Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT5G63610 - ( CDKE1 (CYCLIN-DEPENDENT KINASE E1) ATP binding / kinase/ protein kinase/ protein serine/threonine kinase )

83 Proteins interacs with AT5G63610
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT3G48750

Experimental

Affinity Capture-MS

protein complementation assay

affinity technology

FSW = 0.0804

Unknown

CDC2 (CELL DIVISION CONTROL 2) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT1G66750

Experimental

protein complementation assay

FSW = 0.1569

Unknown

CAK4 (CDK-ACTIVATING KINASE 4) KINASE/ PROTEIN BINDING / PROTEIN SERINE/THREONINE KINASE
AT5G48820

Experimental

protein complementation assay

FSW = 0.2331

Unknown

ICK6 (INHIBITOR/INTERACTOR WITH CYCLIN-DEPENDENT KINASE) CYCLIN BINDING / CYCLIN-DEPENDENT PROTEIN KINASE INHIBITOR
AT3G19150

Experimental

protein complementation assay

FSW = 0.1991

Unknown

KRP6 (KIP-RELATED PROTEIN 6) CYCLIN BINDING / CYCLIN-DEPENDENT PROTEIN KINASE INHIBITOR
AT3G50630

Experimental

protein complementation assay

FSW = 0.1935

Unknown

KRP2 (KIP-RELATED PROTEIN 2) CYCLIN-DEPENDENT PROTEIN KINASE INHIBITOR/ KINASE INHIBITOR/ PROTEIN BINDING
AT4G34160

Experimental

protein complementation assay

FSW = 0.1077

Unknown

CYCD31 (CYCLIN D31) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR/ PROTEIN BINDING
AT3G54180

