Arabidopsis thaliana protein interaction network
Laboratório de Biologia Integrativa e Sistêmica (LaBIS)
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AT2G17520 - ( IRE1A endoribonuclease/ kinase )

88 Proteins interacs with AT2G17520
LocusMethodFSW Cellular Compartment Classification (C3)Description
AT5G66680

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.2624

Class C:

nucleus

endoplasmic reticulum

DGL1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE-PROTEIN GLYCOTRANSFERASE
AT3G11964Predicted

biochemical

FSW = 0.0016

Class C:

nucleus

RNA BINDING
AT1G48130

Predicted

biochemical

FSW = 0.0245

Class C:

nucleus

ATPER1 ANTIOXIDANT/ THIOREDOXIN PEROXIDASE
AT3G50670

Predicted

two hybrid

FSW = 0.0013

Class C:

nucleus

U1-70K (U1 SMALL NUCLEAR RIBONUCLEOPROTEIN-70K) RNA BINDING / NUCLEIC ACID BINDING / NUCLEOTIDE BINDING
AT3G54610

Predicted

two hybrid

Reconstituted Complex

Affinity Capture-Western

FSW = 0.0098

Class C:

nucleus

GCN5 DNA BINDING / H3 HISTONE ACETYLTRANSFERASE/ HISTONE ACETYLTRANSFERASE
AT2G30050

Predicted

interologs mapping

synthetic growth defect

FSW = 0.0677

Class C:

nucleus

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT2G01720

Predicted

Phenotypic Enhancement

FSW = 0.1657

Class C:

endoplasmic reticulum

RIBOPHORIN I FAMILY PROTEIN
AT1G77510

Predicted

Phenotypic Enhancement

FSW = 0.0776

Class C:

endoplasmic reticulum

ATPDIL1-2 (PDI-LIKE 1-2) PROTEIN DISULFIDE ISOMERASE
AT5G60640

Predicted

interologs mapping

FSW = 0.0475

Class C:

endoplasmic reticulum

ATPDIL1-4 (PDI-LIKE 1-4) PROTEIN DISULFIDE ISOMERASE
AT2G01470

Predicted

interologs mapping

interologs mapping

synthetic growth defect

FSW = 0.0842

Class C:

endoplasmic reticulum

STL2P (SEC12P-LIKE 2 PROTEIN) NUCLEOTIDE BINDING
AT1G14010

Predicted

interologs mapping

FSW = 0.0172

Class C:

endoplasmic reticulum

EMP24/GP25L/P24 FAMILY PROTEIN
AT3G07180

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.0299

Class C:

endoplasmic reticulum

GPI TRANSAMIDASE COMPONENT PIG-S-RELATED
AT4G01320

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1006

Class C:

endoplasmic reticulum

ATSTE24 ENDOPEPTIDASE/ METALLOENDOPEPTIDASE
AT3G07100

Predicted

interologs mapping

FSW = 0.0376

Class C:

endoplasmic reticulum

PROTEIN TRANSPORT PROTEIN SEC24 PUTATIVE
AT1G76490

Predicted

two hybrid

FSW = 0.0704

Class C:

endoplasmic reticulum

HMG1 (HYDROXY METHYLGLUTARYL COA REDUCTASE 1) HYDROXYMETHYLGLUTARYL-COA REDUCTASE
AT5G63840

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1681

Class C:

endoplasmic reticulum

RSW3 (RADIAL SWELLING 3) GLUCOSIDASE/ HYDROLASE HYDROLYZING O-GLYCOSYL COMPOUNDS
AT1G79940

Predicted

interologs mapping

FSW = 0.1224

Class C:

endoplasmic reticulum

ATERDJ2A HEAT SHOCK PROTEIN BINDING / UNFOLDED PROTEIN BINDING
AT5G23630

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.2111

Class C:

endoplasmic reticulum

ATPASE E1-E2 TYPE FAMILY PROTEIN / HALOACID DEHALOGENASE-LIKE HYDROLASE FAMILIY PROTEIN
AT1G11890

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1299

Class C:

endoplasmic reticulum

SEC22 TRANSPORTER
AT4G21180

Predicted

Phenotypic Enhancement

FSW = 0.1010

Class C:

endoplasmic reticulum

ATERDJ2B HEAT SHOCK PROTEIN BINDING / UNFOLDED PROTEIN BINDING
AT1G52600

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.0299

Class C:

endoplasmic reticulum

SIGNAL PEPTIDASE PUTATIVE
AT1G29330

Predicted

Synthetic Lethality

FSW = 0.0252

Class C:

endoplasmic reticulum

ERD2 (ENDOPLASMIC RETICULUM RETENTION DEFECTIVE 2) KDEL SEQUENCE BINDING / RECEPTOR
AT1G67490

Predicted

synthetic growth defect

FSW = 0.1691

Class C:

