW = 0.0287
| Unknown | RNA POLYMERASE RPB7 N-TERMINAL DOMAIN-CONTAINING PROTEIN |
| AT1G08780
| PredictedPhenotypic Suppression | FSW = 0.1268
| Unknown | AIP3 (ABI3-INTERACTING PROTEIN 3) UNFOLDED PROTEIN BINDING |
| AT1G49760
| PredictedSynthetic RescueSynthetic Rescue | FSW = 0.0355
| Unknown | PAB8 (POLY(A) BINDING PROTEIN 8) RNA BINDING / TRANSLATION INITIATION FACTOR |
| AT1G51710
| PredictedPhenotypic Enhancement | FSW = 0.1627
| Unknown | UBP6 (UBIQUITIN-SPECIFIC PROTEASE 6) CALMODULIN BINDING / UBIQUITIN-SPECIFIC PROTEASE |
| AT1G54140
| PredictedPhenotypic Suppression | FSW = 0.0684
| Unknown | TAFII21 (TATA BINDING PROTEIN ASSOCIATED FACTOR 21KDA SUBUNIT) DNA BINDING / TRANSCRIPTION INITIATION FACTOR |
| AT1G54390
| PredictedPhenotypic Enhancement | FSW = 0.1039
| Unknown | PHD FINGER PROTEIN-RELATED |
| AT1G59760
| PredictedAffinity Capture-MSAffinity Capture-MSinterologs mapping | FSW = 0.0697
| Unknown | ATP-DEPENDENT RNA HELICASE PUTATIVE |
| AT1G63160
| PredictedPhenotypic Enhancement | FSW = 0.0553
| Unknown | REPLICATION FACTOR C 40 KDA PUTATIVE |
| AT2G17510
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinterologs mappinginteraction prediction | FSW = 0.0728
| Unknown | EMB2763 (EMBRYO DEFECTIVE 2763) RNA BINDING / RIBONUCLEASE |
| AT2G19540
| PredictedAffinity Capture-MS | FSW = 0.0138
| Unknown | TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN |
| AT2G26970
| Predictedinterologs mapping | FSW = 0.0218
| Unknown | EXONUCLEASE FAMILY PROTEIN |
| AT3G10070
| PredictedPhenotypic Suppression | FSW = 0.0690
| Unknown | TAF12 (TBP-ASSOCIATED FACTOR 12) DNA BINDING / TRANSCRIPTION INITIATION FACTOR |
| AT3G13230
| PredictedAffinity Capture-MS | FSW = 0.0227
| Unknown | RNA BINDING |
| AT3G18860
| PredictedPhenotypic Enhancement | FSW = 0.1470
| Unknown | TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN |
| AT3G22480
| PredictedPhenotypic Suppression | FSW = 0.0850
| Unknown | PREFOLDIN-RELATED KE2 FAMILY PROTEIN |
| AT3G27730
| PredictedPhenotypic Suppression | FSW = 0.0460
| Unknown | RCK (ROCK-N-ROLLERS) ATP BINDING / ATP-DEPENDENT HELICASE/ DNA HELICASE |
| AT3G54380
| PredictedPhenotypic Enhancement | FSW = 0.2295
| Unknown | SAC3/GANP FAMILY PROTEIN |
| AT3G61620
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSPhenotypic Enhancementinteraction predictionCo-expression | FSW = 0.1333
| Unknown | RRP41 3-5-EXORIBONUCLEASE/ RNA BINDING |
| AT4G22140
| PredictedPhenotypic Enhancement | FSW = 0.1258
| Unknown | DNA BINDING / PROTEIN BINDING / ZINC ION BINDING |
| AT4G32175
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MS | FSW = 0.1325
| Unknown | RNA BINDING |
| AT5G10260
| PredictedPhenotypic Enhancement | FSW = 0.1338
| Unknown | ATRABH1E (ARABIDOPSIS RAB GTPASE HOMOLOG H1E) GTP BINDING |
| AT5G10390 | PredictedPhenotypic Enhancement | FSW = 0.0519
| Unknown | HISTONE H3 |
| AT5G11200
| Predictedsynthetic growth defectSynthetic LethalitySynthetic Rescuesynthetic growth defect | FSW = 0.0390
| Unknown | DEAD/DEAH BOX HELICASE PUTATIVE |
| AT5G13780
| PredictedPhenotypic Suppression | FSW = 0.0655
| Unknown | GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE |
| AT5G23290
| PredictedPhenotypic Suppression | FSW = 0.0610
| Unknown | PDF5 (PREFOLDIN 5) UNFOLDED PROTEIN BINDING |
| AT5G25800
| Predictedinterologs mapping | FSW = 0.0115
| Unknown | EXONUCLEASE FAMILY PROTEIN |
| AT5G27970 | PredictedPhenotypic Suppression | FSW = 0.0727
| Unknown | BINDING |
| AT1G04160
| PredictedAffinity Capture-MS | FSW = 0.0291
| Unknown | XIB (MYOSIN XI B) MOTOR |
| AT1G16800
| Predictedsynthetic growth defect | FSW = 0.0615