Experimental

protein complementation assay

FSW = 0.1366

Unknown

CDKB11 (CYCLIN-DEPENDENT KINASE B11) CYCLIN-DEPENDENT PROTEIN KINASE/ KINASE/ PROTEIN BINDING
AT2G38620

Experimental

protein complementation assay

FSW = 0.1896

Unknown

CDKB12 (CYCLIN-DEPENDENT KINASE B12) CYCLIN BINDING / KINASE/ PROTEIN SERINE/THREONINE KINASE
AT5G25380

Experimental

protein complementation assay

FSW = 0.1520

Unknown

CYCA21 (CYCLIN A21) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT5G11300

Experimental

protein complementation assay

FSW = 0.0449

Unknown

CYC3B (MITOTIC-LIKE CYCLIN 3B FROM ARABIDOPSIS) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT1G15570

Experimental

protein complementation assay

FSW = 0.1134

Unknown

CYCA23 (CYCLIN A23) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT1G47230

Experimental

protein complementation assay

FSW = 0.0696

Unknown

CYCLIN PUTATIVE
AT1G70210

Experimental

protein complementation assay

FSW = 0.0762

Unknown

CYCD11 (CYCLIN D11) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT3G50070

Experimental

protein complementation assay

FSW = 0.1197

Unknown

CYCD33 (CYCLIN D33) CYCLIN-DEPENDENT PROTEIN KINASE
AT5G65420

Experimental

protein complementation assay

two hybrid

FSW = 0.1216

Unknown

CYCD41 (CYCLIN D41) CYCLIN-DEPENDENT PROTEIN KINASE REGULATOR
AT5G10440

Experimental

protein complementation assay

FSW = 0.1201

Unknown

CYCD42 (CYCLIN D42) CYCLIN-DEPENDENT PROTEIN KINASE
AT4G37630

Experimental

protein complementation assay

two hybrid

FSW = 0.1306

Unknown

CYCD51 (CYCLIN D51) CYCLIN-DEPENDENT PROTEIN KINASE
AT5G27620

Experimental

protein complementation assay

FSW = 0.0779

Unknown

CYCH1 (CYCLIN H1) CYCLIN-DEPENDENT PROTEIN KINASE/ PROTEIN BINDING / PROTEIN KINASE
AT3G02520

Predicted

Phenotypic Enhancement

FSW = 0.0531

Unknown

GRF7 (GENERAL REGULATORY FACTOR 7) PROTEIN BINDING / PROTEIN PHOSPHORYLATED AMINO ACID BINDING
AT1G16030

Predicted

Affinity Capture-Western

FSW = 0.0189

Unknown

HSP70B (HEAT SHOCK PROTEIN 70B) ATP BINDING
AT5G43530

Predicted

Phenotypic Suppression

FSW = 0.0371

Unknown

SNF2 DOMAIN-CONTAINING PROTEIN / HELICASE DOMAIN-CONTAINING PROTEIN / RING FINGER DOMAIN-CONTAINING PROTEIN
AT1G12520

Predicted

Phenotypic Suppression

FSW = 0.0405

Unknown

ATCCS (COPPER CHAPERONE FOR SOD1) SUPEROXIDE DISMUTASE/ SUPEROXIDE DISMUTASE COPPER CHAPERONE
AT4G35800

Predicted

Synthetic Rescue

Synthetic Rescue

in vivo

in vivo

in vitro

biochemical

biochemical

biochemical

co-fractionation

Co-fractionation

in vivo

Affinity Capture-Western

co-fractionation

Co-fractionation

in vitro

biochemical

Synthetic Rescue

FSW = 0.1177

Unknown

NRPB1 (RNA POLYMERASE II LARGE SUBUNIT) DNA BINDING / DNA-DIRECTED RNA POLYMERASE
AT5G23630

Predicted

Phenotypic Enhancement

FSW = 0.0323

Unknown

ATPASE E1-E2 TYPE FAMILY PROTEIN / HALOACID DEHALOGENASE-LIKE HYDROLASE FAMILIY PROTEIN
AT1G11890

Predicted

Phenotypic Suppression

FSW = 0.0687

Unknown

SEC22 TRANSPORTER
AT4G26110

Predicted

Phenotypic Suppression

FSW = 0.0100

Unknown

NAP11 (NUCLEOSOME ASSEMBLY PROTEIN11) DNA BINDING
AT2G18040

Predicted

Synthetic Rescue

FSW = 0.0772

Unknown

PIN1AT (PEPTIDYLPROLYL CIS/TRANS ISOMERASE NIMA-INTERACTING 1) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
AT1G21700

Predicted

Phenotypic Suppression

FSW = 0.0197

Unknown

ATSWI3C (SWITCH/SUCROSE NONFERMENTING 3C) DNA BINDING
AT4G34430

Predicted

co-fractionation

Co-fractionation

FSW = 0.0028

Unknown

CHB3 DNA BINDING / TRANSCRIPTION FACTOR/ ZINC ION BINDING
AT3G54610

Predicted

Affinity Capture-Western

FSW = 0.0946

Unknown

GCN5 DNA BINDING / H3 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE
AT1G17790

Predicted

biochemical

FSW = 0.0250

Unknown

DNA-BINDING BROMODOMAIN-CONTAINING PROTEIN
AT3G12480

Predicted

Synthetic Rescue

FSW = 0.0618

Unknown

NF-YC11 (NUCLEAR FACTOR Y SUBUNIT C11) DNA BINDING / TRANSCRIPTION FACTOR
AT5G59710

Predicted

interaction prediction

FSW = 0.0696

Unknown

VIP2 (VIRE2 INTERACTING PROTEIN2) PROTEIN BINDING / TRANSCRIPTION REGULATOR
AT3G44530

Predicted

synthetic growth defect

Phenotypic Enhancement

FSW = 0.1070

Unknown

HIRA (ARABIDOPSIS HOMOLOG OF HISTONE CHAPERONE HIRA) NUCLEOTIDE BINDING / PROTEIN BINDING
AT2G43810

Predicted

Phenotypic Enhancement

FSW = 0.0887

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN F PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE / SM PROTEIN F PUTATIVE
AT3G17590

Predicted

Affinity Capture-Western

co-fractionation

Co-fractionation

Phenotypic Suppression

FSW = 0.0918

Unknown

BSH (BUSHY GROWTH) CHROMATIN BINDING / PROTEIN BINDING
AT3G57300

Predicted

Phenotypic Enhancement

FSW = 0.0132

Unknown

INO80 (INO80 ORTHOLOG) ATP BINDING / DNA BINDING / HELICASE/ NUCLEIC ACID BINDING
AT1G02740

Predicted

Phenotypic Enhancement

FSW = 0.0822

Unknown

CHROMATIN BINDING
AT2G13370

Predicted

Phenotypic Enhancement

FSW = 0.0889

Unknown

CHR5 (CHROMATIN REMODELING 5) ATP BINDING / DNA BINDING / CHROMATIN BINDING / HELICASE/ NUCLEIC ACID BINDING
AT2G27470

Predicted

Phenotypic Suppression

FSW = 0.0414

Unknown

NF-YB11 (NUCLEAR FACTOR Y SUBUNIT B11) TRANSCRIPTION FACTOR
AT2G36740

Predicted

Phenotypic Enhancement

FSW = 0.1310

Unknown

SWC2 DNA BINDING / TRANSCRIPTION FACTOR
AT2G38560

Predicted

Affinity Capture-Western

Phenotypic Suppression

FSW = 0.1862

Unknown

TFIIS (TRANSCRIPT ELONGATION FACTOR IIS) DNA BINDING / RNA POLYMERASE II TRANSCRIPTION ELONGATION FACTOR/ TRANSCRIPTION FACTOR
AT4G08350