endoplasmic reticulum

GCS1 (GLUCOSIDASE 1) ALPHA-GLUCOSIDASE
AT2G39630

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1633

Class C:

endoplasmic reticulum

GLYCOSYL TRANSFERASE FAMILY 2 PROTEIN
AT1G18260

Predicted

interologs mapping

FSW = 0.1263

Class C:

endoplasmic reticulum

SUPPRESSOR OF LIN-12-LIKE PROTEIN-RELATED / SEL-1 PROTEIN-RELATED
AT1G76400

Predicted

interologs mapping

FSW = 0.1020

Class C:

endoplasmic reticulum

RIBOPHORIN I FAMILY PROTEIN
AT1G51740

Predicted

Phenotypic Enhancement

FSW = 0.0362

Class C:

endoplasmic reticulum

SYP81 (SYNTAXIN OF PLANTS 81) SNAP RECEPTOR/ PROTEIN BINDING
AT1G01020

Predicted

Phenotypic Enhancement

FSW = 0.0569

Class C:

endoplasmic reticulum

ARV1
AT3G56190

Predicted

synthetic growth defect

FSW = 0.0060

Unknown

ALPHA-SNAP2 (ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN 2) BINDING / SOLUBLE NSF ATTACHMENT PROTEIN
AT5G13710

Predicted

synthetic growth defect

FSW = 0.0656

Unknown

SMT1 (STEROL METHYLTRANSFERASE 1) STEROL 24-C-METHYLTRANSFERASE
AT4G34580

Predicted

synthetic growth defect

FSW = 0.0098

Unknown

COW1 (CAN OF WORMS1) PHOSPHATIDYLINOSITOL TRANSPORTER/ TRANSPORTER
AT5G52640

Predicted

synthetic growth defect

FSW = 0.0384

Unknown

ATHSP901 (HEAT SHOCK PROTEIN 901) ATP BINDING / UNFOLDED PROTEIN BINDING
AT1G19650

Predicted

synthetic growth defect

FSW = 0.0110

Unknown

SEC14 CYTOSOLIC FACTOR PUTATIVE / PHOSPHOGLYCERIDE TRANSFER PROTEIN PUTATIVE
AT1G65040

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.0891

Unknown

PROTEIN BINDING / ZINC ION BINDING
AT1G56330

Predicted

interologs mapping

FSW = 0.0880

Unknown

ATSAR1B (SECRETION-ASSOCIATED RAS 1 B) GTP BINDING
AT5G60790

Predicted

biochemical

FSW = 0.0024

Unknown

ATGCN1 TRANSPORTER
AT1G71820

Predicted

synthetic growth defect

FSW = 0.0044

Unknown

SEC6
AT5G26710

Predicted

biochemical

FSW = 0.0080

Unknown

GLUTAMATE-TRNA LIGASE PUTATIVE / GLUTAMYL-TRNA SYNTHETASE PUTATUVE / GLURS PUTATIVE
AT5G38460

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1857

Unknown

ALG6 ALG8 GLYCOSYLTRANSFERASE FAMILY PROTEIN
AT2G44660

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1326

Unknown

TRANSFERASE TRANSFERRING GLYCOSYL GROUPS / TRANSFERASE TRANSFERRING HEXOSYL GROUPS
AT4G39220

Predicted

Phenotypic Enhancement

FSW = 0.1092

Unknown

ATRER1A
AT4G16420

Predicted

Reconstituted Complex

FSW = 0.0046

Unknown

ADA2B (HOMOLOG OF YEAST ADA2 2B) DNA BINDING / TRANSCRIPTION COACTIVATOR/ TRANSCRIPTION FACTOR
AT1G02145

Predicted

Phenotypic Enhancement

FSW = 0.1503

Unknown

TRANSFERASE TRANSFERRING GLYCOSYL GROUPS
AT1G07430

Predicted

biochemical

FSW = 0.0202

Unknown

PROTEIN PHOSPHATASE 2C PUTATIVE / PP2C PUTATIVE
AT1G08750

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1318

Unknown

GPI-ANCHOR TRANSAMIDASE PUTATIVE
AT1G16560

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1625

Unknown

PER1-LIKE FAMILY PROTEIN
AT1G16900

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.0972

Unknown

SUGAR BINDING / TRANSFERASE TRANSFERRING GLYCOSYL GROUPS
AT1G17145

Predicted

biochemical

FSW = 0.0135

Unknown

PROTEIN BINDING / ZINC ION BINDING
AT1G20575

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.0787

Unknown

DOLICHYL-PHOSPHATE BETA-D-MANNOSYLTRANSFERASE PUTATIVE / DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE PUTATIVE / MANNOSE-P-DOLICHOL SYNTHASE PUTATIVE
AT1G49490

