Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G19310 - ( homeotic gene regulator putative )

92 Proteins interacs with AT5G19310
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G49910

Predicted

Affinity Capture-MS

FSW = 0.0103

Class C:

nucleus

60S RIBOSOMAL PROTEIN L26 (RPL26A)
AT2G42740

Predicted

Affinity Capture-MS

FSW = 0.0228

Class C:

nucleus

RPL16A STRUCTURAL CONSTITUENT OF RIBOSOME
AT3G63130

Predicted

interologs mapping

synthetic growth defect

FSW = 0.0157

Class C:

nucleus

RANGAP1 (RAN GTPASE ACTIVATING PROTEIN 1) RAN GTPASE ACTIVATOR/ PROTEIN BINDING
AT5G59690Predicted

Synthetic Rescue

Synthetic Rescue

Affinity Capture-Western

FSW = 0.1153

Class C:

nucleus

HISTONE H4
AT1G26880

Predicted

Affinity Capture-MS

FSW = 0.0168

Class C:

nucleus

60S RIBOSOMAL PROTEIN L34 (RPL34A)
AT1G21700

Predicted

Affinity Capture-MS

Affinity Capture-MS

Co-purification

Co-purification

Co-purification

Co-purification

two hybrid

Co-purification

Affinity Capture-Western

Affinity Capture-MS

FSW = 0.0701

Class C:

nucleus

ATSWI3C (SWITCH/SUCROSE NONFERMENTING 3C) DNA BINDING
AT4G34430

Predicted

Co-purification

far western blotting

Reconstituted Complex

FSW = 0.0345

Class C:

nucleus

CHB3 DNA BINDING / TRANSCRIPTION FACTOR/ ZINC ION BINDING
AT1G75340

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

FSW = 0.0421

Class C:

nucleus

ZINC FINGER (CCCH-TYPE) FAMILY PROTEIN
AT5G14170

Predicted

Co-purification

FSW = 0.0284

Class C:

nucleus

CHC1
AT3G01890

Predicted

Affinity Capture-MS

Affinity Capture-MS

Co-purification

FSW = 0.1225

Class C:

nucleus

SWIB COMPLEX BAF60B DOMAIN-CONTAINING PROTEIN
AT3G54610

Predicted

Phenotypic Enhancement

synthetic growth defect

Synthetic Lethality

Phenotypic Enhancement

Synthetic Lethality

synthetic growth defect

interaction prediction

FSW = 0.1538

Class C:

nucleus

GCN5 DNA BINDING / H3 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE
AT3G12810

Predicted

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.0934

Class C:

nucleus

PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT5G03415

Predicted

Phenotypic Enhancement

Phenotypic Enhancement

Co-expression

FSW = 0.0309

Class C:

nucleus

DPB PROTEIN BINDING / PROTEIN HETERODIMERIZATION
AT3G13445

Predicted

Affinity Capture-Western

Synthetic Lethality

interologs mapping

FSW = 0.0610

Class C:

nucleus

TBP1 (TATA BINDING PROTEIN 1) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION FACTOR/ BINDING
AT3G44530

Predicted

Affinity Capture-Western

interaction prediction

FSW = 0.0575

Class C:

nucleus

HIRA (ARABIDOPSIS HOMOLOG OF HISTONE CHAPERONE HIRA) NUCLEOTIDE BINDING / PROTEIN BINDING
AT2G33610

Predicted

interaction prediction

interologs mapping

FSW = 0.2335

Class C:

nucleus

ATSWI3B (SWITCH SUBUNIT 3) DNA BINDING
AT4G24440

Predicted

interologs mapping

Synthetic Lethality

FSW = 0.0469

Class C:

nucleus

TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN / TFIIA-GAMMA (TFIIA-S)
AT1G18450