Predicted

synthetic growth defect

FSW = 0.0495

Unknown

GTA2 (GLOBAL TRANSCRIPTION FACTOR GROUP A2) STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION FACTOR
AT1G06230

Predicted

biochemical

FSW = 0.0351

Unknown

GTE4 (GLOBAL TRANSCRIPTION FACTOR GROUP E 4) DNA BINDING
AT2G34210

Predicted

synthetic growth defect

FSW = 0.0485

Unknown

STRUCTURAL CONSTITUENT OF RIBOSOME / TRANSCRIPTION ELONGATION REGULATOR/ TRANSCRIPTION INITIATION FACTOR
AT1G03330

Predicted

two hybrid

interaction prediction

FSW = 0.0069

Unknown

SMALL NUCLEAR RIBONUCLEOPROTEIN D PUTATIVE / SNRNP CORE SM-LIKE PROTEIN PUTATIVE / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN PUTATIVE
AT2G29900

Predicted

Phenotypic Enhancement

FSW = 0.0101

Unknown

PRESENILIN FAMILY PROTEIN
AT5G19910

Predicted

Phenotypic Suppression

Affinity Capture-MS

FSW = 0.2255

Unknown

SOH1 FAMILY PROTEIN
AT5G48630

Predicted

interaction prediction

two hybrid

two hybrid

two hybrid

Reconstituted Complex

Reconstituted Complex

in vivo

in vivo

in vitro

in vitro

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

co-fractionation

Co-fractionation

Affinity Capture-Western

co-fractionation

Co-fractionation

Affinity Capture-Western

Reconstituted Complex

in vivo

in vitro

two hybrid

interaction prediction

Enriched domain pair

Co-expression

FSW = 0.2367

Unknown

CYCLIN FAMILY PROTEIN
AT3G12980

Predicted

Affinity Capture-Western

co-fractionation

Co-fractionation

FSW = 0.0372

Unknown

HAC5 H3/H4 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE
AT3G21350

Predicted

in vitro

Affinity Capture-MS

FSW = 0.0378

Unknown

RNA POLYMERASE TRANSCRIPTIONAL REGULATION MEDIATOR-RELATED
AT5G41910

Predicted

Affinity Capture-MS

Affinity Capture-Western

FSW = 0.0525

Unknown

RNA POLYMERASE II MEDIATOR COMPLEX PROTEIN-RELATED
AT1G02080Predicted

two hybrid

interaction prediction

FSW = 0.0721

Unknown

TRANSCRIPTIONAL REGULATOR-RELATED
AT1G05910

Predicted

Phenotypic Enhancement

FSW = 0.1234

Unknown

CELL DIVISION CYCLE PROTEIN 48-RELATED / CDC48-RELATED
AT1G07705

Predicted

two hybrid

FSW = 0.0713

Unknown

TRANSCRIPTION REGULATOR
AT1G15780

Predicted

interologs mapping

Phenotypic Suppression

Affinity Capture-Western

Affinity Capture-MS

FSW = 0.1379

Unknown

UNKNOWN PROTEIN
AT1G29990

Predicted

Phenotypic Enhancement

FSW = 0.0662

Unknown

PDF6 (PREFOLDIN 6) UNFOLDED PROTEIN BINDING
AT1G51710

Predicted

Phenotypic Enhancement

FSW = 0.0694

Unknown

UBP6 (UBIQUITIN-SPECIFIC PROTEASE 6) CALMODULIN BINDING / UBIQUITIN-SPECIFIC PROTEASE
AT1G52740

Predicted

Phenotypic Enhancement

FSW = 0.1438

Unknown

HTA9 (HISTONE H2A PROTEIN 9) DNA BINDING
AT1G54320

Predicted

Phenotypic Enhancement

FSW = 0.0124

Unknown

LEM3 (LIGAND-EFFECT MODULATOR 3) FAMILY PROTEIN / CDC50 FAMILY PROTEIN
AT1G73960

Predicted

biochemical

FSW = 0.0280

Unknown

TAF2 (TBP-ASSOCIATED FACTOR 2) METALLOPEPTIDASE/ ZINC ION BINDING
AT2G41050

Predicted

biochemical

FSW = 0.0372

Unknown

PQ-LOOP REPEAT FAMILY PROTEIN / TRANSMEMBRANE FAMILY PROTEIN
AT3G01090

Predicted

two hybrid