| Unknown | TRNA-SPLICING ENDONUCLEASE POSITIVE EFFECTOR-RELATED |
| AT1G17760
| PredictedSynthetic Rescue | FSW = 0.0385
| Unknown | CSTF77 PROTEIN BINDING |
| AT1G18090
| PredictedPhenotypic Enhancement | FSW = 0.0182
| Unknown | EXONUCLEASE PUTATIVE |
| AT1G60620
| PredictedAffinity Capture-MSPhenotypic Enhancement | FSW = 0.0345
| Unknown | ATRPAC43 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ PROTEIN DIMERIZATION |
| AT1G79730
| Predictedsynthetic growth defect | FSW = 0.1381
| Unknown | ELF7 (EARLY FLOWERING 7) |
| AT2G22400
| PredictedSynthetic Rescue | FSW = 0.0898
| Unknown | NOL1/NOP2/SUN FAMILY PROTEIN |
| AT3G22590
| PredictedSynthetic LethalitySynthetic Lethalityinteraction predictionCo-expression | FSW = 0.1397
| Unknown | RNA POL II ACCESSORY FACTOR CDC73 FAMILY PROTEIN |
| AT5G24840
| PredictedSynthetic Rescue | FSW = 0.0094
| Unknown | TRNA (GUANINE-N7-)-METHYLTRANSFERASE |
| AT5G35930
| PredictedSynthetic Rescue | FSW = 0.0262
| Unknown | AMP-DEPENDENT SYNTHETASE AND LIGASE FAMILY PROTEIN |
| AT5G38890
| PredictedAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSAffinity Capture-MSinteraction prediction | FSW = 0.0500
| Unknown | EXORIBONUCLEASE-RELATED |
| AT5G53770
| PredictedSynthetic LethalityPhenotypic Enhancement | FSW = 0.0874
| Unknown | NUCLEOTIDYLTRANSFERASE FAMILY PROTEIN |
| AT5G55310
| PredictedPhenotypic Suppression | FSW = 0.1630
| Unknown | TOP1BETA (DNA TOPOISOMERASE 1 BETA) DNA TOPOISOMERASE TYPE I |
| AT5G40530
| PredictedAffinity Capture-MS | FSW = 0.0500
| Unknown | EXPRESSED IN 22 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S METHYLTRANSFERASE-RELATED (INTERPROIPR007823) HAS 293 BLAST HITS TO 293 PROTEINS IN 141 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 93 FUNGI - 88 PLANTS - 22 VIRUSES - 0 OTHER EUKARYOTES - 90 (SOURCE NCBI BLINK) |
| AT5G41880
| PredictedPhenotypic Enhancement | FSW = 0.0586
| Unknown | POLA3 DNA PRIMASE |
| AT5G45600
| PredictedPhenotypic Enhancement | FSW = 0.1823
| Unknown | GAS41 PROTEIN BINDING |
| AT5G51940
| PredictedSynthetic Rescue | FSW = 0.0535
| Unknown | NRPB6A DNA BINDING / DNA-DIRECTED RNA POLYMERASE |
| AT5G65180
| PredictedPhenotypic Enhancement | FSW = 0.1490
| Unknown | FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN EXPRESSED IN 18 PLANT STRUCTURES EXPRESSED DURING 9 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S PROTEIN OF UNKNOWN FUNCTION DUF618 (INTERPROIPR006903) REGULATION OF NUCLEAR PRE-MRNA PROTEIN (INTERPROIPR006569) ENTH/VHS (INTERPROIPR008942) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS UNKNOWN PROTEIN (TAIRAT5G100601) HAS 3523 BLAST HITS TO 3241 PROTEINS IN 333 SPECIES ARCHAE - 25 BACTERIA - 251 METAZOA - 1575 FUNGI - 421 PLANTS - 142 VIRUSES - 17 OTHER EUKARYOTES - 1092 (SOURCE NCBI BLINK) |
| AT5G66100
| PredictedPhenotypic Suppression | FSW = 0.1729
| Unknown | LA DOMAIN-CONTAINING PROTEIN |
| AT3G12990
| Predictedinteraction prediction | FSW = 0.1182
| Unknown | RRP45A (RIBONUCLEASE PH45A) 3-5-EXORIBONUCLEASE/ RNA BINDING |
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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from
FSW
FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in commonLearn more - FSWeight top ranked cut offs
C3
Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described
PEP
PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029Learn more
How to cite
If you find AtPIN interesting and want to use it in your work please cite usAtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454DOI:1471-2105/10/454
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