Predicted

Co-purification

FSW = 0.0428

Class C:

nucleus

ATARP4 STRUCTURAL CONSTITUENT OF CYTOSKELETON
AT2G47620

Predicted

two hybrid

interologs mapping

interaction prediction

FSW = 0.1015

Class C:

nucleus

ATSWI3A (SWITCH/SUCROSE NONFERMENTING 3A) DNA BINDING
AT3G57300

Predicted

Phenotypic Enhancement

FSW = 0.0529

Class C:

nucleus

INO80 (INO80 ORTHOLOG) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT3G62310

Predicted

Affinity Capture-MS

FSW = 0.0178

Class C:

nucleus

RNA HELICASE PUTATIVE
AT2G27470

Predicted

Affinity Capture-Western

Co-purification

FSW = 0.0831

Class C:

nucleus

NF-YB11 (NUCLEAR FACTOR Y SUBUNIT B11) TRANSCRIPTION FACTOR
AT1G07470

Predicted

interologs mapping

FSW = 0.0262

Class C:

nucleus

TRANSCRIPTION FACTOR IIA LARGE SUBUNIT PUTATIVE / TFIIA LARGE SUBUNIT PUTATIVE
AT1G65440

Predicted

Synthetic Rescue

Synthetic Rescue

FSW = 0.0377

Class C:

nucleus

GTB1 RNA BINDING / HYDROLASE ACTING ON ESTER BONDS / TRANSCRIPTION ELONGATION REGULATOR
AT2G13370

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.0623

Class C:

nucleus

CHR5 (CHROMATIN REMODELING 5) ATP BINDING / DNA BINDING / CHROMATIN BINDING / HELICASE/ NUCLEIC ACID BINDING
AT2G38560

Predicted

Synthetic Lethality

FSW = 0.0689

Class C:

nucleus

TFIIS (TRANSCRIPT ELONGATION FACTOR IIS) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION ELONGATION FACTOR/ TRANSCRIPTION FACTOR
AT3G17590

Predicted

Phenotypic Enhancement

Affinity Capture-MS

Affinity Capture-MS

Affinity Capture-MS

Co-purification

Co-purification

Co-purification

Phenotypic Enhancement

Phenotypic Enhancement

Affinity Capture-Western

Co-purification

Affinity Capture-MS

interaction prediction

FSW = 0.1823

Class C:

nucleus

BSH (BUSHY GROWTH) CHROMATIN BINDING / PROTEIN BINDING
AT2G41840

Predicted

Affinity Capture-MS

FSW = 0.0114

Class C:

nucleus

40S RIBOSOMAL PROTEIN S2 (RPS2C)
AT4G16660

Predicted

Phenotypic Suppression

FSW = 0.0198

Unknown

HEAT SHOCK PROTEIN 70 PUTATIVE / HSP70 PUTATIVE
AT3G15710

Predicted

Phenotypic Enhancement

FSW = 0.0393

Unknown

SIGNAL PEPTIDASE PUTATIVE
AT1G69620

Predicted

Affinity Capture-MS

FSW = 0.0375

Unknown

RPL34 (RIBOSOMAL PROTEIN L34) STRUCTURAL CONSTITUENT OF RIBOSOME
AT5G10350

Predicted

biochemical

Affinity Capture-Western

FSW = 0.0209

Unknown

POLYADENYLATE-BINDING PROTEIN FAMILY PROTEIN / PABP FAMILY PROTEIN
AT4G18730Predicted

Affinity Capture-MS

FSW = 0.0264

Unknown

RPL16B STRUCTURAL CONSTITUENT OF RIBOSOME
AT5G09650

Predicted

Affinity Capture-Western

FSW = 0.0456

Unknown

ATPPA6 (ARABIDOPSIS THALIANA PYROPHOSPHORYLASE 6) INORGANIC DIPHOSPHATASE/ PYROPHOSPHATASE
AT5G58230

Predicted

Affinity Capture-Western

Co-purification

FSW = 0.1096

Unknown

MSI1 (MULTICOPY SUPRESSOR OF IRA1) PROTEIN BINDING
AT2G01320

Predicted

Phenotypic Enhancement

FSW = 0.0383

Unknown

ABC TRANSPORTER FAMILY PROTEIN
ATCG00790Predicted

Affinity Capture-MS

FSW = 0.0099

Unknown

CHLOROPLAST GENE ENCODING A RIBOSOMAL PROTEIN L16 WHICH IS A CONSTITUENT OF 50S LARGE RIBOSOMAL SUBUNIT
AT4G38740

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0251

Unknown

ROC1 (ROTAMASE CYP 1) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
AT3G53890