Predicted

biochemical

FSW = 0.0070

Unknown

LEUCINE-RICH REPEAT FAMILY PROTEIN / EXTENSIN FAMILY PROTEIN
AT1G57600

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1514

Unknown

MEMBRANE BOUND O-ACYL TRANSFERASE (MBOAT) FAMILY PROTEIN
AT1G57620

Predicted

Phenotypic Enhancement

FSW = 0.1434

Unknown

EMP24/GP25L/P24 FAMILY PROTEIN
AT1G69640

Predicted

Phenotypic Suppression

FSW = 0.0827

Unknown

SBH1 (SPHINGOID BASE HYDROXYLASE 1) CATALYTIC/ SPHINGOSINE HYDROXYLASE
AT1G18830Predicted

interologs mapping

FSW = 0.0827

Unknown

TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT1G26690

Predicted

Phenotypic Enhancement

FSW = 0.0224

Unknown

EMP24/GP25L/P24 FAMILY PROTEIN
AT1G60970

Predicted

interologs mapping

FSW = 0.0380

Unknown

CLATHRIN ADAPTOR COMPLEX SMALL CHAIN FAMILY PROTEIN
AT1G79990

Predicted

interologs mapping

FSW = 0.0975

Unknown

LOCATED IN ENDOMEMBRANE SYSTEM COPI VESICLE COAT GOLGI MEMBRANE EXPRESSED IN 25 PLANT STRUCTURES EXPRESSED DURING 15 GROWTH STAGES CONTAINS INTERPRO DOMAIN/S SYS1 HOMOLOGUE (INTERPROIPR016973) HAS 55556 BLAST HITS TO 24059 PROTEINS IN 620 SPECIES ARCHAE - 38 BACTERIA - 5697 METAZOA - 25539 FUNGI - 10898 PLANTS - 5309 VIRUSES - 0 OTHER EUKARYOTES - 8075 (SOURCE NCBI BLINK)
AT3G01340

Predicted

interologs mapping

interologs mapping

synthetic growth defect

FSW = 0.0695

Unknown

PROTEIN TRANSPORT PROTEIN SEC13 FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN
AT3G12180

Predicted

Phenotypic Enhancement

FSW = 0.1410

Unknown

CORNICHON FAMILY PROTEIN
AT3G55380

Predicted

Synthetic Lethality

Phenotypic Enhancement

FSW = 0.0768

Unknown

UBC14 (UBIQUITIN-CONJUGATING ENZYME 14) UBIQUITIN-PROTEIN LIGASE
AT4G14160

Predicted

interologs mapping

interologs mapping

Phenotypic Enhancement

FSW = 0.1300

Unknown

TRANSPORT PROTEIN PUTATIVE
AT4G37760

Predicted

Phenotypic Suppression

FSW = 0.0217

Unknown

SQE3 (SQUALENE EPOXIDASE 3) SQUALENE MONOOXYGENASE
AT5G50550

Predicted

interologs mapping

interologs mapping

synthetic growth defect

FSW = 0.1021

Unknown

WD-40 REPEAT FAMILY PROTEIN / ST12P PROTEIN PUTATIVE
AT5G52210

Predicted

interologs mapping

Phenotypic Suppression

FSW = 0.0780

Unknown

ATGB1 (ARABIDOPSIS THALIANA GTP-BINDING PROTEIN 1) GTP BINDING
AT5G63140

Predicted

Synthetic Lethality

Affinity Capture-Western

biochemical

FSW = 0.0398

Unknown

ATPAP29 (ARABIDOPSIS THALIANA PURPLE ACID PHOSPHATASE 29) ACID PHOSPHATASE/ PROTEIN SERINE/THREONINE PHOSPHATASE
AT2G22530