Synthetic Rescue

Affinity Capture-Western

interaction prediction

FSW = 0.0699

Unknown

AKIN10 (ARABIDOPSIS SNF1 KINASE HOMOLOG 10) PROTEIN BINDING / PROTEIN KINASE
AT3G22480

Predicted

Phenotypic Suppression

FSW = 0.0927

Unknown

PREFOLDIN-RELATED KE2 FAMILY PROTEIN
AT3G22590

Predicted

two hybrid

Synthetic Lethality

Synthetic Lethality

interaction prediction

FSW = 0.1754

Unknown

RNA POL II ACCESSORY FACTOR CDC73 FAMILY PROTEIN
AT3G45630

Predicted

synthetic growth defect

FSW = 0.0779

Unknown

RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN
AT3G49660

Predicted

Affinity Capture-Western

two hybrid

FSW = 0.0732

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G58460

Predicted

biochemical

FSW = 0.0186

Unknown

ATRBL15 (ARABIDOPSIS RHOMBOID-LIKE PROTEIN 15)
AT3G58560

Predicted

Affinity Capture-Western

interaction prediction

FSW = 0.0980

Unknown

ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN
AT4G38630

Predicted

Phenotypic Suppression

FSW = 0.0238

Unknown

RPN10 (REGULATORY PARTICLE NON-ATPASE 10) PEPTIDE RECEPTOR
AT5G10270

Predicted

synthetic growth defect

FSW = 0.1231

Unknown

CDKC1 (CYCLIN-DEPENDENT KINASE C1) KINASE
AT5G10790

Predicted

Phenotypic Enhancement

FSW = 0.1072

Unknown

UBP22 (UBIQUITIN-SPECIFIC PROTEASE 22) UBIQUITIN THIOLESTERASE/ UBIQUITIN-SPECIFIC PROTEASE/ ZINC ION BINDING
AT5G48640

Predicted

two hybrid

Reconstituted Complex

two hybrid

two hybrid

Affinity Capture-Western

Affinity Capture-Western

Affinity Capture-Western

Reconstituted Complex

two hybrid

FSW = 0.3756

Unknown

CYCLIN FAMILY PROTEIN
AT5G61770

Predicted

Phenotypic Suppression

FSW = 0.0134

Unknown

PPAN (PETER PAN-LIKE PROTEIN)
AT1G54140

Predicted

Synthetic Lethality

FSW = 0.1604

Unknown

TAFII21 (TATA BINDING PROTEIN ASSOCIATED FACTOR 21KDA SUBUNIT) DNA BINDING / TRANSCRIPTION INITIATION FACTOR
AT2G44150

Predicted

Synthetic Lethality

FSW = 0.0887

Unknown

ASHH3 (HISTONE-LYSINE N-METHYLTRANSFERASE ASHH3) HISTONE-LYSINE N-METHYLTRANSFERASE
AT2G45000

Predicted

Phenotypic Suppression

FSW = 0.0191

Unknown

EMB2766 (EMBRYO DEFECTIVE 2766) STRUCTURAL CONSTITUENT OF NUCLEAR PORE
AT3G42660

Predicted

Phenotypic Suppression

FSW = 0.0887

Unknown

NUCLEOTIDE BINDING
AT5G03220

Predicted

Affinity Capture-MS

FSW = 0.0713

Unknown

TRANSCRIPTIONAL CO-ACTIVATOR-RELATED
AT5G58690

Predicted

Phenotypic Suppression

FSW = 0.0220

Unknown

PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN
AT5G63670

Predicted

synthetic growth defect

FSW = 0.1109

Unknown

SPT42 (SPT4 HOMOLOG 2) POSITIVE TRANSCRIPTION ELONGATION FACTOR/ ZINC ION BINDING
AT5G08565

Predicted

synthetic growth defect

FSW = 0.0670

Unknown

POSITIVE TRANSCRIPTION ELONGATION FACTOR/ ZINC ION BINDING
AT3G22800

Predicted

Gene fusion method

FSW = 0.0103

Unknown

LEUCINE-RICH REPEAT FAMILY PROTEIN / EXTENSIN FAMILY PROTEIN

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Fasta sequences:

Proteins

DNA

Quick help

Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

Learn more

How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454