Predicted

two hybrid

FSW = 0.0292

Unknown

40S RIBOSOMAL PROTEIN S21 (RPS21B)
AT1G75170

Predicted

Co-purification

FSW = 0.0083

Unknown

SEC14 CYTOSOLIC FACTOR FAMILY PROTEIN / PHOSPHOGLYCERIDE TRANSFER FAMILY PROTEIN
AT5G52640

Predicted

Synthetic Lethality

FSW = 0.0160

Unknown

ATHSP901 (HEAT SHOCK PROTEIN 901) ATP BINDING / UNFOLDED PROTEIN BINDING
AT5G08570

Predicted

Phenotypic Enhancement

FSW = 0.0044

Unknown

PYRUVATE KINASE PUTATIVE
AT1G54080

Predicted

interaction prediction

FSW = 0.0107

Unknown

OLIGOURIDYLATE-BINDING PROTEIN PUTATIVE
AT1G06390

Predicted

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.0338

Unknown

GSK1 (GSK3/SHAGGY-LIKE PROTEIN KINASE 1) GLYCOGEN SYNTHASE KINASE 3/ KINASE
AT2G37600

Predicted

Affinity Capture-MS

FSW = 0.0103

Unknown

60S RIBOSOMAL PROTEIN L36 (RPL36A)
AT1G15930

Predicted

Affinity Capture-MS

FSW = 0.0211

Unknown

40S RIBOSOMAL PROTEIN S12 (RPS12A)
AT5G13640

Predicted

Phenotypic Suppression

FSW = 0.0536

Unknown

ATPDAT PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE
AT2G23380

Predicted

Phenotypic Enhancement

FSW = 0.0559

Unknown

CLF (CURLY LEAF) TRANSCRIPTION FACTOR
AT4G16420

Predicted

Colocalization

synthetic growth defect

FSW = 0.0786

Unknown

ADA2B (HOMOLOG OF YEAST ADA2 2B) DNA BINDING / TRANSCRIPTION COACTIVATOR/ TRANSCRIPTION FACTOR
AT4G26840

Predicted

Affinity Capture-MS

FSW = 0.0178

Unknown

SUMO1 (SMALL UBIQUITIN-LIKE MODIFIER 1) PROTEIN BINDING / PROTEIN TAG
AT4G02020

Predicted

Phenotypic Enhancement

FSW = 0.0560

Unknown

SWN (SWINGER) TRANSCRIPTION FACTOR
AT3G14290

Predicted

two hybrid

FSW = 0.0309

Unknown

PAE2 ENDOPEPTIDASE/ PEPTIDASE/ THREONINE-TYPE ENDOPEPTIDASE
AT3G12280

Predicted

Phenotypic Enhancement

FSW = 0.0131

Unknown

RBR1 (RETINOBLASTOMA-RELATED 1) TRANSCRIPTION FACTOR BINDING
AT1G66740

Predicted

Phenotypic Enhancement

Phenotypic Suppression

Phenotypic Enhancement

FSW = 0.0547

Unknown

SGA2
AT3G61740

Predicted

Phenotypic Suppression

Phenotypic Enhancement

Phenotypic Suppression

Phenotypic Suppression

Phenotypic Suppression

Phenotypic Suppression

Phenotypic Suppression

Phenotypic Suppression

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Suppression

FSW = 0.0297

Unknown

SDG14 (SET DOMAIN PROTEIN 14) DNA BINDING / PROTEIN BINDING / ZINC ION BINDING
AT5G16680

Predicted

Reconstituted Complex

co-fractionation

Co-fractionation

Co-purification

Reconstituted Complex

Affinity Capture-Western

Co-purification

Affinity Capture-Western

Co-purification

Co-purification

Reconstituted Complex

Reconstituted Complex

Affinity Capture-Western

co-fractionation

Co-fractionation

FSW = 0.0536

Unknown

PHD FINGER FAMILY PROTEIN
AT1G44120

Predicted

Phenotypic Suppression

FSW = 0.0537

Unknown

C2 DOMAIN-CONTAINING PROTEIN / ARMADILLO/BETA-CATENIN REPEAT FAMILY PROTEIN
AT5G46250

Predicted

Phenotypic Suppression

Phenotypic Suppression

FSW = 0.0767

Unknown

RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN
AT5G07950

Predicted

Co-purification

FSW = 0.0179

Unknown

UNKNOWN PROTEIN
AT5G16270

Predicted

Co-purification

FSW = 0.0054

Unknown

SYN4 (SISTER CHROMATID COHESION 1 PROTEIN 4)
AT1G13950

Predicted

two hybrid

FSW = 0.0402

Unknown

ELF5A-1 (EUKARYOTIC ELONGATION FACTOR 5A-1) TRANSLATION INITIATION FACTOR
AT1G32130

Predicted

Synthetic Rescue

Phenotypic Suppression

FSW = 0.1592

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 25 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S TFIIS N-TERMINAL (INTERPROIPR017923) IWS1 C-TERMINAL (INTERPROIPR008654) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS IWS1 C-TERMINUS FAMILY PROTEIN (TAIRAT4G190001) HAS 907 BLAST HITS TO 871 PROTEINS IN 182 SPECIES ARCHAE - 4 BACTERIA - 14 METAZOA - 417 FUNGI - 195 PLANTS - 42 VIRUSES - 8 OTHER EUKARYOTES - 227 (SOURCE NCBI BLINK)
AT1G49760