Predicted

Phenotypic Enhancement

FSW = 0.2127

Unknown

CATALYTIC/ TRANSFERASE
AT2G29210

Predicted

biochemical

FSW = 0.0186

Unknown

SPLICING FACTOR PWI DOMAIN-CONTAINING PROTEIN
AT2G43650

Predicted

biochemical

FSW = 0.0057

Unknown

EMB2777 (EMBRYO DEFECTIVE 2777)
AT2G47760

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.0357

Unknown

ALG3 ALPHA-13-MANNOSYLTRANSFERASE/ CATALYTIC
AT3G02320

Predicted

biochemical

FSW = 0.0109

Unknown

RNA BINDING / TRNA (GUANINE-N2-)-METHYLTRANSFERASE
AT3G09560

Predicted

biochemical

FSW = 0.0070

Unknown

LIPIN FAMILY PROTEIN
AT3G23270

Predicted

biochemical

FSW = 0.0170

Unknown

REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY PROTEIN
AT3G62240

Predicted

biochemical

FSW = 0.0114

Unknown

ZINC FINGER (C2H2 TYPE) FAMILY PROTEIN
AT4G17890

Predicted

biochemical

FSW = 0.0628

Unknown

AGD8 (ARF-GAP DOMAIN 8) ARF GTPASE ACTIVATOR/ DNA BINDING / ZINC ION BINDING
AT5G27470

Predicted

biochemical

FSW = 0.0119

Unknown

SERYL-TRNA SYNTHETASE / SERINE--TRNA LIGASE
AT5G42190

Predicted

biochemical

FSW = 0.0037

Unknown

ASK2 (ARABIDOPSIS SKP1-LIKE 2) PROTEIN BINDING / UBIQUITIN-PROTEIN LIGASE
AT5G45140

Predicted

biochemical

FSW = 0.0049

Unknown

NRPC2 DNA BINDING / DNA-DIRECTED RNA POLYMERASE/ RIBONUCLEOSIDE BINDING
AT1G09080

Predicted

interologs mapping

Affinity Capture-Western

interologs mapping

FSW = 0.0985

Unknown

BIP3 ATP BINDING
AT3G44340

Predicted

interologs mapping

FSW = 0.0972

Unknown

CEF (CLONE EIGHTY-FOUR) PROTEIN BINDING / TRANSPORTER/ ZINC ION BINDING
AT1G05520

Predicted

interologs mapping

Phenotypic Enhancement

FSW = 0.1210

Unknown

TRANSPORT PROTEIN PUTATIVE
AT5G02410

Predicted

interologs mapping

FSW = 0.0807

Unknown

DIE2/ALG10 FAMILY
AT3G46460

Predicted

interologs mapping

Synthetic Lethality

FSW = 0.0898

Unknown

UBC13 (UBIQUITIN-CONJUGATING ENZYME 13) UBIQUITIN-PROTEIN LIGASE
AT2G18240

Predicted

interologs mapping

FSW = 0.1154

Unknown

RER1 PROTEIN PUTATIVE
AT1G09580

Predicted

interologs mapping

FSW = 0.1464

Unknown

EMP24/GP25L/P24 FAMILY PROTEIN
AT1G12340

Predicted

interologs mapping

FSW = 0.0735

Unknown

FUNCTIONS IN MOLECULAR_FUNCTION UNKNOWN INVOLVED IN INTRACELLULAR SIGNALING CASCADE LOCATED IN MEMBRANE EXPRESSED IN MALE GAMETOPHYTE POLLEN TUBE EXPRESSED DURING L MATURE POLLEN STAGE M GERMINATED POLLEN STAGE CONTAINS INTERPRO DOMAIN/S CORNICHON (INTERPROIPR003377) BEST ARABIDOPSIS THALIANA PROTEIN MATCH IS CORNICHON FAMILY PROTEIN (TAIRAT1G123901) HAS 463 BLAST HITS TO 463 PROTEINS IN 125 SPECIES ARCHAE - 0 BACTERIA - 0 METAZOA - 278 FUNGI - 110 PLANTS - 41 VIRUSES - 0 OTHER EUKARYOTES - 34 (SOURCE NCBI BLINK)
AT1G14290

Predicted

interologs mapping

FSW = 0.0776

Unknown

SBH2 (SPHINGOID BASE HYDROXYLASE 2) CATALYTIC/ SPHINGOSINE HYDROXYLASE
AT1G58440

Predicted

interologs mapping

FSW = 0.0328

Unknown

XF1 SQUALENE MONOOXYGENASE
AT3G07740

Predicted

Reconstituted Complex

FSW = 0.0095

Unknown

ADA2A (HOMOLOG OF YEAST ADA2 2A) DNA BINDING / TRANSCRIPTION FACTOR

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Experimental: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from
Predicted: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from

FSW

FSW is the Functional Similarity Weight. It represents the proportion of interaction partners that two proteins have in common

Learn more - FSWeight top ranked cut offs

C3

Class A: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated and both, target and source, were indicated as expressed in same cellular compartment
Class B: The PPI is a direct evidence (experimental), the subcellular location was experimentally demonstrated but both, target and source, were indicated as expressed in different cellular compartment
Class C: Same as Class A but the PPI is predicted
Class D: Same as Class A but subcellular location was predicted. P(exp|pred) indicates the probability of this particular predicted location be experimentally demonstrated given all data available on AtPINDB
Unknown: There is no available data to calculate the C3 or the data does not fit onto any class previously described

PEP

PEP is the posterior probability of this particular PPI be experimentally demonstrated once it was predicted. For this release p = 0.0030. If they share same cell compartment p = 0.0029

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How to cite

If you find AtPIN interesting and want to use it in your work please cite us

AtPIN: Arabidopsis thaliana Protein Interaction Network
Marcelo M Brandao, Luiza L Dantas and Marcio C Silva-Filho
BMC Bioinformatics 2009, 10:454

DOI:1471-2105/10/454