Predicted

Affinity Capture-MS

FSW = 0.0109

Unknown

PAB8 (POLY(A) BINDING PROTEIN 8) RNA BINDING / TRANSLATION INITIATION FACTOR
AT1G52740

Predicted

Synthetic Lethality

FSW = 0.1086

Unknown

HTA9 (HISTONE H2A PROTEIN 9) DNA BINDING
AT2G33240Predicted

Colocalization

FSW = 0.0275

Unknown

XID MOTOR/ PROTEIN BINDING
AT3G24830

Predicted

Affinity Capture-MS

FSW = 0.0284

Unknown

60S RIBOSOMAL PROTEIN L13A (RPL13AB)
AT3G46320Predicted

Affinity Capture-Western

FSW = 0.1264

Unknown

HISTONE H4
AT3G49660

Predicted

Phenotypic Suppression

FSW = 0.0575

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G51520

Predicted

Phenotypic Enhancement

FSW = 0.0550

Unknown

DIACYLGLYCEROL ACYLTRANSFERASE FAMILY
AT3G55170

Predicted

Affinity Capture-MS

FSW = 0.0179

Unknown

60S RIBOSOMAL PROTEIN L35 (RPL35C)
AT4G36050

Predicted

Phenotypic Enhancement

synthetic growth defect

synthetic growth defect

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

Phenotypic Enhancement

synthetic growth defect

Affinity Capture-MS

Synthetic Lethality

FSW = 0.0441

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT4G36080Predicted

synthetic growth defect

FSW = 0.1219

Unknown

FAT DOMAIN-CONTAINING PROTEIN / PHOSPHATIDYLINOSITOL 3- AND 4-KINASE FAMILY PROTEIN
AT5G10390Predicted

Affinity Capture-Western

FSW = 0.1068

Unknown

HISTONE H3
AT5G10400Predicted

Affinity Capture-Western

FSW = 0.1388

Unknown

HISTONE H3
AT1G08880

Predicted

Affinity Capture-MS

FSW = 0.0725

Unknown

H2AXA DNA BINDING
AT1G15780

Predicted

Synthetic Lethality

two hybrid

FSW = 0.0604

Unknown

UNKNOWN PROTEIN
AT1G31660

Predicted

Affinity Capture-MS

FSW = 0.0107

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN BIOLOGICAL_PROCESS UNKNOWN LOCATED IN CELLULAR_COMPONENT UNKNOWN EXPRESSED IN 21 PLANT STRUCTURES EXPRESSED DURING 13 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S BYSTIN (INTERPROIPR007955) HAS 370 BLAST HITS TO 362 PROTEINS IN 156 SPECIES ARCHAE - 0 BACTERIA - 7 METAZOA - 139 FUNGI - 93 PLANTS - 32 VIRUSES - 0 OTHER EUKARYOTES - 99 (SOURCE NCBI BLINK)
AT1G54140

Predicted

Synthetic Lethality

FSW = 0.0859

Unknown

TAFII21 (TATA BINDING PROTEIN ASSOCIATED FACTOR 21KDA SUBUNIT) DNA BINDING / TRANSCRIPTION INITIATION FACTOR
AT1G80410

Predicted

synthetic growth defect

FSW = 0.0187

Unknown

EMB2753 (EMBRYO DEFECTIVE 2753) BINDING
AT3G14100

Predicted

Affinity Capture-MS

FSW = 0.0249

Unknown

OLIGOURIDYLATE-BINDING PROTEIN PUTATIVE
AT3G45630

Predicted

Synthetic Lethality

FSW = 0.0429

Unknown

RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN
AT3G51270

Predicted

Affinity Capture-MS

Affinity Capture-MS

interaction prediction

FSW = 0.0445

Unknown

ATP BINDING / CATALYTIC/ PROTEIN SERINE/THREONINE KINASE
AT4G22140

Predicted

synthetic growth defect

FSW = 0.1155

Unknown

DNA BINDING / PROTEIN BINDING / ZINC ION BINDING
AT4G38250

Predicted

Phenotypic Enhancement

FSW = 0.0367

Unknown

AMINO ACID TRANSPORTER FAMILY PROTEIN
AT5G04800

Predicted

Phenotypic Enhancement

FSW = 0.0167

Unknown

40S RIBOSOMAL PROTEIN S17 (RPS17D)
AT5G13780

Predicted

synthetic growth defect

FSW = 0.0292

Unknown

GCN5-RELATED N-ACETYLTRANSFERASE PUTATIVE
AT5G26250

Predicted

Phenotypic Suppression

FSW = 0.0182

Unknown

SUGAR TRANSPORTER PUTATIVE
AT5G44740

Predicted

biochemical

FSW = 0.0030

Unknown

POLH (Y-FAMILT DNA POLYMERASE H) DNA-DIRECTED DNA POLYMERASE
AT5G38110

Predicted

Phenotypic Suppression

Phenotypic Enhancement

FSW = 0.0122

Unknown

ASF1B (ANTI- SILENCING FUNCTION 1B)
AT5G50900

Predicted

Phenotypic Suppression

FSW = 0.0314

Unknown

ARMADILLO/BETA-CATENIN REPEAT FAMILY PROTEIN
AT2G28820Predicted

interaction prediction

FSW = 0.0139

Unknown

ARMADILLO/BETA-CATENIN REPEAT FAMILY PROTEIN
AT4G13650

Predicted

Gene fusion method

FSW = 0.0108

Unknown

PENTATRICOPEPTIDE (PPR) REPEAT-CONTAINING PROTEIN

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Fasta sequences:

Proteins

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Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454